東京工業大学 · 工学
伊久保俊行教授の研究室では、生体適合性を有するハイドロキシアpatサイト（HAp）を基盤としたナノ構造材料の設計・開発を進めています。特に、3次元多孔質構造を有するHAp/コラーゲン複合材料の力学的特性と生体適合性を制御し、骨再生医療への応用を追求しています。また、HApナノ結晶を用いたタンパク質吸着・洗浄の再現性評価や、バイオセンシング技術の開発にも取り組んでいます。
Figures are computed from collected data and may differ slightly.
This study investigated the effects of the three-dimensional (3-D) pore structure of a porous hydroxyapatite/collagen (HAp/Col) composite on their mechanical properties and in vivo tissue ingrowth. The unique 3-D pore structure, comprising unidirectionally interconnected pores, was fabricated by the unidirectional growth of ice crystals by using a cooling stage and a subsequent freeze-drying process. The unidirectional pores had a spindle-shaped cross section, and their size gradually increased
The repeatability of the adsorption and removal of fibrinogen and fetal bovine serum on hydroxyapatite (HAp) nanocrystal sensors was investigated by Fourier transform infrared (FTIR) spectroscopy and quartz crystal microbalance with dissipation (QCM-D) monitoring technique. The HAp nanocrystals were coated on a gold-coated quartz sensor by electrophoretic deposition. Proteins adsorbed on the HAp sensors were removed by (i) ammonia/hydrogen peroxide mixture (APM), (ii) ultraviolet light (UV), (ii
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