Seoul National University · 工学
Professor Su A Park's research lab specializes in advanced biomaterials and 3D bioprinting for regenerative medicine, with a primary focus on developing functional bioinks and scaffolds for bone tissue engineering. The lab explores nanocomposite hydrogels, including alginate-based systems reinforced with graphene oxide or polydopamine-coated gold nanoparticles, to enhance printability, structural stability, and osteogenic differentiation. Key research directions include designing cell-laden 3D constructs with tunable mechanical and biological properties, as well as optimizing bioink formulations using natural polymers like hyaluronic acid and silk fibroin for improved biocompatibility and in vitro cell performance. The lab integrates materials science, bioengineering, and cell biology to advance personalized tissue regeneration strategies.
Figures are computed from collected data and may differ slightly.
Three-dimensional (3D) cell printing is a versatile technique enabling the creation of 3D constructs containing hydrogel and cells in the desired shape or pattern. Bioinks exhibiting appropriate mechanical properties and biological activities to support cell growth and/or differentiation toward a specific lineage play critical roles in 3D cell printing and tissue engineering applications. Herein, we explored alginate/graphene oxide (GO) composites as bioinks for their potential to improve printa
In this study, we designed scaffolds coated with gold nanoparticles (GNPs) grown on a polydopamine (PDA) coating of a three-dimensional (3D) printed polycaprolactone (PCL) scaffold. Our results demonstrated that the scaffolds developed here may represent an innovative paradigm in bone tissue engineering by inducing osteogenesis as a means of remodeling and healing bone defects.
Bioprinting is an emerging technology for manufacturing cell-laden three-dimensional (3D) scaffolds, which are used to fabricate complex 3D constructs and provide specific microenvironments for supporting cell growth and differentiation. The development of bioinks with appropriate printability and specific bioactivities is crucial for bioprinting and tissue engineering applications, including bone tissue regeneration. Therefore, to produce functional bioinks for osteoblast printing and bone tiss
Three-dimensional (3D) bioprinting is a technology under active study for use in tissue engineering and regenerative medicine. Bioink comprises cells and polymers and is the essential material for 3D bioprinting. The characteristics of the bioink affect its printability, gelation behavior, and cell compatibility. In this study, alginate derivatives were synthesized to induce rapid gelation, and a bioink was prepared by mixing these alginate derivatives with silk fibroin to enhance cell compatibi
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