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윤보라 교수

Bo La Yun

서울대학교 · 의학

연구실 소개

윤보라 교수의 연구실은 유방암의 조기 진단 및 정밀 진료를 위한 영상의학 기반 기술 개발에 주력하고 있습니다. 특히 초음파, MRI, CT를 활용한 암의 조기 탐지 및 종양 생물학적 특성과의 연관성 분석, 그리고 표적 치료를 위한 나노입자 기반 약물 전달 시스템 개발에 초점을 맞추고 있습니다. 특히, 영상 소견과 분자형질 간의 상관관계를 규명하고, 임상적 의사결정 지원을 위한 컴퓨터 보조 진단 시스템의 정밀도 향상에도 기여하고 있습니다.

유방암 영상진단표적 약물 전달나노입자MRI 분석컴퓨터 보조 진단

연구 현황

논문 수
89
총 인용 수
1,852
최근 5년 논문
20
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
20총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
184총합
20212022202320242025

주요 논문

15
1
논문|인용수 171·2013
Breast Cancer Detected with Screening US: Reasons for Nondetection at Mammography
Min Sun Bae, Woo Kyung Moon, Jung Min Chang, Hye Ryoung Koo, Won Hwa Kim, Nariya Cho, Ann Yi, Bo La Yun, Su Hyun Lee, Mi Young Kim, Eun Bi Ryu, Mirinae Seo
SJR Q1FWCI 7.3Radiology

Most breast cancers (81%) detected at screening US were not seen at mammography, even in retrospect. In addition, 19% had subtle or evident findings missed at mammography.

Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 164·2009
Distinguishing Tumefactive Demyelinating Lesions from Glioma or Central Nervous System Lymphoma: Added Value of Unenhanced CT Compared with Conventional Contrast-enhanced MR Imaging
Dae Sik Kim, Dong Gyu Na, Keon Ha Kim, Ji‐hoon Kim, Eunhee Kim, Bo La Yun, Kee‐Hyun Chang
SJR Q1FWCI 2.5Radiology

Unenhanced CT plus MR imaging was more accurate for distinguishing TDLs from glioma or CNS lymphoma than contrast-enhanced MR imaging alone.

GeneticsMedicine
3
논문|인용수 147·2012
Correlation of perfusion parameters on dynamic contrast‐enhanced MRI with prognostic factors and subtypes of breast cancers
Hye Ryoung Koo, Nariya Cho, In Chan Song, Hyeonjin Kim, Jung Min Chang, Ann Yi, Bo La Yun, Woo Kyung Moon
SJR Q1FWCI 7.2Journal of Magnetic Resonance Imaging

Breast cancers with higher K(trans) and k(ep) , or lower v(e) , had poor prognostic factors and were often of the triple-negative subtype.

Radiology, Nuclear Medicine and ImagingMedicine
4
논문|인용수 89·2019
A computer-aided diagnosis system using artificial intelligence for the diagnosis and characterization of breast masses on ultrasound
Hee Jeong Park, Sun Mi Kim, Bo La Yun, Mijung Jang, Bohyoung Kim, Ja Yoon Jang, Jong Yoon Lee, Soo Hyun Lee
SJR Q3FWCI 7.8MedicineOA

To evaluate the value of the computer-aided diagnosis (CAD) program applied to diagnostic breast ultrasonography (US) based on operator experience.US images of 100 breast masses from 91 women over 2 months (from May to June 2015) were collected and retrospectively analyzed. Three less experienced and 2 experienced breast imaging radiologists analyzed the US features of the breast masses without and with CAD according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon and categorie

Artificial IntelligenceComputer Science
5
논문|인용수 85·2011
Sonoelastography for 1786 non-palpable breast masses: diagnostic value in the decision to biopsy
Ann Yi, Nariya Cho, Jung Min Chang, Hye Ryoung Koo, Bo La Yun, Woo Kyung Moon
SJR Q1FWCI 7.1European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
6
논문|인용수 60·2018
Prediction of Subclinical Coronary Artery Disease With Breast Arterial Calcification and Low Bone Mass in Asymptomatic Women
Yeonyee E. Yoon, Kyoung Min Kim, Jong Soo Han, Si‐Hyuck Kang, Eun Ju Chun, Soyeon Ahn, Sun Mi Kim, Sang Il Choi, Bo La Yun, Jung‐Won Suh
SJR Q1FWCI 4.5JACC. Cardiovascular imaging
Radiology, Nuclear Medicine and ImagingMedicine
7
논문|인용수 58·2014
Trastuzumab-Conjugated Liposome-Coated Fluorescent Magnetic Nanoparticles to Target Breast Cancer
Mijung Jang, Young Il Yoon, Yong‐Su Kwon, Tae‐Jong Yoon, Hak Jong Lee, Sung Il Hwang, Bo La Yun, Sun Mi Kim
SJR Q1FWCI 3.4Korean Journal of RadiologyOA

Trastuzumab-conjugated Lipo[MNP@m-SiO2] is a potential treatment tool for targeted drug delivery in Her2/neu-positive breast cancer.

BiomaterialsMaterials Science
8
논문|인용수 57·2018
Benign Intraductal Papilloma without Atypia on Core Needle Biopsy Has a Low Rate of Upgrading to Malignancy after Excision
Song-Hee Han, Milim Kim, Yul Ri Chung, Bo La Yun, Mijung Jang, Sun Mi Kim, Eunyoung Kang, Eun‐Kyu Kim, So Yeon Park
SJR Q2FWCI 4.8Journal of Breast CancerOA

The rate of upgrading to malignancy for benign IDP without atypia was very low, suggesting that close clinical and radiologic observation may be sufficient for patients with benign IDP without atypia on CNB under proper settings.

Pathology and Forensic MedicineMedicine
9
논문|인용수 52·2019
Benign Breast Papilloma without Atypia: Outcomes of Surgical Excision versus US-guided Directional Vacuum-assisted Removal or US Follow-up
Hye Young Choi, Sun Mi Kim, Mijung Jang, Bo La Yun, Eunyoung Kang, Eun‐Kyu Kim, So Yeon Park, Bohyoung Kim, Nariya Cho, Woo Kyung Moon
SJR Q1FWCI 3.5Radiology

Background Recent studies suggest that US-guided directional vacuum-assisted removal (DVAR) is a satisfactory alternative to surgery for benign papilloma of the breast and recommend discretionary diagnostic US follow-up without intervention. Purpose To compare the outcomes of benign papilloma without atypia diagnosed with core needle biopsy (CNB) in patients who underwent US-guided DVAR, US follow-up without intervention, or surgery. Materials and Methods This retrospective review included conse

Pathology and Forensic MedicineMedicine
10
논문|인용수 48·2017
The Management Strategy of Benign Solitary Intraductal Papilloma on Breast Core Biopsy
Dayoung Ko, Eunyoung Kang, So Yeon Park, Sun Mi Kim, Mijung Jang, Bo La Yun, Sumin Chae, Yerang Jang, Hye Jin Kim, Sung‐Won Kim, Eun-Kyu Kim
SJR Q2FWCI 4.4Clinical Breast Cancer
Pathology and Forensic MedicineMedicine
11
논문|인용수 45·2019
Additive value of diffusion‐weighted MRI in the I‐SPY 2 TRIAL
Wen Li, David C. Newitt, Lisa J. Wilmes, Ella F. Jones, Vignesh A. Arasu, Jessica Gibbs, Bo La Yun, Elizabeth Li, Savannah C. Partridge, John Kornak, Laura J. Esserman, Nola M. Hylton
SJR Q1FWCI 4.6Journal of Magnetic Resonance ImagingOA

2 Technical Efficacy Stage: 4 J. Magn. Reson. Imaging 2019;50:1742-1753.

Radiology, Nuclear Medicine and ImagingMedicine
12
논문|인용수 43·2022
Microcalcifications and Peritumoral Edema Predict Survival Outcome in Luminal Breast Cancer Treated with Neoadjuvant Chemotherapy
Bo Ra Kwon, Sung Ui Shin, Soo‐Yeon Kim, Yunhee Choi, Nariya Cho, Sun Mi Kim, Ann Yi, Bo La Yun, Mijung Jang, Su Min Ha, Su Hyun Lee, Jung Min Chang
SJR Q1FWCI 3.8Radiology

Background Little is known regarding findings at imaging associated with survival in patients with luminal breast cancer treated with neoadjuvant chemotherapy (NAC). Purpose To determine the relationship between imaging (MRI, US, and mammography) and clinical-pathologic variables in predicting distant metastasis-free survival (DMFS) and overall survival (OS) in patients with luminal breast cancer treated with NAC. Materials and Methods In this retrospective study, consecutive women with luminal

Cancer ResearchBiochemistry, Genetics and Molecular Biology
13
논문|인용수 30·2014
Intratumoral Heterogeneity of Breast Cancer Xenograft Models: Texture Analysis of Diffusion-Weighted MR Imaging
Bo La Yun, Nariya Cho, Mulan Li, Min Hye Jang, So Yeon Park, Ho Chul Kang, Bohyoung Kim, In Chan Song, Woo Kyung Moon
SJR Q1FWCI 3.5Korean Journal of RadiologyOA

The texture analysis of ADC maps may help to determine the intratumoral spatial heterogeneity of necrosis patterns, amount of cellular proliferation and the vascularity in MCF-7 and MDA-MB-231 xenograft breast cancer models.

Radiology, Nuclear Medicine and ImagingMedicine
14
논문|인용수 23·2018
Comparison of the Diagnostic Performance of Synthetic Versus Acquired High b‐Value (1500 s/mm<sup>2</sup>) Diffusion‐Weighted MRI in Women With Breast Cancers
Jung Hyun Park, Bo La Yun, Mijung Jang, Hye Shin Ahn, Sun Mi Kim, Soo Hyun Lee, Eunyoung Kang, Eun‐Kyu Kim, So Yeon Park
SJR Q1FWCI 2.0Journal of Magnetic Resonance Imaging

3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:857-863.

Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 17·2011
Radiofrequency Ablation for Treating Liver Metastases from a Non-Colorectal Origin
Bo La Yun, Jeong Min Lee, Ji Hyun Baek, Se Hyung Kim, Jae Young Lee, Joon Koo Han, Byung Ihn Choi
SJR Q1FWCI 0.9Korean Journal of RadiologyOA

RFA showed intermediate therapeutic effectiveness for the treatment of non-colorectal origin liver metastases.

HepatologyMedicine

대표 연구 분야

Radiology, Nuclear Medicine and ImagingPathology and Forensic MedicineCancer ResearchPulmonary and Respiratory MedicineGeneticsArtificial Intelligence

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