Sungkyunkwan University · Medicine
Yun-Hee Kim 교수의 연구실은 뇌의 신경가소성과 인지 기능 향상을 위한 비침습적 뇌자극 기술, 특히 rTMS와 tDCS를 활용한 뇌기능 조절 연구에 주력하고 있습니다. 뇌졸중 및 뇌손상 환자를 대상으로 한 신경재활 및 인지기능 향상에 초점을 맞춘 임상적 응용 연구를 지속적으로 수행하고 있으며, 동시에 3차원 이미징 기술의 혁신적 개선을 위한 기술적 연구도 함께 진행하고 있습니다.
Figures are computed from collected data and may differ slightly.
High-frequency rTMS of the affected motor cortex can facilitate practice-dependent plasticity and improve the motor learning performance in chronic stroke victims.
The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed before, during, and 30 min after 1 mA anodal or sham tDCS. Anodal tDCS, compared with sham stimulation, significantly improved working-memory performance. Accuracy of response was signi
Our results demonstrated that anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex was associated with enhanced working memory performance as indexed by the recognition accuracy in patients after a stroke.
These findings demonstrate the plasticity and training induced redistribution of the visuospatial attentional network in TBI patients.
We propose an enhanced three-dimensional integral imaging system using a curved lens array. Incorporation of a curved lens array instead of a conventional flat lens array expands the viewing angle remarkably. The flipped images are eliminated effectively by adopting barriers. The principle of the proposed system is explained and the experimental results are also presented.
A wide-viewing-angle integral three-dimensional imaging system made by curving a screen and a lens array is described. A flexible screen and a curved lens array are incorporated into an integral imaging system in place of a conventional flat display panel and a flat lens array. One can effectively eliminate flipped images by adopting barriers. As a result, the implemented system permits the limitation of viewing angle to be overcome and the viewing angle to be expanded remarkably. Using the prop
A resolution and viewing-angle enhanced integral imaging system using electrically movable pinhole array is proposed. A pinhole array on liquid crystal is adopted as dynamic pinhole array in integral imaging. The location of the pinhole array is controlled electrically. The pinhole array is expected to be moved fast enough to make an after-image effect, and the corresponding elemental images are displayed synchronously without reducing the 3D viewing aspect of the reconstructed image. With the p
We synthesized stable Au−Cu2S core−shell-type hybrid nanocrystals, in which the spherical Au core encapsulates in the disk-type Cu2S nanocrystals (avg. size = 7 ± 1 nm), using the simple in situ solvothermal growth of Cu2S on Au nanoparticle seeds. Binding energy and band gap measurement provides evidence for the electron withdrawal of the Au core from the Cu2S shell. The Au encapsulation enhances the visible-light-driven photocatalytic degradation yield of methylene blue and rhodamine B dyes. I
Autoreactive T lymphocytes probably cause pancreatic beta-cell death by inducing apoptosis. To visualize apoptotic beta-cells in vivo, we accelerated diabetes of NOD mice with cyclophosphamide (CY) or adoptive transfer. We also studied whether Fas-mediated apoptosis is involved in the development of diabetes by administrating anti-Fas ligand (FasL) Ab and by grafting Fas-deficient neonatal pancreas from NOD-lpr/lpr mice. Apoptotic cells were clearly shown 8 days after CY treatment. Beta-cell apo
This fMRI study was undertaken to test whether the pathophysiological mechanism of mirror movements in hemiparetic stroke patients involves activation of the unaffected motor cortex. We studied 16 control subjects and 51 stroke patients. fMRI was performed at 1.5 T using a finger flexion-extension movement paradigm. The incidence of bilateral primary sensorimotor cortex activation was significantly increased during movements of the affected hand of stroke patients who showed mirror movements. Mo
The administration of single-dose methylphenidate has an effect in improving cognitive functioning following a TBI. The effects were most prominent regarding the reaction time of the working memory.
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