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구본욱 교수

Bon-Wook Koo

서울대학교 · 의학

연구실 소개

구본욱 교수의 연구실은 마취 및 수술 중 환자의 안정성과 수술 조건 향상을 목표로 하며, 특히 심층 신경근차단이 복강경 수술 중 수술 조건과 환자 회복에 미치는 영향을 중심으로 연구를 진행하고 있습니다. 신경근차단 수준의 최적화, 수술 중 스트레스 반응 조절, 그리고 인공지능 기반의 통증 예측 모델 개발까지 다각도의 접근을 통해 수술 마취의 과학적 근거를 강화하고 있습니다. 특히 복강경 총창절제술, 담낭절제술 등에서의 신경근차단 전략과 마취 방법이 합병증 예방에 미치는 영향에 초점을 맞추고 있습니다.

심층 신경근차단수술 조건 향상통증 예측마취 전략인공지능 의료

연구 현황

논문 수
74
총 인용 수
802
최근 5년 논문
35
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
35총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
200총합
20212022202320242025

주요 논문

15
1
논문|인용수 71·2016
Randomized Clinical Trial of Moderate Versus Deep Neuromuscular Block for Low‐Pressure Pneumoperitoneum During Laparoscopic Cholecystectomy
Bon‐Wook Koo, Ah‐Young Oh, Kwang‐Suk Seo, Jiwon Han, Ho‐Seong Han, Yoo‐Seok Yoon
SJR Q1FWCI 10.5World Journal of Surgery

The maintenance of intraoperative deep neuromuscular blockade was associated with a lower rate of conversion to standard pressure and higher surgeon satisfaction with the surgical conditions than was moderate blockade in patients undergoing low-pressure pneumoperitoneum laparoscopic cholecystectomy.

Anesthesiology and Pain MedicineMedicine
2
논문|인용수 55·2016
Preventive Analgesic Efficacy of Nefopam in Acute and Chronic Pain After Breast Cancer Surgery
Hyo-Seok Na, Ah‐Young Oh, Bon‐Wook Koo, Dae-Jin Lim, Jung‐Hee Ryu, Ji-Won Han
SJR Q3FWCI 4.7MedicineOA

Breast cancer surgery is known to cause severe acute postoperative pain, which can persist for a long time. We administered nefopam preventively to patients undergoing lumpectomy with axillary lymph node dissection or sentinel lymph node biopsy, and evaluated its efficacy on acute and chronic postoperative pain.Enrolled patients were assigned to the nefopam (n = 41) or the control (n = 42) group. Before initiating the operation, 20 mg of nefopam was given to the patients of the nefopam group, an

SurgeryMedicine
3
논문|인용수 43·2021
Structurally-layered soft magnetic Fe-Si components with surface insulation prepared by shell-shaping selective laser melting
Bonuk Koo, Min-Sun Jang, Yeong Gyun Nam, Sangsun Yang, Ji‐Hun Yu, Yong Ho Park, Jae Won Jeong
SJR Q1FWCI 3.7Applied Surface Science
Mechanical EngineeringEngineering
4
논문|인용수 41·2018
Effects of depth of neuromuscular block on surgical conditions during laparoscopic colorectal surgery: a randomised controlled trial
Bon‐Wook Koo, Ah‐Young Oh, H. S. Na, Hanju Lee, Sung‐Bum Kang, Dong Wook Kim, Kwang‐Suk Seo
SJR Q1FWCI 6.6AnaesthesiaOA

There have been few objective evaluations of the effects of deep neuromuscular blockade on intra-operative conditions. In this prospective randomised controlled study, we evaluated the effects of deep neuromuscular block on surgical conditions during laparoscopic colorectal surgery. Patients were randomly allocated using a computer-generated randomisation code to either moderate (train-of-four count 1-2 maintained and antagonised with neostigmine) or deep (post-tetanic count 1-2 maintained and r

Anesthesiology and Pain MedicineMedicine
5
논문|인용수 26·2016
Surgical site infection after colorectal surgery according to the main anesthetic agent: a retrospective comparison between volatile anesthetics and propofol
Bon‐Wook Koo, Jun-Bo Sim, Hyun-Jung Shin, Duck-Woo Kim, Sung‐Bum Kang, Sang-Hwan Do, Hyo‐Seok Na
SJR Q1FWCI 1.9Korean journal of anesthesiologyOA

The results of this study suggest that intravenous anesthesia may have beneficial effects for reducing SSI in colorectal surgery compared to volatile anesthesia.

SurgeryMedicine
6
논문|인용수 19·2019
Effects of deep neuromuscular blockade on the stress response during laparoscopic gastrectomy Randomized controlled trials
Bon‐Wook Koo, Ah‐Young Oh, Jung‐Hee Ryu, Yea-Ji Lee, Ji-Won Han, Sun Woo Nam, Do-Jung Park, Kwang‐Suk Seo
SJR Q1FWCI 1.6Scientific ReportsOA

Maintaining deep neuromuscular block during surgery improves surgical space conditions. However, its effects on patient outcomes have not been well documented. We examined whether maintaining deep neuromuscular blockade during surgery could decrease the stress response compared to moderate neuromuscular blockade. Patients undergoing laparoscopic gastrectomy were randomly allocated to either the moderate (train-of-four counts of 1-2) or deep (post-tetanic counts of 1-2) neuromuscular blockade gro

Cardiology and Cardiovascular MedicineMedicine
7
논문|인용수 10·2024
Machine learning model of facial expression outperforms models using analgesia nociception index and vital signs to predict postoperative pain intensity: a pilot study
Insun Park, Jae Hyon Park, Jongjin Yoon, Hyo‐Seok Na, Ah‐Young Oh, Jung‐Hee Ryu, Bon‐Wook Koo
SJR Q1FWCI 5.7Korean journal of anesthesiologyOA

The ML model constructed using facial expressions best predicted severe postoperative pain (NRS ≥ 7) and outperformed models constructed from physiological signals.

SurgeryMedicine
8
논문|인용수 10·2022
High-permeability Fe-based soft magnetic composite comprising anisotropic Fe-Si chip fillers
Bonuk Koo, Min-Sun Jang, Jong‐Min Park, Young‐Tae Kwon, Sangsun Yang, Yong Ho Park, Jae Won Jeong
SJR Q1FWCI 0.5Materials CharacterizationOA

Here, we demonstrate a novel hybrid soft magnetic composite (SMC) comprising highly-ductile pure-Fe powders and anisotropic Fe-6.5wt%Si chips to capture both high density and soft magnetic properties including high permeability and low core loss. Thin Fe-6.5wt%Si chips with dimensions of 2 mm × 0.5 mm × 0.04 mm were continuously fabricated through melt spinning using grooved copper wheels, and uniform and dense SiO2 surface insulation coatings on the Fe powders and Fe-Si chips were achieved thro

Electronic, Optical and Magnetic MaterialsMaterials Science
9
논문|인용수 9·2017
Effects of particle size and forming pressure on pore properties of Fe-Cr-Al porous metal by pressureless sintering
Bonuk Koo, Yu-Jeong Yi, Min‐Jeong Lee, Byoung-Kee Kim
SJR Q1FWCI 0.3Metals and Materials International
Materials ChemistryMaterials Science
10
논문|인용수 3·2017
Is neuromuscular blocker needed in children undergoing inguinal herniorrhaphy?
Bon‐Wook Koo, Kyu-Whan Jung, Ah‐Young Oh, Eunyoung Kim, Hyo‐Seok Na, Eun-Su Choi, Kwang‐Suk Seo
SJR Q3MedicineOA

In children aged 1 to 6 years undergoing inguinal herniorhaphy under sevoflurane anesthesia using an I-gel, not using neuromuscular blocker showed similar intraoperative condition and shortened recovery time compared with using neuromouscular blocker.

Anesthesiology and Pain MedicineMedicine
11
논문|인용수 3·2024
Effect of the alveolar recruitment maneuver during laparoscopic colorectal surgery on postoperative pulmonary complications: A randomized controlled trial
Yu Kyung Bae, Sun Woo Nam, Ah‐Young Oh, Bo Young Kim, Bon‐Wook Koo, Jiwon Han, Subin Yim
SJR Q1FWCI 1.3PLoS ONEOA

Intraoperative lung-protective ventilation, including low tidal volume and positive end-expiratory pressure, reduces postoperative pulmonary complications. However, the effect and specific alveolar recruitment maneuver method are controversial. We investigated whether the intraoperative intermittent recruitment maneuver further reduced postoperative pulmonary complications while using a lung-protective ventilation strategy. Adult patients undergoing elective laparoscopic colorectal surgery were

Pulmonary and Respiratory MedicineMedicine
12
리뷰|인용수 3·2025
Comparison of the Safety and Efficacy of Remimazolam and Propofol for Sedation in Adults Undergoing Colonoscopy: A Meta-Analysis of Randomized Controlled Trials
Bon‐Wook Koo, Hyo-Seok Na, Sang-Hi Park, Seunguk Bang, Hyun‐Jung Shin
SJR Q2FWCI 6.6MedicinaOA

<i>Background and Objectives</i>: This meta-analysis evaluates the safety and efficacy of remimazolam versus propofol for sedation during colonoscopy, focusing on hemodynamic and respiratory outcomes. <i>Materials and Methods</i>: A comprehensive search of CENTRAL, Embase, PubMed, Scopus, and Web of Science up to January 2025 identified randomized controlled trials (RCTs). Outcomes included hypotension (primary outcome), bradycardia, respiratory depression, injection pain, sedation onset time, e

Anesthesiology and Pain MedicineMedicine
13
논문|인용수 2·2022
High-Permeability Fe-Based Soft Magnetic Composite Comprising Anisotropic Fe-Si Chip Fillers
Bonuk Koo, Min-Sun Jang, Jongmin Park, Young‐Tae Kwon, Sangsun Yang, Yong Ho Park, Jae‐Weon Jeong
SSRN Electronic JournalOA
Mechanical EngineeringEngineering
14
논문|인용수 2·2015
Fabrication of Fe-Cr-Al Porous Metal with Sintering Temperature and Times
Bonuk Koo, Su-in Lee, Dahee Park, Jung‐Yeul Yun, Byoung-Kee Kim
Journal of Korean Powder Metallurgy Institute

Abstract The porous metals are known as relatively excellent characteristic such as large surface area, light, lowerheat capacity, high toughness and permeability. The Fe-Cr-Al alloys have high corrosion resistance, heat resistance andchemical stability for high temperature applications. And then many researches are developed the Fe-Cr-Al porous met-als for exhaust gas filter, hydrogen reformer catalyst support and chemical filter. In this study, the Fe-Cr-Al porous met-als are developed with Fe

Materials ChemistryMaterials Science
15
논문|인용수 2·2024
Goal-directed fluid therapy on the postoperative complications of laparoscopic hepatobiliary or pancreatic surgery: An interventional comparative study
Bon‐Wook Koo, Ah‐Young Oh, Hyo‐Seok Na, Jiwon Han, Hyun Jung Kim
SJR Q1FWCI 1.1PLoS ONEOA

GDFT based on SV and CI resulted in a lower net fluid balance than conventional fluid therapy. The overall complication rate in laparoscopic hepatobiliary or pancreatic surgery decreased after GDFT, and the frequency of pleural effusion was the most affected.

SurgeryMedicine

대표 연구 분야

SurgeryAnesthesiology and Pain MedicineMechanical EngineeringMaterials ChemistryCritical Care and Intensive Care MedicineCardiology and Cardiovascular Medicine

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