Yonsei University · 医学
Professor Sung Soo Ahn's research lab specializes in diagnostic and prognostic radiology, with a focus on advanced medical imaging techniques for accurate tumor characterization and personalized treatment planning. The lab investigates the application of dynamic contrast-enhanced MRI, radiomics, and machine learning to improve the diagnosis and prognosis of glioblastoma and hepatocellular carcinoma. A key emphasis is placed on integrating molecular biomarkers—such as MGMT methylation status and genetic alterations in gliomas—into radiological interpretation to support precision oncology.
Figures are computed from collected data and may differ slightly.
Hepatobiliary phase images obtained after gadoxetic acid-enhanced dynamic MR imaging may improve diagnosis of HCC and assist in surgical planning.
The Kim and American Association of Clinical Endocrinologists criteria are more accurate than the Society of Radiologists in Ultrasound criteria. The American Association of Clinical Endocrinologists guidelines are recommended for achieving high specificity, and the Kim criteria may be chosen for higher sensitivity.
Primary angiographic shapes of symptomatic intracranial VBDs differed between ruptured and unruptured lesions. The stenosis-without-dilatation lesions most frequently exhibited radiologic improvement at follow-up imaging, followed by pearl-and-string and dilatation-without-stenosis lesions.
Ktrans may serve as a potential imaging biomarker to predict MGMT methylation status preoperatively in glioblastoma; however, further investigation with a larger cohort is necessary.
We evaluated the diagnostic performance and generalizability of traditional machine learning and deep learning models for distinguishing glioblastoma from single brain metastasis using radiomics. The training and external validation cohorts comprised 166 (109 glioblastomas and 57 metastases) and 82 (50 glioblastomas and 32 metastases) patients, respectively. Two-hundred-and-sixty-five radiomic features were extracted from semiautomatically segmented regions on contrast-enhancing and peritumoral
The fifth edition of the World Health Organization (WHO) classification of central nervous system tumors published in 2021 advances the role of molecular diagnostics in the classification of gliomas by emphasizing integrated diagnoses based on histopathology and molecular information and grouping tumors based on genetic alterations. Importantly, molecular biomarkers that provide important prognostic information are now a parameter for establishing tumor grades in gliomas. Understanding the 2021
This study aims to determine how randomly splitting a dataset into training and test sets affects the estimated performance of a machine learning model and its gap from the test performance under different conditions, using real-world brain tumor radiomics data. We conducted two classification tasks of different difficulty levels with magnetic resonance imaging (MRI) radiomics features: (1) "Simple" task, glioblastomas [n = 109] vs. brain metastasis [n = 58] and (2) "difficult" task, low- [n = 1
With the advances in diffusion magnetic resonance (MR) imaging techniques, diffusion tensor imaging (DTI) has been applied to a number of neurological conditions because DTI can demonstrate microstructures of the brain that are not assessable with conventional MR imaging. Tractography based on DTI offers gross visualization of the white matter fiber architecture in the human brain in vivo. Degradation of restrictive barriers and disruption of the cytoarchitecture result in changes in the diffusi
Myocardial fat was detected in 22.4% of MI patients and was more frequently associated with a longer postinfarct period, milder coronary artery stenosis, fewer number of diseased vessels, and more severe regional wall motion abnormalities.
Open papers in the app to read, cite, and organize with AI.