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양희범 교수

Hee-Beom Yang

서울대학교 · 의학

연구실 소개

양희범 교수의 연구실은 식물 유전체와 병원균 저항성 유전자 기반의 농업 생물공학을 핵심으로 하며, 고추, 배추, 수박 등 주요 작물의 품질 및 병역성 특성 유전적 기반을 규명하고 있습니다. 특히, QTL 맵핑과 고밀도 유전자 지도를 활용한 품종 개량, 바이러스-숙주 단백질 상호작용을 차단하는 지능형 저항성 기술 개발에 주력하고 있습니다. 또한 신생아 장염증 예방을 위한 생물학적 기전 규명과 수술적 조치 최적화에 관한 의학적 응용 연구도 수행하고 있습니다.

유전자 맵핑병원저항성식물유전체바이러스-숙주 상호작용의료응용

연구 현황

논문 수
86
총 인용 수
871
최근 5년 논문
23
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
23총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
79총합
20222023202420252026

주요 논문

15
1
논문|인용수 128·2016
An ultra-high-density bin map facilitates high-throughput QTL mapping of horticultural traits in pepper (<i>Capsicum annuum</i>)
Koeun Han, Hee-Jin Jeong, Hee‐Bum Yang, Sungmin Kang, Jin‐Kyung Kwon, Seungill Kim, Doil Choi, Byoung‐Cheorl Kang
SJR Q1FWCI 12.3DNA ResearchOA

Most agricultural traits are controlled by quantitative trait loci (QTLs); however, there are few studies on QTL mapping of horticultural traits in pepper (Capsicum spp.) due to the lack of high-density molecular maps and the sequence information. In this study, an ultra-high-density map and 120 recombinant inbred lines (RILs) derived from a cross between C. annuum'Perennial' and C. annuum'Dempsey' were used for QTL mapping of horticultural traits. Parental lines and RILs were resequenced at 18×

GeneticsBiochemistry, Genetics and Molecular Biology
2
논문|인용수 96·2010
Molecular mapping and characterization of a single dominant gene controlling CMV resistance in peppers (Capsicum annuum L.)
Won‐Hee Kang, Ngoc Huy Hoang, Hee‐Bum Yang, Jin‐Kyung Kwon, Sung‐Hwan Jo, Jang‐Kyun Seo, Kook‐Hyung Kim, Doil Choi, Byoung‐Cheorl Kang
SJR Q1FWCI 7.9Theoretical and Applied Genetics
Plant ScienceAgricultural and Biological Sciences
3
논문|인용수 66·2014
Combined use of bulked segregant analysis and microarrays reveals SNP markers pinpointing a major QTL for resistance to Phytophthora capsici in pepper
Wing‐Yee Liu, Jin‐Ho Kang, Hyeon-Seok Jeong, Hye-Jeong Choi, Hee‐Bum Yang, Ki-Taek Kim, Doil Choi, Gyung Ja Choi, Molly Jahn, Byoung‐Cheorl Kang
SJR Q1FWCI 5.6Theoretical and Applied GeneticsOA
Plant ScienceAgricultural and Biological Sciences
4
논문|인용수 48·2014
Transgenic <i> <scp>B</scp> rassica rapa </i> plants over‐expressing <scp>eIF(iso)4E</scp> variants show broad‐spectrum <i>Turnip mosaic virus</i> ( <scp>TuMV</scp> ) resistance
Jin‐Hee Kim, Won‐Hee Kang, JeeNa Hwang, Hee‐Bum Yang, Do‐Sun Kim, Chang‐Sik Oh, Byoung‐Cheorl Kang
SJR Q1FWCI 6.1Molecular Plant PathologyOA

The protein-protein interaction between VPg (viral protein genome-linked) of potyviruses and eIF4E (eukaryotic initiation factor 4E) or eIF(iso)4E of their host plants is a critical step in determining viral virulence. In this study, we evaluated the approach of engineering broad-spectrum resistance in Chinese cabbage (Brassica rapa) to Turnip mosaic virus (TuMV), which is one of the most important potyviruses, by a systematic knowledge-based approach to interrupt the interaction between TuMV VP

Plant ScienceAgricultural and Biological Sciences
5
논문|인용수 39·2016
Rapid and practical molecular marker development for rind traits in watermelon
Sung-woo Park, Ki-Taek Kim, Sun-Cheol Kang, Hee‐Bum Yang
SJR Q1FWCI 1.8Horticulture Environment and Biotechnology
GeneticsBiochemistry, Genetics and Molecular Biology
6
논문|인용수 36·2009
Development of SNP markers linked to the L locus in Capsicum spp. by a comparative genetic analysis
Hee‐Bum Yang, Wing Yee Liu, Won‐Hee Kang, Molly Jahn, Byoung‐Cheorl Kang
SJR Q1FWCI 1.7Molecular Breeding
Plant ScienceAgricultural and Biological Sciences
7
논문|인용수 30·2020
Analysis of Associated Anomalies in Anorectal Malformation: Major and Minor Anomalies
Chaeyoun Oh, Joong Kee Youn, Ji-Won Han, Hee‐Beom Yang, Hyun‐Young Kim, Sung Eun Jung
SJR Q2FWCI 3.3Journal of Korean Medical ScienceOA

A considerable number of patients with ARM had AAs. Our data are useful for predicting AAs in patients with ARM.

SurgeryMedicine
8
논문|인용수 28·2023
Suppressive role of vascular endothelial growth factor on intestinal apoptosis in induced necrotizing enterocolitis in rats
Hee‐Beom Yang, Hyun‐Young Kim, Soo-Hong Kim, S. Kim
SJR Q2FWCI 4.5Annals of Surgical Treatment and ResearchOA

We identified apoptotic and inflammatory genes to confirm the preventive effect of VEGF pretreatment on NEC in rats. This study presents a novel approach to prevent apoptosis via VEGF pretreatment in rats with lipopolysaccharide/hypoxia-induced NEC.

Nutrition and DieteticsNursing
9
논문|인용수 28·2013
Identification of a broad-spectrum recessive gene in Brassica rapa and molecular analysis of the eIF4E gene family to develop molecular markers
Jin‐Hee Kim, Won‐Hee Kang, Hee‐Bum Yang, Suhyoung Park, Chang-Soon Jang, Hee‐Ju Yu, Byoung‐Cheorl Kang
SJR Q1FWCI 1.8Molecular Breeding
Plant ScienceAgricultural and Biological Sciences
10
논문|인용수 26·2015
Linkage Analysis of the Three Loci Determining Rind Color and Stripe Pattern in Watermelon
Hee‐Bum Yang, Sung-woo Park, Young-Hoon Park, Gung Pyo Lee, Sun-Cheol Kang, Yong Kwon Kim
SJR Q3FWCI 1.2Horticultural Science and TechnologyOA

The rind phenotype of watermelon fruits is an important agronomic characteristic in the watermelon market. Inheritance and linkage analyses were performed for three rind-related traits that together determine the rind phenotype: foreground stripe pattern, rind background color, and depth of rind color. The inheritance of the foreground stripe pattern was analyzed using three different <TEX>$F_2$</TEX> populations, showing that the striped pattern is dominant over the non-striped pattern. The inh

GeneticsBiochemistry, Genetics and Molecular Biology
11
논문|인용수 23·2011
Development and validation of L allele-specific markers in Capsicum
Hee‐Bum Yang, Wing-yee Liu, Won‐Hee Kang, Jin‐Hee Kim, Hwa Jin Cho, Jae-hyung Yoo, Byoung‐Cheorl Kang
SJR Q1FWCI 1.6Molecular Breeding
Plant ScienceAgricultural and Biological Sciences
12
논문|인용수 13·2018
The Optimal Timing of Enterostomy Closure in Extremely Low Birth Weight Patients for Acute Abdomen
Hee‐Beom Yang, Ji-Won Han, Joong Kee Youn, Chaeyoun Oh, Hyun-Young Kim, Sung Eun Jung
SJR Q1FWCI 0.6Scientific ReportsOA

Abstract There are few reports on enterostomy closure (EC) timing for acute abdomen in extremely low birth weight (ELBW) patients. We retrospectively reviewed ELBW patients who underwent enterostomy formation (EF) and subsequent EC. We investigated baseline characteristics, surgical outcomes, and follow-up data of 55 patients and analyzed optimal timing by age at EC, enterostomy duration, and body weight (Bwt) at EC. The minimum p-value approach (MPA) using the Chi-squared test was used to deter

Nutrition and DieteticsNursing
13
book chapter|인용수 12·2015
Methods for Developing Molecular Markers
Hee‐Bum Yang, Won‐Hee Kang, Seokhyeon Nahm, Byoung‐Cheorl Kang
FWCI 1.7
Plant ScienceAgricultural and Biological Sciences
14
논문|인용수 9·2019
Pediatric Adenocarcinoma in Korea: A Multicenter Study
Hee‐Beom Yang, Jung‐Man Namgoong, Ki Hoon Kim, Dae Yeon Kim, Jin‐Young Park, Hyun Beak Shin, Joong Kee Youn, Sanghoon Lee, Ji Won Lee, Sung Eun Jung, Jae Hee Chung, Yun-Mee Choe
SJR Q1FWCI 0.4Cancer Research and TreatmentOA

In pediatric patients, adenocarcinomas arise from various organs and are often diagnosed at advanced stages. Large, prospective studies for their accurate clinical characteristics and prognostic factors are needed.

SurgeryMedicine
15
논문|인용수 8·2021
Incidence of necrotizing enterocolitis in South Korea from 2007 to 2017
Hee‐Beom Yang, Jin‐Young Min, Jeik Byun, Dayoung Ko, Hyun‐Young Kim, Kyoung‐Bok Min, Sung Eun Jung
SJR Q1FWCI 0.7Journal of Perinatology
Nutrition and DieteticsNursing

대표 연구 분야

Plant ScienceSurgeryGeneticsNutrition and DieteticsBiomedical EngineeringMolecular Biology

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