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성창규 교수

Chang Kyu Sung

서울대학교 · 의학

연구실 소개

성창규 교수의 연구실은 의료 영상 기반의 질병 진단 및 치료 기술 개발을 핵심으로 하며, 특히 암 진단을 위한 고해상도 영상 분석과 함께, 나노입자를 활용한 다중 영상법(양방향 영상) 기반 세포 영상 기술에 주력하고 있습니다. 또한 간질환, 신장질환 등에서의 혈류역학적 변화와 영상 소견 간의 연관성을 규명하고, 신뢰도 높은 비침습적 진단 지표를 개발하고 있습니다. 특히 전기자극 기반 간암 치료 기술의 정량적 분석 및 최적화 모델 개발을 통해 임상적 적용 가능성을 높이고자 합니다.

의료영상나노소재혈류역학비침습적 진단전기자극 치료

연구 현황

논문 수
64
총 인용 수
475
최근 5년 논문
13
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
13총합
2020
2023
2024
2025
2026
5개년 연도별 피인용 수
25총합
20202023202420252026

주요 논문

15
1
논문|인용수 51·2015
Angiomyolipoma with minimal fat: differentiation of morphological and enhancement features from renal cell carcinoma at CT imaging
Chang Kyu Sung, See Hyung Kim, Sungmin Woo, Min Hoan Moon, Sang Youn Kim, Seung Hyup Kim, Jeong Yeon Cho
SJR Q3FWCI 5.0Acta Radiologica

CT images with non-round shape without capsule and prolonged enhancements may be used to differentiate AML with minimal fat from RCC.

Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 34·2009
Dual-Modal Nanoprobes for Imaging of Mesenchymal Stem Cell Transplant by MRI and Fluorescence Imaging
Chang Kyu Sung, Kyung Ah Hong, Shunmei Lin, Yuwon Lee, Jinmyung Cha, Jin‐Kyu Lee, Cheol Pyo Hong, Bong Soo Han, Sung Il Jung, Seung Hyup Kim, Kang Sup Yoon
SJR Q1FWCI 1.6Korean Journal of RadiologyOA

MNP@SiO(2)(RITC)-PEG can be a useful contrast agent for stem cell imaging, which is suitable for a bimodal detection by MRI and optical imaging.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
3
논문|인용수 20·2016
Evaluation of factors influencing arterial Doppler waveforms in an in vitro flow phantom
Chang Kyu Sung, Kyoung Ho Lee, Seung Hyup Kim
SJR Q1FWCI 0.8ULTRASONOGRAPHYOA

Resistance and compliance can alter the Doppler waveforms independently. The pulse rate is an extrinsic factor that also influences the RI. The compliance and distal resistance, as well as proximal resistance, influence the pulsus tardus and parvus phenomenon.

Pulmonary and Respiratory MedicineMedicine
4
논문|인용수 18·2019
Physicochemical factors that affect electroporation of lung cancer and normal cell lines
Hong Bae Kim, Seho Lee, Yiming Shen, Pan Dong Ryu, Yunmi Lee, Jong Hoon Chung, Chang Kyu Sung, Ku Youn Baik
SJR Q2FWCI 1.6Biochemical and Biophysical Research Communications
BiotechnologyBiochemistry, Genetics and Molecular Biology
5
논문|인용수 16·2020
Effects of Actin Cytoskeleton Disruption on Electroporation In Vitro
Hong Bae Kim, Seho Lee, Jong Hoon Chung, Seong Nam Kim, Chang Kyu Sung, Ku Youn Baik
SJR Q2FWCI 2.1Applied Biochemistry and Biotechnology
BiotechnologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 13·2016
Histological and Mathematical Analysis of the Irreversibly Electroporated Liver Tissue
Chang Kyu Sung, Hong Bae Kim, Jong Hyun Jung, Ku Youn Baik, Kee Wook Moon, Hyung-Sik Kim, Jeong‐Han Yi, Jong Hoon Chung
SJR Q2FWCI 0.3Technology in Cancer Research & TreatmentOA

Irreversible electroporation has clinically been used to treat various types of cancer. A plan on how to apply irreversible electroporation before practicing is very important to increase the ablation area and reduce the side effects. Several electrical models have been developed to predict the ablation area with applied electric energy. In this experiment, the static relationship between applied electric energy and ablated area was mathematically and experimentally investigated at 10 hours afte

BiotechnologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 9·2006
Urine Attenuation Ratio: A New CT Indicator of Renal Artery Stenosis
Chang Kyu Sung, Jin Wook Chung, Seung Hyup Kim, Jae Hyung Park
SJR Q1FWCI 1.0American Journal of Roentgenology

The urine CT attenuation ratio is a simple and reliable indicator with which to detect and lateralize significant RAS and is a useful adjunct to helical CTA.

Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 3·2008
Grayscale and Doppler Ultrasonographic Findings Reflecting Disease Severity in Autosomal Dominant Polycystic Kidney Disease
Chang Kyu Sung, Seung Hyup Kim, Curie Ahn
SJR Q3FWCI 0.2Journal of Medical UltrasoundOA

The purpose of this study was to identify the ultrasonographic findings that reflected disease severity in patients with autosomal dominant polycystic kidney disease (ADPKD). In 72 patients with ADPKD, resistive indices (RIs) and the severity of ultrasonographic morphologic abnormalities, such as renal severity index (RSI), modified RSI and the sum of bilateral renal size, were measured and correlated with clinical and laboratory findings including the presence of hypertension and serum creatini

GeneticsBiochemistry, Genetics and Molecular Biology
9
논문|인용수 3·2015
Factors influencing the renal arterial Doppler waveform: a simulation study using an electrical circuit model (secondary publication)
Chang Kyu Sung, Bong Soo Han, Seung Hyup Kim
SJR Q1FWCI 0.2ULTRASONOGRAPHYOA

This simulation study using an electrical circuit model led to a better understanding of the renal arterial Doppler waveform and the RI, which may be useful for interpreting Doppler findings in various clinical settings.

Pulmonary and Respiratory MedicineMedicine
10
book chapter|인용수 2·2016
Retroperitoneal Tumors
Chang Kyu Sung, Bohyun Kim, Kyung Chul Moon, Ja Hyeon Ku, Seung Beom Ha
Pulmonary and Respiratory MedicineMedicine
11
논문|인용수 2·2016
Standard vs. reduced-radiation-dose CT in the tracing of the ureter
Chang Kyu Sung, Min Hoan Moon, Hwancheol Son, Sohee Oh, Myoung Seok Lee, Hyunsik Woo
SJR Q1FWCI 0.3Abdominal Radiology
Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 1·2025
Use of Mitochondrial Delayed Luminescence Measurements From Brain Tissue to Optimize Photobiomodulation Prarameters in Alzheimer's Disease Mice
Hong Bae Kim, Chang Kyu Sung
SJR Q2FWCI 1.4Journal of BiophotonicsOA

The therapeutic potential of photobiomodulation (PBM) for Alzheimer's disease (AD) was evaluated by examining β-amyloid accumulation, microglial activation, and memory function. Mitochondrial delayed luminescence (m-DL), an indirect mitochondrial marker, was measured by irradiating 2 J/cm<sup>2</sup> of 808 nm near-infrared light to the exposed brain surface of anesthetized 5XFAD mice. Based on m-DL findings, behavioral PBM was applied transcranially to the intact scalp using the same fluence at

Radiology, Nuclear Medicine and ImagingMedicine
13
논문|인용수 1·2023
Robust Doppler compensation for low frequency underwater communications
Chang Kyu Sung, Patrick Cooper, Daniel La Mela, Tim Cain
SJR Q1FWCI 0.2The Journal of the Acoustical Society of America

Impairment caused by Doppler frequency shift and harsh channel condition distinguish underwater acoustic communications from radio communications. Slow speed of acoustic waves produces relatively high Doppler shift and result in expansion or compression in time samples, which is known as Doppler scaling. In particular, the Doppler scaling causes significant carrier frequency offset (CFO) in orthogonal frequency division modulation (OFDM). To compensate the CFO, it is essential to resample signal

Ocean EngineeringEngineering
14
book chapter|인용수 1·2012
Introduction
Chang Kyu Sung, Jung Suk Sim
FWCI 2.9
Reproductive MedicineMedicine
15
논문|인용수 1·2023
Histological Response to 5 kHz Irreversible Electroporation in a Porcine Liver Model
Hong Bae Kim, Ku Youn Baik, Chang Kyu Sung
SJR Q2FWCI 0.3Technology in Cancer Research & TreatmentOA

Unlike necrosis by thermal ablation, irreversible electroporation (IRE) is known to induce apoptosis by disrupting plasma membrane integrity with electric pulses while preserving the structure of blood vessels and bile ducts in liver tissue without a heat sink effect. This study aimed to investigate thermal damage and histopathological effects in the porcine liver by high-frequency electric pulses (5 kHz) which is much higher than the widely used 1 Hz. The electric field and thermal distribution

BiotechnologyBiochemistry, Genetics and Molecular Biology

대표 연구 분야

Pulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingReproductive MedicineBiotechnologyUrologySurgery

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