이기훈 교수
Gihun Lee
서울대학교 · 재료과학
연구실 소개
이기훈 교수의 연구실은 천연 고분자인 실크 세리신, 리그닌, 연어 gelatin 등을 활용한 친환경적이고 비용 효율적인 소재 개발에 주력하고 있습니다. 특히 수중 오염물질 제거를 위한 고성능 흡착재 및 약물 방출 시스템의 설계에서 천연 고분자의 구조 제어와 상호작용 메커니즘을 중심으로 연구를 전개하고 있습니다. 신경 퇴행성 질환과 세포 사멸 메커니즘에 대한 분자 생물학적 연구를 통해 천연 고분자 기반 생체재료의 응용 가능성을 넓히고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15In the present study, novel adsorbents having high adsorption capability and reusability were prepared using agricultural by-products: silk sericin and lignin. Silk sericin and lignin blend beads were successfully prepared using simple coagulation methods for the removal of hexavalent chromium (Cr(VI)) from aqueous solution. A 1 M lithium chloride (LiCl)/dimethyl sulfoxide (DMSO) solvent system successfully dissolved both sericin and lignin and had sufficient viscosity for bead preparation. Comp
Eco-friendly and cost-effective electrospinning of aqueous fish gelatin could prevent the drug crystallization and exhibit the ultra-fast drug release behavior.
Abstract Summary: The thermal and structural analysis of silk fibroin (SF) and silk sericin (SS) blend films reveals that the crystallization of SF is retarded in the presence of SS. Although a phase separation was observed, there might be a strong interaction at the boundary of the SF and SS through intermolecular hydrogen bonding, which restricts the conformational transition of SF. TEM image of the cross‐section of the SF/SS blend (75:25) film (magnification: ×15 000). image TEM image of the
Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by cognitive impairment and memory loss. Amyloid β1-42 (Aβ) and hyper-phosphorylation of microtubule-associated protein tau have been considered as major histological features in AD. However, the mechanism of how Aβ induces the hyper-phosphorylation of tau remains to be clarified. In the present study, we investigated the underlying cellular mechanisms of Aβ with regard to the cell cycle regulatory protein-mediated phosphory
We investigated the topological property of magnon bands in the collinear magnetic orders of zigzag and stripe phases for the antiferromagnetic honeycomb lattice and identified Berry curvature and symmetry constraints on the magnon band structure. Different symmetries of both zigzag and stripe phases lead to different topological properties, in particular, the magnon bands of the stripe phase being disentangled with a finite Dzyaloshinskii-Moriya (DM) term with nonzero spin Chern number. This is
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