윤보라 교수
Bo La Yun
서울대학교 · 의학
연구실 소개
윤보라 교수의 연구실은 유방암의 조기 진단 및 정밀 진료를 위한 영상의학 기반 기술 개발에 주력하고 있습니다. 특히 초음파, MRI, CT를 활용한 암의 조기 탐지 및 종양 생물학적 특성과의 연관성 분석, 그리고 표적 치료를 위한 나노입자 기반 약물 전달 시스템 개발에 초점을 맞추고 있습니다. 특히, 영상 소견과 분자형질 간의 상관관계를 규명하고, 임상적 의사결정 지원을 위한 컴퓨터 보조 진단 시스템의 정밀도 향상에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Most breast cancers (81%) detected at screening US were not seen at mammography, even in retrospect. In addition, 19% had subtle or evident findings missed at mammography.
Unenhanced CT plus MR imaging was more accurate for distinguishing TDLs from glioma or CNS lymphoma than contrast-enhanced MR imaging alone.
Breast cancers with higher K(trans) and k(ep) , or lower v(e) , had poor prognostic factors and were often of the triple-negative subtype.
To evaluate the value of the computer-aided diagnosis (CAD) program applied to diagnostic breast ultrasonography (US) based on operator experience.US images of 100 breast masses from 91 women over 2 months (from May to June 2015) were collected and retrospectively analyzed. Three less experienced and 2 experienced breast imaging radiologists analyzed the US features of the breast masses without and with CAD according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon and categorie
Trastuzumab-conjugated Lipo[MNP@m-SiO2] is a potential treatment tool for targeted drug delivery in Her2/neu-positive breast cancer.
The rate of upgrading to malignancy for benign IDP without atypia was very low, suggesting that close clinical and radiologic observation may be sufficient for patients with benign IDP without atypia on CNB under proper settings.
Background Recent studies suggest that US-guided directional vacuum-assisted removal (DVAR) is a satisfactory alternative to surgery for benign papilloma of the breast and recommend discretionary diagnostic US follow-up without intervention. Purpose To compare the outcomes of benign papilloma without atypia diagnosed with core needle biopsy (CNB) in patients who underwent US-guided DVAR, US follow-up without intervention, or surgery. Materials and Methods This retrospective review included conse
2 Technical Efficacy Stage: 4 J. Magn. Reson. Imaging 2019;50:1742-1753.
Background Little is known regarding findings at imaging associated with survival in patients with luminal breast cancer treated with neoadjuvant chemotherapy (NAC). Purpose To determine the relationship between imaging (MRI, US, and mammography) and clinical-pathologic variables in predicting distant metastasis-free survival (DMFS) and overall survival (OS) in patients with luminal breast cancer treated with NAC. Materials and Methods In this retrospective study, consecutive women with luminal
The texture analysis of ADC maps may help to determine the intratumoral spatial heterogeneity of necrosis patterns, amount of cellular proliferation and the vascularity in MCF-7 and MDA-MB-231 xenograft breast cancer models.
3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:857-863.
RFA showed intermediate therapeutic effectiveness for the treatment of non-colorectal origin liver metastases.
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