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최병세 교수

Byung Se Choi

서울대학교 · 의학

연구실 소개

최병세 교수의 연구실은 뇌영상학을 기반으로 신경퇴행성질환, 특히 파킨슨병과 α-시나클레오파티의 조기 진단 및 병태생리 기전 규명을 목표로 합니다. 고해상도 MRI를 활용한 니그로솜, 뉴로멜라닌, 철분 분포 및 간질성 간질성 경로 기능 평가 등 정밀 뇌영상 기법 개발에 주력하고 있으며, 특히 DTI를 활용한 뇌간질성 기능 평가와 머신러닝 기반 진단 알고리즘 개발도 진행하고 있습니다. 또한, 수면 장애와 관련된 빠른 눈동자 운동 행동 장애(RBD)에서 뇌간질성 기능 이상이 어떻게 신경퇴행성 질환으로의 전환과 연관되는지 비침습적 영상으로 규명하고자 합니다.

파킨슨병뇌영상학DTI뇌간질성 기능머신러닝 진단

연구 현황

논문 수
136
총 인용 수
2,877
최근 5년 논문
38
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
38총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
632총합
20212022202320242025

주요 논문

15
1
논문|인용수 186·2020
Altered glymphatic system in idiopathic normal pressure hydrocephalus
Yun Jung Bae, Byung Se Choi, Jong‐Min Kim, Ji-Hyun Choi, Se Jin Cho, Jae Hyoung Kim
SJR Q1FWCI 10.3Parkinsonism & Related DisordersOA
Cellular and Molecular NeuroscienceNeuroscience
2
리뷰|인용수 131·2021
Imaging the Substantia Nigra in Parkinson Disease and Other Parkinsonian Syndromes
Yun Jung Bae, Jong‐Min Kim, Chul‐Ho Sohn, Ji-Hyun Choi, Byung Se Choi, Yoo Sung Song, Yoonho Nam, Se Jin Cho, Beomseok Jeon, Jae Hyoung Kim
SJR Q1FWCI 10.0RadiologyOA

Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the midbrain. There are various imaging markers for Parkinson disease. Recent advances in MRI have enabled elucidation of the underlying pathophysiologic changes in the nigral structure. This has contributed to accurate and early diagnosis and has improved disease progression monitoring. This article aims to review recent developments in nigral imaging for Parkinson disease and other parkinsonian syndromes, i

NeurologyMedicine
3
논문|인용수 121·2018
Altered brain function in persistent postural perceptual dizziness: A study on resting state functional connectivity
Jin‐Ok Lee, Eek‐Sung Lee, Ji‐Soo Kim, Young‐Beom Lee, Yong Jeong, Byung Se Choi, Jae‐Hyoung Kim, Jeffrey P. Staab
SJR Q1FWCI 5.3Human Brain MappingOA

This study used resting state functional magnetic resonance imaging (rsfMRI) to investigate whole brain networks in patients with persistent postural perceptual dizziness (PPPD). We compared rsfMRI data from 38 patients with PPPD and 38 healthy controls using whole brain and region of interest analyses. We examined correlations among connectivity and clinical variables and tested the ability of a machine learning algorithm to classify subjects using rsfMRI results. Patients with PPPD showed: (a)

NeurologyNeuroscience
4
리뷰|인용수 115·2020
Brain metastasis detection using machine learning: a systematic review and meta-analysis
Se Jin Cho, Leonard Sunwoo, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Jae Hyoung Kim
SJR Q1FWCI 8.5Neuro-OncologyOA

A comparable detectability of BM with a low false-positive rate per person was found in the DL group compared with the cML group. Improvements are required in terms of quality and study design.

Pulmonary and Respiratory MedicineMedicine
5
논문|인용수 112·2008
Intracranial Stenting of Severe Symptomatic Intracranial Stenosis: Results of 100 Consecutive Patients
Dae Chul Suh, J.K. Kim, Jin Woo Choi, Byung Se Choi, Hae Wook Pyun, Yunseo Choi, M.-H. Kim, Hongna Yang, Hu Ha, S.J. Kim, D.H. Lee, Choong Gon Choi
SJR Q1FWCI 11.4American Journal of NeuroradiologyOA

BEICS revealed a low AE and good outcome rate at 6 months, especially in the stable patients. Midterm outcome was also favorable in the unstable patient group.

Pulmonary and Respiratory MedicineMedicine
6
논문|인용수 106·2018
Deep Learning in Diagnosis of Maxillary Sinusitis Using Conventional Radiography
Youngjune Kim, Kyong Joon Lee, Leonard Sunwoo, Dongjun Choi, Chang-Mo Nam, Jungheum Cho, Jihyun Kim, Yun Jung Bae, Roh‐Eul Yoo, Byung Se Choi, Cheolkyu Jung, Jae Hyoung Kim
SJR Q1FWCI 5.9Investigative Radiology

The deep learning algorithm could diagnose maxillary sinusitis on Waters' view radiograph with superior AUC and comparable sensitivity and specificity to those of radiologists.

OtorhinolaryngologyMedicine
7
논문|인용수 106·2023
Altered Brain Glymphatic Flow at Diffusion-Tensor MRI in Rapid Eye Movement Sleep Behavior Disorder
Yun Jung Bae, Jong‐Min Kim, Byung Se Choi, Nayoung Ryoo, Yoo Sung Song, Yoonho Nam, In‐Young Yoon, Se Jin Cho, Jae Hyoung Kim
SJR Q1FWCI 15.8Radiology

Background Brain glymphatic dysfunction may contribute to the development of α-synucleinopathies. Yet, noninvasive imaging and quantification remain lacking. Purpose To examine glymphatic function of the brain in isolated rapid eye movement sleep behavior disorder (RBD) and its relevance to phenoconversion with use of diffusion-tensor imaging (DTI) analysis along the perivascular space (ALPS). Materials and Methods This prospective study included consecutive participants diagnosed with RBD, age-

Cellular and Molecular NeuroscienceNeuroscience
8
논문|인용수 96·2017
MRI Features and <i>IDH</i> Mutational Status of Grade II Diffuse Gliomas: Impact on Diagnosis and Prognosis
Javier Villanueva-Meyer, Matthew D. Wood, Byung Se Choi, Marc C. Mabray, Nicholas Butowski, Tarık Tihan, Soonmee Cha
SJR Q1FWCI 6.6American Journal of RoentgenologyOA

IDH wild-type grade II DGs are associated with a lower ADC and poor clinical outcomes. Combining IDH mutational status and ADC may allow more accurate prediction of clinical outcomes for patients with grade II DGs.

GeneticsMedicine
9
논문|인용수 80·2003
Differential Diagnosis of Benign and Malignant Intraductal Papillary Mucinous Tumors of the Pancreas: MR Cholangiopancreatography and MR Angiography
Byung Se Choi, Tae Kyoung Kim, Ah Young Kim, Kyung Won Kim, Sung Won Park, Pyo Nyun Kim, Hyun Kwon Ha, Moon-Gyu Lee, Song Cheol Kim
SJR Q1FWCI 1.3Korean Journal of RadiologyOA

Combined MRCP and MRA might be useful for the differential diagnosis of malignant and benign IPMTs of the pancreas.

OncologyMedicine
10
논문|인용수 72·2023
Glymphatic function assessment in Parkinson's disease using diffusion tensor image analysis along the perivascular space
Yun Jung Bae, Jong‐Min Kim, Jong‐Min Kim, Byung Se Choi, Ji-Hyun Choi, Nayoung Ryoo, Yoo Sung Song, Se Jin Cho, Jae Hyoung Kim, Jae Hyoung Kim
SJR Q1FWCI 10.7Parkinsonism & Related DisordersOA
Cellular and Molecular NeuroscienceNeuroscience
11
리뷰|인용수 70·2013
Brainstem Pathways for Horizontal Eye Movement: Pathologic Correlation with MR Imaging
Yun Jung Bae, Jae Hyoung Kim, Byung Se Choi, Cheolkyu Jung, Eunhee Kim
SJR Q1FWCI 3.4Radiographics

Horizontal eye movements are conducted by the medial rectus and the lateral rectus muscles, which are innervated by the oculomotor nerve (cranial nerve III) and the abducens nerve (cranial nerve VI), respectively. The oculomotor and the abducens nuclei are interconnected by a tract in the brainstem named the medial longitudinal fasciculus (MLF). Through the MLF, the actions of the oculomotor and the abducens nuclei are coordinated, generating conjugate horizontal eye movements. The disorders of

Pathology and Forensic MedicineMedicine
12
논문|인용수 65·2010
High-Resolution 3D MR Imaging of the Trochlear Nerve
Byung Se Choi, J.H. Kim, Cheolkyu Jung, Jeong‐Min Hwang
SJR Q1FWCI 3.0American Journal of NeuroradiologyOA

The trochlear nerve was visualized 100% of the time on high-resolution imaging with a voxel smaller than the nerve diameter. High-resolution imaging should have an important role in investigating the pathogenic mechanism of neuropathic strabismus, such as congenital superior oblique palsy.

Pathology and Forensic MedicineMedicine
13
논문|인용수 56·2017
Computer-aided detection of brain metastasis on 3D MR imaging: Observer performance study
Leonard Sunwoo, Young Jae Kim, Seung Hong Choi, Kwang Gi Kim, Ji Hee Kang, Yeonah Kang, Yun‐Jung Bae, Roh‐Eul Yoo, Jihang Kim, Kyong Joon Lee, Seung-Hyun Lee, Byung Se Choi
SJR Q1FWCI 2.5PLoS ONEOA

CAD as a second reader helps radiologists improve their diagnostic performance in the detection of BM on MR imaging, particularly for less-experienced reviewers.

Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 50·2018
Procedural and clinical outcomes of endovascular recanalization therapy in patients with cancer-related stroke
Seunguk Jung, Cheolkyu Jung, Jae Hyoung Kim, Byung Se Choi, Yun Jung Bae, Leonard Sunwoo, Ho Geol Woo, Jun Young Chang, Beom Joon Kim, Moon‐Ku Han, Hee‐Joon Bae
SJR Q2FWCI 3.2Interventional NeuroradiologyOA

Objective Embolism due to coagulopathy might be the main pathomechanism underlying cancer-related stroke (CRS). CRS patients with a large artery occlusion could be candidates for endovascular recanalization therapy (ERT), although its procedural and clinical outcomes are not well known. This study aimed to investigate the procedural and clinical outcomes of ERT in CRS patients and the characteristics associated with outcomes compared with those of conventional stroke patients. Methods A registry

EpidemiologyMedicine
15
리뷰|인용수 48·2020
Diagnostic performance of neuromelanin-sensitive magnetic resonance imaging for patients with Parkinson’s disease and factor analysis for its heterogeneity: a systematic review and meta-analysis
Se Jin Cho, Yun Jung Bae, Jong‐Min Kim, Donghyun Kim, Sung Hyun Baik, Leonard Sunwoo, Byung Se Choi, Jae Hyoung Kim
SJR Q1FWCI 1.8European Radiology
NeurologyMedicine

대표 연구 분야

NeurologyPulmonary and Respiratory MedicineEpidemiologyGeneticsRadiology, Nuclear Medicine and ImagingCellular and Molecular Neuroscience

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