東北大学 · 医学
Waku Hatta教授の研究室は、早期胃がんの内視鏡的治療を中心に、特に内視鏡的粘膜下層剥離術(ESD)後の予後予測や出血リスクの評価に注力しています。特に、がん特異的生存予後を予測するスコアリングシステムや、リンパ節転移のリスクを評価するeCuraシステムの開発を通じて、治療意思決定の支援をめざしています。また、オプト体断層撮影(OCT)を用いた腫瘍の前治療ステージングの可能性や、神経内分泌腫瘍の転移リスク要因の解明など、診断技術の高度化にも貢献しています。
Figures are computed from collected data and may differ slightly.
This scoring system predicted cancer-specific survival in patients who did not meet the curative criteria after ESD for EGC. ESD without additional treatment may be an acceptable option for patients at low risk.
In this nationwide multicentre study, we derived and externally validated a prediction model for bleeding after ESD. This model may be a good clinical decision-making support tool for ESD in patients with EGC.
Japanese guidelines for gastric cancer treatment were first published in 2001 for the purpose of showing the appropriate indication for each treatment method, thereby reducing differences in the therapeutic approach among institutions, and so on. With the accumulation of evidence and the development and prevalence of endoscopic submucosal dissection (ESD), the criteria for the indication and curability of endoscopic resection (ER) for early gastric cancer (EGC) have expanded. However, several pr
To our knowledge, this is the first study demonstrating that OCT might be useful for the preoperative staging of SESCCs with a high degree of accuracy.
Esophagogastric junction (EGJ) adenocarcinoma has been on the increase in Western countries. However, in Asian countries, data on the incidence of EGJ adenocarcinoma are evidently lacking. In the present review, we focus on the current clinical situation of EGJ adenocarcinoma in three Asian countries: Japan, Hong Kong, and Malaysia. The incidence of EGJ adenocarcinoma has been reported to be gradually increasing in Malaysia and Japan, whereas it has stabilized in Hong Kong. However, the number o
This is the first study to demonstrate the risk factors of metastasis in NAD-NETs ≤20 mm in diameter. These findings may be helpful for determining the appropriate therapeutic approach and the clinical strategy of treatment following ER.
We prospectively demonstrated that the preoperative staging of SESCC by using OCT was more useful than that by using EUS.
This is the first study to demonstrate the detailed association between cigarette smoking and metachronous gastric cancer development.
The combined assessment of multiple predictors might help to predict early and/or late mortality in patients with EGCs. The eCura system was associated with early mortality.
We could predict the acid secretion status based on the endoscopic findings regardless of H. pylori infection status, which would be of some help for evaluating the risk for acid-related diseases.
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