京都大学 · 医学
Yuki Muraoka教授の研究室では、眼底疾患の病態解明と画像診断技術の高度化を柱として、特にOCT（光学コherenceトモグラフィ）を用いた網膜・脈絡膜の微細構造解析に注力しています。特に、中心性せん毛症（CSC）における傍中心静脈の異常や、高次元の眼内構造の変化を高分解能で可視化することで、疾患の発症メカニズムの解明を進めています。また、網膜静脈閉塞症などの循環障害性網膜疾患においても、画像所見と視機能の関連を精査し、治療効果の予測可能性を高める研究が展開されています。
Figures are computed from collected data and may differ slightly.
Enhanced depth imaging of SS-OCT facilitated the analysis of WF changes in choroidal thickness in both healthy patients and patients with CSC. The local factors of the affected vortex vein and systemic risk factors may be involved in the pathogenesis of CSC.
Paravascular inner retinal defects primarily occur in eyes with high myopia or epiretinal membrane. Deviated retinal vessels due to axial elongation or epiretinal membrane traction may be involved in the pathogenesis. Paravascular inner retinal defects often cause retinal dysfunction corresponding to the location. A PIRD may partially overlap with retinal lesions previously reported as cleavage of the retinal nerve fiber layer, inner retinal cleavage, paravascular retinal cysts, or lamellar hole
In eyes with CRVO, OCT can be used to visualize anteroposterior venous tortuosity and associated structural changes to the retinal parenchyma.
To investigate the functional and morphologic prognoses of eyes with subfoveal hemorrhage from acute branch retinal vein occlusion (BRVO), and to examine the effect of intravitreal ranibizumab injection (IVR) on these prognoses, we assessed 81 eyes with acute BRVO, of which 38 did not receive IVR [IVR(-) group], and 43 were treated with IVR [IVR(+) group] for macular edema. The foveal morphologic changes were examined via optical coherence tomography (OCT). At initial examination, 63 eyes exhibi
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