정희연 교수
Hee Yeon Jung
서울대학교 · 의학
연구실 소개
정희연 교수의 연구실은 정신질환, 특히 인터넷 게임장애와 병태학적 중독 행동의 신경생물학적 기반을 규명하는 데 초점을 맞추고 있습니다. 뇌 기능과 행동 간의 상관관계를 분석하기 위해 신경생리학적 지표와 행동 평가 도구를 융합한 연구를 지속적으로 수행하고 있으며, 특히 중독성 행동과 정신분열증 환자의 직업재활을 위한 가상현실 기반 치료 프로그램 개발에도 기여하고 있습니다. 신약 개발 및 개인 맞춤형 치료 전략 수립을 위한 생물학적 마커 탐색도 핵심 연구 과제입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Internet addiction has been considered to be associated with poor impulse control. The aim of this study is to compare the trait impulsivity of those suffering from Internet addiction with that of individuals suffering from pathological gambling. Twenty-seven patients diagnosed with Internet addiction (age: 24.78±4.37 years), 27 patients diagnosed with pathological gambling (age: 25.67±3.97 years), and 27 healthy controls (age: 25.33±2.79 years) were enrolled in this study. All patients were men
Alzheimer's disease (AD) is characterized by the deposition of aggregated beta-amyloid (Abeta), which triggers a cellular stress response called the unfolded protein response (UPR). The UPR signaling pathway is a cellular defense system for dealing with the accumulation of misfolded proteins but switches to apoptosis when endoplasmic reticulum (ER) stress is prolonged. ER stress is involved in neurodegenerative diseases including AD, but the molecular mechanisms of ER stress-mediated Abeta neuro
The aim of the present study was to test the impulsivities and compulsivities of behavioral addictions, including Internet gaming disorder (IGD) and gambling disorder (GD), by directly comparing them with alcohol use disorder (AUD) and a healthy control (HC) group. Methods: We enrolled male patients who were diagnosed with IGD, GD or AUD, with 15 patients per group, as well as 15 HCs. Trait impulsivity was measured using the Barratt Impulsiveness Scale version 11 (BIS-11). The stop-signal test (
Abstract The objective of this study was to investigate the feasibility of using an electronic nose (e‐nose) and electronic tongue (e‐tongue) in the sensory profiling of doenjang , a fermented soybean paste. The descriptive analysis of doenjang by trained panelists was compared with that assessed using the e‐nose and e‐tongue. Eighteen aroma/taste/flavor attributes developed by trained panels from 14 doenjang samples were compared with the results from e‐nose and e‐tongue measurements. The e‐nos
Maintaining employment is difficult for patients with schizophrenia because of deterioration of psychosocial and cognitive functions. Such patients usually require vocational rehabilitation training, which is both demanding and costly. In this study, we developed a virtual reality-based vocational rehabilitation training program (VR-VRTP) for such patients and evaluated its feasibility as an alternative to traditional rehabilitation programs. We developed the VR-VRTP to include various situation
The Liverpool University Neuroleptic Side-Effect Rating Scale (LUNSERS) was examined for its usefulness as a subjective measure of drug-induced parkinsonism and akathisia. Eighty-three subjects were assessed using the LUNSERS, the Simpson-Angus Scale (SAS) and the Barnes Akathisia Rating Scale (BARS), before and after a 6-week treatment with olanzapine. Significant correlations were found between the changes in scores of parkinsonism items of LUNSERS and SAS. The changes in scores of akathisia i
The authors conducted a survey on essential humanistic competency that medical students should have, and on teaching methods that will effectively develop such attributes. The participants consisted of 154 medical school professors, 589 medical students at Seoul National University College of Medicine, 228 parents, and 161 medical school and university hospital staff. They answered nine questions that the authors created. According to the results, all groups chose “morality and a sense of ethics
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