Zhicheng Yuan

Receptor for advanced glycation end products (RAGE) is implicated in inflammatory responses in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), but its role in pulmonary edema formation remains unclear, especially in infection-related ARDS mainly caused by pneumonia or sepsis. In this study, we investigated the role of RAGE in alveolar fluid regulation by using RAGE gene knockout (RAGE) mice in a murine ALI model induced by lipopolysaccharide (LPS), and by comparing soluble RA

Direct numerical simulation is employed to study the behaviors of droplets impinging a surface with a wettability difference. Unlike the four stages of a droplet passing through on homogeneous surfaces, results illustrate that the droplet undergoes asymmetric spreading, retracting, detaching, and self-migrating phases when it impacts the surface with nonuniform decorations. This happens because of the unbalanced Young's force acting on the three-phase contact line around the drop periphery, whic

In this paper, the control of multiple ships for unknown scalar field source seeking problem with unknown external disturbances is considered. The sliding mode active disturbance rejection observers are designed first to converge to fixed multiple of the unknown external disturbances in finite time, respectively, and a least square method is adopted to estimate the gradient of the unknown scalar field at the position of the leading ship. Second, the surge, sway and angle velocity of the leading

Mitochondrial damage-associated molecular patterns exacerbate lung fluid imbalance in the experimental acute lung injury model through formyl peptide receptor-1 signaling, the inhibition of which may prevent exacerbation of lung fluid imbalance induced by mitochondrial damage-associated molecular patterns. Thus, formyl peptide receptor-1 is a potential therapeutic target for acute respiratory distress syndrome.

The hydrophobicity of low-energy surfaces is frequently enhanced by masking with micro-structures. However, wetting transition from the Cassie state (total non-wetting state) to the Wenzel state (total wetting state), which often occurs under external factors, such as impingement and vibration, is known to weaken the water repellency, namely, the hydrophobicity of these textured surfaces. The present work numerically examines the stability of the total non-wetting state on the multi-hole surface

Spherical robot has good potential for complex environment adaptation, but the single internal driving principle limits its multifaceted performance. In this paper, we present a composite driving principle which uses pendulum and momentum wheels. The abilities to change motion state and surmount obstacles have been improved. This article also contains the dynamic analysis and a controller of this driving principle. Finally, we implement necessary simulations and experiments to prove the performa

<b>Background:</b> Injury releases mitochondrial 9damage9-associated molecular patterns （mitochondrial DAMPs；MTDs）into the circulation with functionally important immune consequences，and acute respiratory distress syndrome is characterized with uncontrolled lung inflammation. However, the role of MTDs in acute lung injury(ALI) still remains unclear. <b>Methods:</b> Bronchoalveolar lavage fluid (BALF) and serum levels of NADH-ubiquinone oxidoreductase chain 1 (ND-1)and albumin in ARDS patients an

In space missions, particularly in on-orbit servicing (OOS) missions, many tasks involve non-cooperative targets. To ensure the safety and precision of such missions, complete identification of the target’s inertia parameters is essential. This paper proposes a novel method for identifying the inertia parameters of a non-cooperative target, introducing an innovative approach to position and velocity estimation based on a time-of-flight (TOF) camera. The paper first describes the physical configu

The hydrophobicity of low-energy surfaces is frequently enhanced by masking with micro-structures. However, wetting transition from the Cassie state (total non-wetting state) to the Wenzel state (total wetting state), which often occurs under external factors, such as impingement and vibration, is known to weaken the water repellency, namely, the hydrophobicity of these textured surfaces. The present work numerically examines the stability of the total non-wetting state on the multi-hole surface