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김동영 교수

Dong-Young Kim

서울대학교 · 의학

연구실 소개

김동영 교수의 연구실은 생물학적 단백질 품질 제어 메커니즘과 신경망 하드웨어 최적화를 두 축으로 연구를 전개하고 있습니다. 특히 세균의 페리플라즘에서 단백질 분해와 리모델링을 담당하는 HtrA 단백질의 기능적 전환 메커니즘을 구조생물학적 접근으로 규명하고 있으며, 동시에 딥러닝 기반의 초고성능·저에너지 소비 신경망 하드웨어 아키텍처 설계 기술을 개발하고 있습니다. 이는 의료·반도체·IoT 분야의 응용을 겨냥한 실용적 기술 혁신을 목표로 합니다.

HtrA 단백질단백질 품질 제어신경망 하드웨어영구적 최적화에너지 효율 설계

연구 현황

논문 수
327
총 인용 수
4,738
최근 5년 논문
63
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
63총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
189총합
20222023202420252026

주요 논문

15
1
논문|인용수 118·2011
Inverted papilloma of the nasal cavity and paranasal sinuses: A Korean multicenter study
Dong‐Young Kim, Sung‐Lyong Hong, Chul Hee Lee, Hong‐Ryul Jin, Jun Myung Kang, Bong‐Jae Lee, Il Joon Moon, Seung‐Kyu Chung, Ki‐Sang Rha, Seok Hyun Cho, Kyong Rae Kim, Sung Wan Kim
SJR Q1FWCI 1.5The Laryngoscope

Generally, there were no significant differences in recurrence rates according to clinical stage or surgical approach. Given the rate of delayed recurrence, follow-up of >3 years is required. Moreover, surgeons should always consider combined approaches to reduce the chances of recurrence.

SurgeryMedicine
2
논문|인용수 110·2017
ZeNA: Zero-Aware Neural Network Accelerator
Dongyoung Kim, Junwhan Ahn, Sungjoo Yoo
SJR Q3FWCI 4.4IEEE Design and Test

It has been observed that the majority of the kernel weights and input activations in the state-of-the-art convolution neural networks (CNNs) have zero values. This article proposes a CNN hardware accelerator that exploits this property to achieve significant performance and energy improvements.

Computer Vision and Pattern RecognitionComputer Science
3
논문|인용수 63·2017
A novel zero weight/activation-aware hardware architecture of convolutional neural network
Dongyoung Kim, Junwhan Ahn, Sungjoo Yoo
FWCI 3.1

It is imperative to accelerate convolutional neural networks (CNNs) due to their ever-widening application areas from server, mobile to IoT devices. Based on the fact that CNNs can be characterized by a significant amount of zero values in both kernel weights and activations, we propose a novel hardware accelerator for CNNs exploiting zero weights and activations. We also report a zero-induced load imbalance problem, which exists in zero-aware parallel CNN hardware architectures, and present a z

Computer Vision and Pattern RecognitionComputer Science
4
논문|인용수 52·2017
Influencing factors on CPAP adherence and anatomic characteristics of upper airway in OSA subjects
Pona Park, Jin-Il Kim, Yoon Jae Song, Jae Hyun Lim, Sung Woo Cho, Tae‐Bin Won, Doo Hee Han, Dong‐Young Kim, Chae Seo Rhee, Hyun Jik Kim
SJR Q3FWCI 1.7MedicineOA

Although continuous positive airway pressure (CPAP) is the most effective treatment modality, poor adherence still remains a problem for obstructive sleep apnea (OSA) treatment and there is little evidence regarding how this might be improved. This study aims to analyze the anatomic and clinical factors of OSA subjects who failed to comply with CPAP therapy.The medical records of 47 OSA subjects who received CPAP therapy as a first-line treatment modality were retrospectively reviewed. The medic

PhysiologyMedicine
5
리뷰|인용수 48·2015
Chronic Rhinosinusitis and the Coagulation System
Dong‐Young Kim, Seong Cho, Tetsuji Takabayashi, Robert P. Schleimer
SJR Q1FWCI 2.6Allergy Asthma and Immunology ResearchOA

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and severely affects quality of life in patients. Although various etiologic and pathogenic mechanisms of CRS have been proposed, the causes of CRS remain uncertain. Abnormalities in the coagulation cascade may play an etiologic role in many diseases, such as asthma and other inflammatory conditions. While studies on the relationship between asthma and dysregulated coagulation have been reported, the role of the co

OtorhinolaryngologyMedicine
6
논문|인용수 41·2022
Deep Learning Application to Clinical Decision Support System in Sleep Stage Classification
Dong‐Young Kim, Dong‐Young Kim, Jeong‐Gun Lee, Yunhee Woo, Jaemin Jeong, Chulho Kim, Dong‐Kyu Kim, Dong‐Kyu Kim
SJR Q2FWCI 4.7Journal of Personalized MedicineOA

Recently, deep learning for automated sleep stage classification has been introduced with promising results. However, as many challenges impede their routine application, automatic sleep scoring algorithms are not widely used. Typically, polysomnography (PSG) uses multiple channels for higher accuracy; however, the disadvantages include a requirement for a patient to stay one or more nights in the lab wearing uncomfortable sensors and wires. To avoid the inconvenience caused by the multiple chan

PhysiologyMedicine
7
논문|인용수 36·2020
EV-Ident: Identifying Tumor-Specific Extracellular Vesicles by Size Fractionation and Single-Vesicle Analysis
Dongyoung Kim, Hyun‐Kyung Woo, Chaeeun Lee, Yoo Hong Min, Sumit Kumar, Vijaya Sunkara, Hwi-Gyeong Jo, Young Joo Lee, Jisun Kim, Hong Koo Ha, Yoon‐Kyoung Cho
SJR Q1FWCI 1.9Analytical Chemistry

Tumor-derived extracellular vesicles (EVs) have emerged as a promising source of circulating biomarkers for liquid biopsies. However, understanding the heterogeneous physical and biochemical properties of EVs originating from multiple complex biogenesis pathways remains a major challenge. Here, we introduce EV-Ident for preparation of subpopulations of EVs in three different size fractions: large EVs (EV<sub>200 nm</sub>; 200-1 000 nm), medium EVs (EV<sub>100 nm</sub>; 100-200 nm), and small EVs

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 32·2013
Effects of Surgical vs. Nonsurgical Therapy on Erectile Dysfunction and Quality of Life in Obstructive Sleep Apnea Syndrome: A Pilot Study
Hyun‐Woo Shin, Juhyun Park, Jong‐Wan Park, Chae‐Seo Rhee, Chul Hee Lee, Yang-Gi Min, Dong‐Young Kim
SJR Q1FWCI 2.5The Journal of Sexual Medicine

This study demonstrated that ED in OSAS may improve following UPPP. Better disease-specific QOL was observed after both surgical and nonsurgical therapies in OSAS. These findings suggest that interventions for OSAS can provide the alleviation of ED and increase QOL in OSAS patients with ED, especially if they had pronounced complaints of ED and wide neck circumferences.

PhysiologyMedicine
9
논문|인용수 30·2019
AI-powered transmitted light microscopy for functional analysis of live cells
Dongyoung Kim, Yoo Hong Min, Jung Min Oh, Yoon‐Kyoung Cho
SJR Q1FWCI 4.0Scientific ReportsOA

Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of live cells. AIM provides accurate images of subcellular organelles; allows identification of cellular and functional characteristics (cell type, viability, and maturation stage); and facilitates live cell tracking and multimodality analysis of immun

BiophysicsBiochemistry, Genetics and Molecular Biology
10
논문|인용수 29·2020
Del-1, an Endogenous Inhibitor of TGF-β Activation, Attenuates Fibrosis
Dong-Young Kim, Seung Hwan Lee, Yan Fu, Feifeng Jing, Won‐Young Kim, Sang‐Bum Hong, Jung-A Song, Han Choe, Hyun Jin Ryu, Min-Jung Kim, Dahae Lim, Min‐Seon Kim
SJR Q1FWCI 1.9Frontiers in ImmunologyOA

Uncontrolled activation of transforming growth factor (TGF)-β results in a wide range of pathologic conditions. Therapeutic interventions to regulate TGF-β signaling during fibrosis have been developed but the effectiveness is still limited. Here, we show that developmental endothelial locus-1 (Del-1) ameliorates fibrosis in mice by inhibiting α<sub>v</sub> integrin-mediated activation of TGF-β. Del-1 bound to α<sub>v</sub>β<sub>6</sub> integrin, an important activator of TGF-β, and inhibited th

Pulmonary and Respiratory MedicineMedicine
11
논문|인용수 29·2014
Treatment of Allergic Rhinitis Is Associated with Improved Attention Performance in Children: The Allergic Rhinitis Cohort Study for Kids (ARCO-Kids)
Dong‐Kyu Kim, Dong-Kyu Kim, Chae Seo Rhee, Doo Hee Han, Tae‐Bin Won, Dong‐Young Kim, Dong‐Young Kim, Jeong‐Whun Kim
SJR Q1FWCI 2.0PLoS ONEOA

Our study showed that management of allergic rhinitis might be associated with improvement of attention.

Immunology and AllergyMedicine
12
논문|인용수 29·2009
Oral administration of Uncariae rhynchophylla inhibits the development of DNFB-induced atopic dermatitis-like skin lesions via IFN-γ down-regulation in NC/Nga mice
Dong‐Young Kim, Jung‐A Jung, Taeho Kim, Sang-Wan Seo, Sung‐Ki Jung, Cheung‐Seog Park
SJR Q1FWCI 3.5Journal of Ethnopharmacology
DermatologyMedicine
13
논문|인용수 27·2003
Videostrobokymographic Analysis of Benign Vocal Fold Lesions
Dong‐Young Kim, Lee-Suk Kim, Kwang Hyun Kim, Myung‐Whun Sung, Myung‐Whun Sung, Jong-Lyel Roh, Tack‐Kyun Kwon, Sang Joon Lee, Seung‐Ho Choi, Soo-Geun Wang, Mee-Young Sung, Mee-Young Sung
SJR Q2FWCI 0.2Acta Oto-Laryngologica

This study demonstrated that VSK could generate clear quantitative documentation of fine vibrations of vocal folds in many different types of benign lesion. VSK has the potential to be an effective tool for the quantitative analysis of vibratory patterns of vocal folds in clinical settings.

PhysiologyMedicine
14
논문|인용수 24·2007
Primary and secondary fungal infections of the paranasal sinuses: Clinical features and treatment outcomes
Doo Hee Han, Soo-Youn An, Si Whan Kim, Dong‐Young Kim, Chae‐Seo Rhee, Chul Hee Lee, Yang‐Gi Min
SJR Q2FWCI 2.1Acta Oto-Laryngologica

The symptoms of chronic rhinosinusitis such as nasal obstruction, purulent rhinorrhea, and postnasal drip were commonly present in both primary and secondary infections, and the sphenoid sinus was commonly involved in secondary infection. The radiological findings in fungal sinusitis included haziness, calcification, and bone destruction of the involved sinuses. CT scans in 80% of the primary and 69% of the secondary cases revealed calcific densities in a paranasal soft tissue mass. Twenty-eight

OtorhinolaryngologyMedicine
15
논문|인용수 19·2016
Therapeutic outcomes of mandibular advancement devices as an initial treatment modality for obstructive sleep apnea
Pona Park, Hyoung Won Jeon, Doo Hee Han, Tae‐Bin Won, Dong‐Young Kim, Chae‐Seo Rhee, Hyun Jik Kim
SJR Q3FWCI 1.0MedicineOA

Although continuous positive airway pressure (CPAP) is a highly efficacious treatment for obstructive sleep apnea (OSA), there is a need for alternative treatment options, such as sleep surgeries and mandibular advancement devices (MADs), to overcome the limitations of CPAP.This study aimed to analyze the therapeutic outcomes of OSA subjects who were treated with a MAD, and to estimate the clinical impact of MAD as a first-line treatment for OSA.Forty-seven patients diagnosed with OSA received a

PhysiologyMedicine

대표 연구 분야

SurgeryPhysiologyOtorhinolaryngologyImmunology and AllergyMolecular BiologyComputer Vision and Pattern Recognition

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