東京大学 · 生化学・遺伝学・分子生物学
阿部川修一教授の研究室は、微生物の遺伝的・分子的特徴解明を柱とし、特に淡水魚に発生するアエロモナス属細菌の系統解析や、海洋無脊椎動物のミトコンドリアゲノムの構造・進化を対象としています。分子標識(rpoD、gyrB、16S rDNA)を用いた系統分類と、ERCC-PCRやRFLP解析による遺伝的多様性の評価が主な手法です。また、エヒノデルムのミトコンドリアゲノムの遺伝子配置の保存と変異の解明を通じて、進化的な関係を解明しています。
Figures are computed from collected data and may differ slightly.
A total of 74 phenotypically identified presumptive motile Aeromonas isolates recovered from septicaemic freshwater ornamental fish in Sri Lanka were genetically characterized by sequencing of rpoD and gyrB genes. rpoD/gyrB phylogeny confirmed only 53 isolates as Aeromonas, among which A. veronii was the predominant species (79.2%), followed by A. hydrophila (7.5%), A. caviae (5.7%), A. jandaei (1.9%), A. dhakensis (3.8%) and A. entero pelogenes (1.9%). The aeromonads confirmed by sequencing wer
The 16,260-bp mitochondrial DNA (mtDNA) from the starfish Asterina pectinifera has been sequenced. The genes for 13 proteins, two rRNAs and 22 tRNAs are organized in an extremely economical fashion, similar to those of other animal mtDNAs, with some of the genes overlapping each other. The gene organization is the same as that for another echinoderm, sea urchin, except for the inversion of a 4.6-kb segment that contains genes for two proteins, 13 tRNAs and the 16S rRNA. Judging from the organiza
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