정창욱 교수
Chang Wook Jeong
서울대학교 · 의학
연구실 소개
정창욱 교수의 연구실은 우수한 임상 결과를 도출하기 위한 정밀한 수술 평가 및 예측 모델 개발에 초점을 맞추고 있습니다. 특히 반구형 신장경화술(sPCNL)과 Extracorporeal Shock Wave Lithotripsy(SWL)의 성공률을 높이기 위한 점수 체계와 그래픽 노그램을 개발하여 환자 맞춤형 치료 결정을 지원합니다. 또한 만성 프로스타티티스/만성 골반통증 증체후의 치료 전략과 수술 학습 곡선 분석을 통해 임상 실무의 질적 향상을 도모하고 있습니다. 이와 더불어 전립선암 및 기타 유전비뇨계암의 임상적 결과, 삶의 질, 유전적 및 생물표지자 연구를 통합하는 SUPER-GUC 플랫폼을 운영하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The S-ReSC scoring system is easy to use and reproducible. This score accurately predicts the stone-free rate after sPCNL. Furthermore, this score represents the complexity of surgery.
Between two TRUS volumes, TRUS-V1 was shown to be superior to TRUS-V2. In MRI, MRI-EV2 was more accurate than MRI-EV1. However, MRI-PV was the most accurate method. TRUS-V1 and MRI-EV2 could be used instead of MRI-PV in general clinical settings.
Our results demonstrated that the operative learning curve plateau is reached after about 25 cases. We propose that a more appropriate parameter for estimating the operative learning curve is enucleation ratio efficacy, rather than enucleation efficacy.
For a 6-week short-term treatment levofloxacin is more effective than doxazosin for chronic prostatitis/chronic pelvic pain syndrome. In addition, levofloxacin monotherapy was also more effective when compared with the combination therapy.
We constructed and validated nomograms to predict SFR after SWL. To the best of our knowledge, these are the first graphical nomograms to be modeled with CT information. These may be useful for patient counseling and treatment decision-making.
SUPER-GUC is a study platform for comparative outcome, quality-of-life, and translational (genetics, biomarkers) research for genitourinary cancer.
This is the first study to have developed and fully validated nomograms to predict the pathological stage of prostate cancer in an Asian population. These nomograms might be more accurate and useful for Korean men than other predictive models developed using Western populations.
One-step posterior reconstruction did not significantly shorten time to complete continence recovery. However, it seemed to have a marginal benefit on early recovery of social continence.
During a 3-year period, we successfully treated all patients who had severe immediate postoperative bleeding after radical prostatectomy with TAE. We concluded that rapid diagnosis by CT angiography and early TAE could replace surgical exploration in this situation. In addition, this could minimize the morbidity associated with severe bleeding, transfusion, and open surgical exploration.
The joint forces of first-generation articulating instruments for laparoendoscopic single-site surgery are not sufficient to meet the usual operative needs. Improved articulating instruments with greater articulating forces should be developed.
SNUPC-RC has a higher predictive accuracy and clinical benefit than Western risk calculators. Furthermore, it is easy to use because it is available as a mobile application for smart devices.
대표 연구 분야
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