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한동석 교수

Dong Seok Han

서울대학교 · 의학

연구실 소개

한동석 교수의 연구실은 위암 치료의 정밀화를 목표로 하며, D2 위절제술 후 생존 예측을 위한 노모그램 개발과 M1 위암 환자에서의 항암치료 반응에 따른 예후 분석 등 개인화된 의료 전략 수립에 초점을 맞추고 있습니다. 또한 내 endoscopic 치료법의 유효성 평가 및 위암의 조직학적 분류 기준 개선을 위한 기초 연구도 병행하고 있습니다. 특히, 난세포의 발달 능력과 산화 스트레스 관련 메커니즘에 대한 연구를 통해 생식세포 생존율 향상 전략을 모색하고 있습니다.

위암 예후개인화된 치료노모그램난세포 발달항암치료 반응

연구 현황

논문 수
33
총 인용 수
967
최근 5년 논문
12
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
12총합
2020
2021
2022
2024
2025
5개년 연도별 피인용 수
79총합
20202021202220242025

주요 논문

15
1
논문|인용수 355·2012
Nomogram Predicting Long-Term Survival After D2 Gastrectomy for Gastric Cancer
Dong‐Seok Han, Yun‐Suhk Suh, Seong‐Ho Kong, Hyukjoon Lee, Yunhee Choi, Susumu Aikou, Takeshi Sano, Byung‐Joo Park, Woo Ho Kim, Han‐Kwang Yang
SJR Q1FWCI 7.1Journal of Clinical OncologyOA

We developed a nomogram predicting 5- and 10-year overall survival after D2 gastrectomy for gastric cancer. Validation using the SNUH and CIAH data sets revealed good discrimination and calibration, suggesting good clinical utility. The nomogram improved individualized predictions of survival.

Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 139·2013
Laparoscopy-Assisted Pylorus-Preserving Gastrectomy Is Better Than Laparoscopy-Assisted Distal Gastrectomy for Middle-Third Early Gastric Cancer
Yun‐Suhk Suh, Dong‐Seok Han, Seong‐Ho Kong, Sebastianus Kwon, Cheong‐Il Shin, Woo Ho Kim, Hyung‐Ho Kim, Hyuk‐Joon Lee, Han‐Kwang Yang
SJR Q1FWCI 8.5Annals of Surgery

For middle-third EGC, LAPPG can be considered as a better treatment option than LADG in terms of nutritional advantage and lower incidence of gallstone.

Pulmonary and Respiratory MedicineMedicine
3
논문|인용수 107·2012
Should Adenocarcinoma of the Esophagogastric Junction Be Classified as Esophageal Cancer? A Comparative Analysis According to the Seventh AJCC TNM Classification
Yun‐Suhk Suh, Dong‐Seok Han, Seong‐Ho Kong, Hyukjoon Lee, Young Tae Kim, Woo Ho Kim, Kuhn Uk Lee, Han‐Kwang Yang
SJR Q1FWCI 11.2Annals of Surgery

To evaluate the postoperative prognosis of AEJ within the stomach, AEJ II and AEJ III should be considered a part of gastric cancer irrespective of EGJ involvement.

SurgeryMedicine
4
논문|인용수 78·2018
Effect of perioperative oral nutritional supplementation in malnourished patients who undergo gastrectomy: A prospective randomized trial
Seong‐Ho Kong, Hyukjoon Lee, Ju-ri Na, Won Gyoung Kim, Dong‐Seok Han, Shin‐Hoo Park, Hyunsook Hong, Yunhee Choi, Hye Seong Ahn, Yun‐Suhk Suh, Han‐Kwang Yang
SJR Q1FWCI 3.3Surgery
PhysiologyMedicine
5
논문|인용수 65·2014
Comparison of Surgical Outcomes of Robot-Assisted and Laparoscopy-Assisted Pylorus-Preserving Gastrectomy for Gastric Cancer: A Propensity Score Matching Analysis
Dong‐Seok Han, Yun‐Suhk Suh, Hye Seong Ahn, Seong‐Ho Kong, Hyuk‐Joon Lee, Woo Ho Kim, Han‐Kwang Yang
SJR Q1FWCI 4.1Annals of Surgical Oncology
Pulmonary and Respiratory MedicineMedicine
6
논문|인용수 50·2012
Outcomes of surgery aiming at curative resection in good responder to induction chemotherapy for gastric cancer with distant metastases
Dong‐Seok Han, Yun‐Suhk Suh, Seong‐Ho Kong, Hyuk‐Joon Lee, Seock‐Ah Im, Yung‐Jue Bang, Wooho Kim, Han‐Kwang Yang
SJR Q1FWCI 1.0Journal of Surgical Oncology

The present study provides evidence that in patients with M1 gastric cancer which confined to one site who respond well to induction chemotherapy, a higher rate of R0 resection and longer survival can be expected. A multicenter cohort study is needed to explore this concept further.

Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 36·2020
Prognostic perspectives of PD-L1 combined with tumor-infiltrating lymphocytes, Epstein-Barr virus, and microsatellite instability in gastric carcinomas
Euno Choi, Mee Soo Chang, Sun‐ju Byeon, Heejin Jin, Kyeong Cheon Jung, Haeryoung Kim, Kook Lae Lee, Won Kim, Jin Hyun Park, Ki Hwan Kim, Jin‐Soo Kim, In Sil Choi
SJR Q2FWCI 2.3Diagnostic PathologyOA

Abstract Background The prognostic potential of PD-L1 is currently unclear in gastric carcinomas, although the immune checkpoint PD-1/PD-L1 inhibitors have produced promising results in clinical trials. Methods We explored the prognostic implications of programmed death ligand 1 (PD-L1) in 514 consecutive surgically-resected gastric carcinomas. Overall survival and recurrence-free survival were evaluated. Immunohistochemistry for PD-L1, CD8, FOXP3, and PD-1, and molecular grouping by in situ hyb

OncologyMedicine
8
논문|인용수 28·2015
Preoperative neutrophil-to-lymphocyte ratio is a prognostic factor for overall survival in patients with gastric cancer
Jeong Hwan Kim, Dong‐Seok Han, Ho Yoon Bang, Pyeong Su Kim, Kyung-Yung Lee
SJR Q2FWCI 2.2Annals of Surgical Treatment and ResearchOA

Our study verified that advanced stage, high preoperative NLR (NLR ≥ 1.7), and old age (≥ 70 years) are significant, independent prognostic factor for overall survival in patients with gastric cancer.

OncologyMedicine
9
논문|인용수 23·2008
Protocol Optimization for Long‐Term Liquid Storage of Goat Semen in a Chemically Defined Extender
B‐T Zhao, Dong‐Seok Han, C‐L Xu, M‐J Luo, Z.-L. Chang, J‐H Tan
SJR Q2FWCI 0.4Reproduction in Domestic Animals

A specific problem in the preservation of goat semen has been the detrimental effect of seminal plasma on the viability of spermatozoa in extenders containing egg yolk or milk. The use of chemically defined extenders will have obvious advantages in liquid storage of buck semen. Our previous study showed that the self-made mZAP extender performed better than commercial extenders, and maintained a sperm motility of 34% for 9 days and a fertilizing potential for successful pregnancies for 7 days. T

Reproductive MedicineMedicine
10
리뷰|인용수 22·2018
Evidence-Based Practice Guideline for Surgical Treatment of Gastroesophageal Reflux Disease 2018
Ho Seok Seo, Miyoung Choi, Sang‐Yong Son, Min Gyu Kim, Dong‐Seok Han, Han Hong Lee
SJR Q1FWCI 2.2Journal of the Korean Gastric Cancer AssociationOA

The prevalence of gastroesophageal reflux disease (GERD) is increasing in Korea, and physicians, including surgeons, have been focusing on its treatment. Indeed, in Korea, medical treatment using a proton pump inhibitor is the mainstream treatment for GERD, while awareness of surgical treatment is limited. Accordingly, to promote the understanding of surgical treatment for GERD, the Korean Anti-Reflux Surgery Study Group published the Evidence-Based Practice Guideline for the Surgical Treatment

GastroenterologyMedicine
11
논문|인용수 20·2021
Are the elderly patient's changes in the health-related quality of life one year after gastrectomy for stomach cancer different from those in young patients?
Dong‐Seok Han, Jaeil Ahn, Hye Seong Ahn
SJR Q2FWCI 2.3Annals of Surgical Treatment and ResearchOA

Elderly patients' global health status/quality of life and social functioning significantly decreased at postoperative 1 month and recovered by 6 months after gastrectomy. There was a significant age-specific difference in physical functioning throughout the 1-year follow-up. Surgeons need to pay more attention to recovery of the elderly patients' HRQoL after gastrectomy.

Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 8·2024
Effector Function Characteristics of Exhausted CD8+ T-Cell in Microsatellite Stable and Unstable Gastric Cancer
Dong‐Seok Han, Yoonjin Kwak, Seung‐Ho Lee, Soo Kyung Nam, Seong-Ho Kong, Do Joong Park, Hyuk‐Joon Lee, Nak‐Jung Kwon, Hye Seung Lee, Han‐Kwang Yang
SJR Q1FWCI 1.9Cancer Research and TreatmentOA

Our study reveals novel finding indicating that IFN-γ signaling pathway is retained in Tex and pTex of MSI-H gastric cancer, offering a comprehensive perspective for future investigations into immunotherapy for gastric cancer.

ImmunologyImmunology and Microbiology
13
논문|인용수 7·2021
Comparing the surgical outcomes of dual-port laparoscopic distal gastrectomy and three-port laparoscopic distal gastrectomy for gastric cancer
Hye Seong Ahn, Mee Soo Chang, Dong‐Seok Han
SJR Q2FWCI 1.0Annals of Surgical Treatment and ResearchOA

The surgical outcomes of DPLDG and TPLDG did not differ. Regarding fewer incisions, DPLDG can be an alternative option for TPLDG.

Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 5·2017
사회연결망분석을 활용한 건축계획 분야 공저자 네트워크 분석
윤병의, 김태석, 박종모, 박유진, 김진호, 한동석
대한건축학회논문집

Research activities are being carried out through many collaborative writing activities in various disciplines. However, there is minor research on collaborative research in the field of architecture, although meaningful results can be drawn in many ways. Therefore, in this study, we used technology statistics and social network analysis (SNA) to investigate cooperative relationship for collaborative research analysis from the Architectural planning committee of the Korean Institute of Architect

15
논문|인용수 5·2011
보완대체의학에 대한 국내 일차진료의사와 대학 병원 근무 의사의 지식, 태도, 경험에 관한 설문조사
강승완, 하태국, 조병희, 이상철, 한동석, 이경미, 한서경
대한의사협회지

Despite the recent increase in the use of complementary and alternative medicine (CAM)among the general population and patients, little is known about Korean physicians’attitudes about and interest in CAM. We conducted a web-based survey of knowledge, attitude,and experience in CAM among primary care physicians (PCPs) and academic physicians (APs)in Korea. A total of 826 physicians (341 PCPs and 485 APs) responded. Respondents in both groups felt that they were not sufficiently knowledgeable abo

대표 연구 분야

Pulmonary and Respiratory MedicineSurgeryOncologyNutrition and DieteticsPhysiologyReproductive Medicine

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