신창호 교수
Chang Ho Shin
서울대학교 · 의학
연구실 소개
신창호 교수의 연구실은 핵물리학과 임상의학의 융합을 목표로 하며, 주로 고체핵반응을 이용한 핵구조 및 반응성 연구와 함께, 임상에서의 응용 가능한 진단 기술 개발에 주력하고 있습니다. 특히 페어링 진동 모델을 기반으로 한($^{3}$He,p) 반응 실험을 통해 핵의 양성자-중성자 상호작용과 비대칭핵의 성질을 규명하고 있으며, 동시에 바이러스 진단을 위한 다중항체 PCR 기법 개발을 통해 임상적 빠른 진단 체계를 구축하고자 합니다. 이는 진단의 정확성과 효율성을 동시에 햖थ하고자 하는 실용적 연구 성향을 반영합니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
The ($^{3}\mathrm{He},p$) reactions on $^{46}\mathrm{Ti}$, $^{48}\mathrm{Ti}$, $^{52}\mathrm{Cr}$, $^{54}\mathrm{Fe}$, $^{56}\mathrm{Fe}$, $^{58}\mathrm{Ni}$, and $^{60}\mathrm{Ni}$ leading to the ${0}^{+}$ analog states were studied and compared with the ($t,p$) reactions on the same target nuclei and with the predictions of the pairing vibration model.
Arthroscopically assisted reduction and fixation with cannulated screws is an effective and safe surgical option for treating tibial eminence fracture with few complications.
Abstract Background The acetabular index and center-edge angle are widely used radiographic parameters. However, the exact landmarks for measuring these parameters are not clearly defined. Although their measurement is straightforward when the lateral osseous margin of the acetabular roof coincides with the lateral end of the acetabular sourcil, where these two landmarks disagree, recommendations have differed about which landmark should be used. Using a radiographic parameter with high reliabil
The development of a multiplex polymerase chain reaction (PCR) method for rapid and accurate detection and typing of herpes simplex virus type 1 (HSV-1), and type-2 (HSV-2), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) is very important for clinical diagnosis to allow the deliver of therapy as early as possible. Large scale amplifications by multiplex PCR of viral DNA can lower the cost and time for viral diagnosis. In this study, therefore sensitive quadruplex PCR was achieved by optimizi
Level III, therapeutic study.
This study of Koreans who were more than sixty-five years of age showed that the prevalence of carpal tunnel syndrome is similar in patients with and those without radiographic findings of basal joint arthritis of the thumb. We found no correlation between the electrophysiological severity of carpal tunnel syndrome and the severity of basal joint arthritis.
Screw medial hemi-epiphysiodesis can effectively correct caput valgum associated with DDH. However, this technique remains coxa brevis and does not seem to significantly affect acetabular morphology or reduce subluxation.
Background: The detection and identification of pathogenic microorganisms are essential for the treatment of osteoarticular infection. However, obtaining a sufficient amount of specimen from pediatric patients is often difficult. Herein, we aimed to demonstrate the effectiveness of the blood culture bottle (BCB) system in pediatric osteoarticular infections. We hypothesized that our BCB culture method is superior to the conventional swab and tissue culture methods in terms of required specimen s
Revision TKA incidence varied according to age, gender, and hospital and manufacturer volume. This data could inform clinical decisions and healthcare strategies.
Isolated hemihyperplasia and hemihypoplasia can occur as a spectrum of BWS and SRS. Although the accurate differentiation between isolated hemihyperplasia and isolated hemihypoplasia is important in tumor surveillance planning, it is often difficult to clinically differentiate these two diseases without epigenetic tests. Epigenetic tests may play a role in the prediction of LLD, which would aid in treatment planning.
Abstract Metal-ferroelectric-insulator-semiconductor (MFIS) structures including an Al2O3 insulator layer and a SBT ferroelectric film are fabricated with their optimum thicknesses extracted by computer simulation, and then electrical properties of MFIS structures are investigated. In Pt/Al2O3/Si structure, no hysteresis and low leakage current of 7.5 × 10−9A/cm2 have been observed. The MFIS structure, Pt/SBT/Al2O3/Si, shows a memory window width of 1.2 V at an operation voltage of 5 V and a gat
Brugada syndrome, an autosomal dominantly inherited form of ventricular fibrillation, is characterized by ST- segment elevation in leads V1-3 and right bundle-branch block on surface electrocardiogram. It is caused by mutations in the cardiac sodium channel gene, SCN5A, and to the best of our knowledge, there has been no report of this mutation in Korea. Three members of a family were heterozygous for a G to T substitution at the nucleotide position 5851 in exon 28 of the SCN5A gene. This nucleo
PTS was not found to be a risk factor for pediatric TSF in female or male patients in this study.
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