김호중 교수
Ho Joong Kim
서울대학교 · 의학
연구실 소개
김호중 교수의 연구실은 주로 생체재료 및 나노소재를 활용한 의료 응용 분야에 집중하고 있습니다. 특히 수용성 고분자와 펩타이드를 조합한 자가조립 나노구조를 통해 조직 재생, 지속적 약물 방출, 눈 질환 치료 등에 활용 가능한 생체적합성 있는 신소재를 개발하고 있습니다. 로봇 보조 척추 외과 수술의 품질 모니터링 및 약물 전달 시스템의 정밀 제어 기술 개발을 통해 임상 응용 가능성을 높이고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15During the past decade, supramolecular nanostructures produced via self-assembly processes have received considerable attention because these structures can lead to dynamic materials. Among these diverse self-assembly systems, the aqueous assemblies that result from the sophisticated design of molecular building blocks offer many potential applications for producing biocompatible materials that can be used for tissue regeneration, drug delivery, and ion channel regulation. Along this line, resea
Robotic-assisted pedicle screw placement was associated with fewer proximal facet joint violations and better convergence orientations.
Temporarily implanted devices, such as drug-loaded contact lenses, are emerging as the preferred treatment method for ocular diseases like glaucoma. Localizing the delivery of glaucoma drugs, such as timolol maleate (TM), can minimize adverse effects caused by systemic administration. Although eye drops and drug-soaked lenses allow for local treatment, their utility is limited by burst release and a lack of sustained therapeutic delivery. Additionally, wet transportation and storage of drug-soak
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
First, this study demonstrates the adequacy of quality control of robot-assisted pedicle screw fixation even early in the application period based on the CUSUM analysis. Second, the CUSUM test can be a useful tool for monitoring of the quality of procedures related with spine surgery.
The purpose of this study was to investigate the anti-inflammatory effect of platelet-rich plasma (PRP) with collagen matrix on human nucleus pulposus (NP) cell in response to pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-1 (IL-1). NP cells from human disks were cultured in a monolayer and maintained in the collagen matrix prior to the addition of recombinant human IL-1 and TNF-α. After applying IL-1 and TNF-α, PRP prepared by using a commercially availab
In models of 1-segment lumbar fusion surgery, the positions of pedicle screws were closely linked with corresponding disc stresses and facet contact forces. However, even in cases of facet violation by pedicle screws, removal of the pedicle screw after fusion completion can reduce facet contract forces and disc stresses under both extension and torsional moments.
The current study highlights that patients with symptomatic LSS have a risk of a fall comparable with the patients who had degenerative KOA based on the results of functional mobility tests (SMT, STS, AST, and TUGT).
3.
A poor surgical outcome would be inevitable because of the worsening of symptoms owing to the natural history of PD. Therefore, our current study suggested surgical indication should be exercised cautiously in the patients with PD and spinal stenosis.
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