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이동석 교수

Dong Seok Lee

서울대학교 · 의학

연구실 소개

이동석 교수의 연구실은 심혈관계 질환, 특히 폐동맥고혈압(PAH)과 대사증후군의 병태생리적 기전을 규명하고자 하며, 특히 심장의 좌심실 기능 저하와 폐혈관 병변에 영향을 주는 생물학적 마커 및 약물 치료 전략을 중심으로 연구를 진행하고 있습니다. 비만, 내장지방 축적, 근육량 감소와 같은 대사적 위험 인자들이 대사증후군 예측에 어떻게 영향을 미치는지에 대한 메커니즘 연구도 함께 수행하고 있습니다. 또한, 염증 반응과 면역 조절을 연계한 소장 및 식도 림프종 등의 희귀 악성 종양의 진단 및 치료 전략 개발에도 기여하고 있습니다.

폐동맥고혈압대사증후군심장기능 저하희귀 림프종면역조절

연구 현황

논문 수
43
총 인용 수
292
최근 5년 논문
16
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
16총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
175총합
20212022202320242025

주요 논문

15
1
논문|인용수 32·2022
Adverse events following COVID-19 vaccination in South Korea between February 28 and August 21, 2021: A nationwide observational study
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Yong Jin Jung, Hyoun Woo Kang
SJR Q1FWCI 3.1International Journal of Infectious DiseasesOA

Although there were differences in the frequency of occurrence, various adverse reactions were confirmed in using all 4 COVID-19 vaccines, even with the BNT162b2 (Pfizer-BioNTech) vaccine. Caution is needed, and further research should be continuously conducted.

Infectious DiseasesMedicine
2
논문|인용수 27·2021
Association of obesity, visceral adiposity, and sarcopenia with an increased risk of metabolic syndrome: A retrospective study
Su Hwan Kim, Hyoun Woo Kang, Ji Bong Jeong, Dong Seok Lee, Dong‐Won Ahn, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Sohee Oh, Soon Ho Yoon, Sang Joon Park
SJR Q1FWCI 2.3PLoS ONEOA

Obesity, visceral adiposity, and sarcopenia showed additive effects on MS prediction. Subjects with obesity, visceral adiposity, or sarcopenia were significantly associated with the increased risk of MS after adjustment for multiple confounders. Increasing skeletal muscle and reducing visceral fat may be strategies for the prevention or treatment of MS.

PhysiologyMedicine
3
논문|인용수 15·2022
Significance of digestive symptoms after COVID-19 vaccination: A retrospective single-center study
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Yong Jin Jung, Hyoun Woo Kang
SJR Q1FWCI 1.4The American Journal of Emergency MedicineOA
Infectious DiseasesMedicine
4
논문|인용수 15·2020
Expression of Chemokine CCL28 in Ulcerative Colitis Patients
Dong Seok Lee, Kook Lae Lee, Ji Bong Jeong, Sue Shin, Su Hwan Kim, Ji Won Kim
SJR Q1FWCI 0.7Gut and LiverOA

CCL28 could be useful for diagnosing UC. However, further validations of CCL28 on disease activity and severity are needed.

OncologyMedicine
5
리뷰|인용수 13·2015
Primary esophageal mucosa-associated lymphoid tissue lymphoma diagnosed by using stacked forceps biopsy
Dong Seok Lee, Yongchel Ahn, Dae‐Woon Eom, Su Jin Lee
SJR Q1FWCI 1.2Diseases of the EsophagusOA

Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy alone is difficult. Therefore, surgical biopsy, endoscopic mucosal resection, and endoscopic ultrasound-guided fine-needle aspiration have been used in most cases. Herein, we report a

GastroenterologyMedicine
6
논문|인용수 9·2013
Advanced Gastric Cancer Associated with Disseminated Intravascular Coagulation Successfully Treated with 5-fluorouracil and Oxaliplatin
Dong Seok Lee, Seung‐Jin Yoo, Ho Suk Oh, Eun‐Jung Kim, Kwang Hoon Oh, Sang Jin Lee, Jong Kyu Park, Yongchel Ahn, Dae‐Woon Eom, Heui June Ahn
SJR Q1FWCI 0.5Journal of the Korean Gastric Cancer AssociationOA

Gastric cancer patients with acute disseminated intravascular coagulation experiences a rare but severe complication resulting in a dismal prognosis. We report a case of advanced gastric cancer complicated with disseminated intravascular coagulation with intractable tumor bleeding which was successfully treated with chemotherapy consisting of 5-fluorouracil and oxaliplatin. The patient was a 63-year-old man who complained of abdominal pain, melena, and dyspnea on 24 November 2010. We diagnosed s

Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 8·2014
Severe Gastroparesis following Radiofrequency Catheter Ablation for Atrial Fibrillation: Suggestion for Diagnosis, Treatment, and Device for Gastroparesis after RFCA
Dong Seok Lee, Sang Jin Lee
FWCI 0.4Case Reports in Gastrointestinal MedicineOA

Gastroparesis following radiofrequency catheter ablation (RFCA) is a very rare complication, as only two cases have been reported in the English literature. A 42-year-old man underwent RFCA due to recurrent drug-resistant symptomatic atrial fibrillation. The patient complained of indigestion and early satiety 2 days after the procedure. Contrast-enhanced computed tomography and an upper gastrointestinal series of the abdomen showed a large amount of material remaining in the stomach area. All fo

Cardiology and Cardiovascular MedicineMedicine
8
논문|인용수 7·2020
Clinical significance of regional lymph node enlargement in patients with EGC within the expanded criteria for ESD
Dong Seok Lee, Jong Kyu Park, Sang Jin Lee, Gab Jin Cheon
SJR Q2FWCI 0.8BMC GastroenterologyOA

Regional lymph node enlargement on abdominal CT scan in patients within expanded criteria for ESD of ECG may be not due to metastasis but a reactive change.

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 6·2023
Usefulness of a new polyvinyl alcohol hydrogel (PVA-H)-based simulator for endoscopic submucosal dissection training: a pilot study
Dong Seok Lee, Gin Hyug Lee, Sang Gyun Kim, Kook Lae Lee, Ji Won Kim, Ji Bong Jeong, Yong Jin Jung, Hyoun Woo Kang
SJR Q2FWCI 1.6Clinical EndoscopyOA

We have developed a new ESD simulator that can help beginners achieve a high level of technical experience before performing real-time ESD procedures in patients.

Pulmonary and Respiratory MedicineMedicine
10
논문|인용수 5·2019
A Newly Designed 3-Dimensional Printer-Based Gastric Hemostasis Simulator with Two Modules for Endoscopic Trainees (with Video)
Dong Seok Lee, Ji Yong Ahn, Gin Hyug Lee
SJR Q1FWCI 0.3Gut and LiverOA

Background/Aims: We used 3-dimensional (3D) printing technology to create a new hemostasis simulator for the stomach and investigated its efficacy and realism in endoscopic hemostasis training. Methods: A new stomach hemostasis simulator, with two hemostasis modules for hemoclipping and injection, was constructed using a 3D printer. Twenty-one endoscopists, including 11 first-year fellows (beginner group) and 10 faculty members (expert group), tested the performance of the simulator. We recorded

GastroenterologyMedicine
11
논문|인용수 3·2018
Technical Feasibility of a Guidetube for Various Endoscopic Procedures in Human Gastrointestinal Simulators
Dong Seok Lee, Byeong Gwan Kim, Kook Lae Lee, Yong Jin Jung, Ji Won Kim
SJR Q2FWCI 0.5Clinical EndoscopyOA

This preliminary study shows that guidetube-assisted endoscopic procedures are faster, easier, safer and cheaper than conventional endoscopic procedures.

SurgeryMedicine
12
논문|인용수 3·2014
A Case of PICOLIGHT Powder Induced Thermal Injury of the Gastric Mucosa
Dong Seok Lee, Hyeon Seok Kim, Seung Hwan Lee, Joon Ho Jeon, Yong Kyu Lee
FWCI 0.2The Korean Journal of Helicobacter and Upper Gastrointestinal ResearchOA

There are many reports about causes of corrosive agents such as acids and alkaline and occasionally hot food in either liquid or solid forms as causes of upper gastrointestinal mucosal injury. However, there have been no reports on bowel preparation solutions as a cause of upper gastrointestinal injury. We describe a case of bowel preparation solution (PICOLIGHT powder) induced thermal injury of the gastric mucosa with a review of the literature. (

Pulmonary and Respiratory MedicineMedicine
13
논문|인용수 2·2024
Efficacy of colonoscopic re-examination across the entire colon: a randomized controlled trial
Dong Seok Lee, Jeong‐Seon Ji, Tae‐Geun Gweon, Myeongsook Seo, Hwang Choi
SJR Q1FWCI 0.6Surgical Endoscopy
OncologyMedicine
14
논문|인용수 2·2020
Technical feasibility of a newly designed bendable forceps for difficult endoscopic tissue samplings (with video)
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Byeong Gwan Kim, Su Hwan Kim, Jeong‐Sik Byeon
SJR Q1FWCI 0.4Surgical Endoscopy
SurgeryMedicine
15
논문|인용수 2·2020
Analysis of droplets generated during gastrointestinal endoscopic examinations using a high speed camera
Dong Seok Lee, Ji Won Kim
SJR Q1FWCI 0.3EndoscopyOA

Droplets released from the mouth of a COVID-19 infected patient are an important source of infection [1]. Currently, gastrointestinal (GI) endoscopy preventative guidelines have been developed based on cough models with droplet travel distances of over 2 m [2] [3] [4] [5] [6]. However, the droplet-related studies reported so far have mostly focused on cough models related to respiratory disease. Thus far, no studies have been conducted on droplets generated during GI endoscopic examinations.

Pulmonary and Respiratory MedicineMedicine

대표 연구 분야

Pulmonary and Respiratory MedicineSurgeryCardiology and Cardiovascular MedicineOncologyInfectious DiseasesRadiology, Nuclear Medicine and Imaging

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