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정호경 교수

Hokyung Choung

서울대학교 · 의학

연구실 소개

정호경 교수의 연구실은 주로 눈 주변 부위의 희귀 질환, 특히 IgG4 관련 질환과 눈부속성 림프종의 발병 기전과 치료 전략을 중심으로 연구를 진행하고 있습니다. 특히 IgG4-ROD에서의 병변 진행 위험 요인 분석, MALT 림프종의 유전자 메틸화 변화와 병원체 연관성, 그리고 어린이 망막모세포종 환자에서의 인공눈물 임플란트 수술 기법 개선 등 임상적 실용성과 기초 기전 연구를 융합한 연구가 특징입니다. 최근에는 신호전달 경로의 활성화가 악성 종양의 침습성과 전이에 미치는 영향에 대해서도 깊이 있는 분석을 수행하고 있습니다.

IgG4 관련 질환눈부속성 림프종메틸화임플란트 수술신호전달 경로

연구 현황

논문 수
167
총 인용 수
1,563
최근 5년 논문
25
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
25총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
159총합
20212022202320242025

주요 논문

15
1
논문|인용수 39·2017
Risk factors for extraophthalmic involvement and treatment outcomes in patients with IgG4-related ophthalmic disease
Jinku Park, Min Joung Lee, Namju Kim, Ji Eun Kim, Sun‐Won Park, Ho-Kyung Choung, Sang In Khwarg
SJR Q1FWCI 3.5British Journal of Ophthalmology

Bilateral involvement, longer symptom duration and higher IgG4 levels were significant risk factors for extraophthalmic involvement in Korean patients with IgG4-ROD. In patients with an extraophthalmic involvement, prednisolone combined with an immunosuppressive agent was more effective for preventing recurrence than prednisolone alone.

RheumatologyMedicine
2
논문|인용수 21·2013
Outcome of smooth surface tunnel porous polyethylene orbital implants (Medpor SST) in children with retinoblastoma
Youn Joo Choi, Chaerin Park, Hyun Chul Jin, Ho-Kyung Choung, Min Joung Lee, Namju Kim, Sang In Khwarg, Young Suk Yu
SJR Q1FWCI 1.6British Journal of Ophthalmology

Medpor SST is relatively safe, allowing for a mean follow-up of 5 years in terms of implant exposure, and may be a good choice of orbital implant for children with retinoblastoma.

GeneticsBiochemistry, Genetics and Molecular Biology
3
논문|인용수 21·2012
Multigene Methylation Analysis of Ocular Adnexal MALT Lymphoma and Their Relationship to<i>Chlamydophila psittaci</i>Infection and Clinical Characteristics in South Korea
Ho-Kyung Choung, Young A Kim, Min Joung Lee, Namju Kim, Sang In Khwarg
SJR Q1FWCI 1.2Investigative Ophthalmology & Visual Science

Aberrant CpG island methylation of tumor suppressor genes is a frequent event in ocular adnexal MALT lymphoma. In particular, high frequencies of DAPK and ECAD methylation may be strongly correlated with ocular adnexal MALT lymphomagenesis in South Korea. Furthermore, ECAD hypermethylation is closely associated with C. psittaci infection, which may shed light on the mechanisms of bacterium-induced oncogenesis.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
논문|인용수 20·2012
Expression of Shh and Wnt Signaling Pathway Proteins in Eyelid Sebaceous Gland Carcinoma: Clinicopathologic Study
Namju Kim, Ji Eun Kim, Ho-Kyung Choung, Min Joung Lee, Sang In Khwarg
SJR Q1FWCI 0.5Investigative Ophthalmology & Visual ScienceOA

The group with metastasis showed higher expression levels of Shh, ABCG2, and Wnt than did the group without metastasis, and patients with strong ABCG2 expression, Wnt, or LRP expression showed higher cumulative incidence of lymph node or distant metastasis, implying that activation of the Shh and Wnt signaling pathway is associated with aggressive behavior of the tumor.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
논문|인용수 17·2015
Clinicopathological Analysis of Ocular Adnexal Extranodal Marginal Zone B-Cell Lymphoma with IgG4-Positive Cells
Min Joung Lee, Namju Kim, Ji‐Young Choe, Sang In Khwarg, Yoon Kyung Jeon, Ho-Kyung Choung, Ji Eun Kim
SJR Q1FWCI 1.3PLoS ONEOA

This study aims to analyze clinical and pathologicalcharacteristics of ocular adnexal extranodal marginal zone B-celllymphoma (EMZL) accompanying IgG4-positive cells. Fifty patients with a diagnosis of primary non-conjunctival ocular adnexal EMZL were enrolled in this study. The number of IgG4-positive cells and the ratio of IgG/IgG4 were evaluated by immunohistochemistry in the biopsy specimens. The patients were divided into two groups based on the absolute number and the ratio of IgG4-positiv

RheumatologyMedicine
6
논문|인용수 15·2005
Retroscleral Implantation Technique for Porous Polyethylene Orbital Implant After Evisceration
Ho-Kyung Choung, Soo Kyung Han, Sang In Khwarg
SJR Q2FWCI 0.6Ophthalmic surgery, lasers & imaging retina

The authors developed a technique for the retroscleral implantation of a porous polyethylene orbital implant after evisceration for the placement of an adequately large orbital implant without wound tension. The surgical results of the technique in 27 patients are reported. The technique involves the severance of the optic nerve after standard evisceration and the insertion of the orbital implant into the retroscleral and intraconal space through the side of the scleral shell. All patients recei

GeneticsBiochemistry, Genetics and Molecular Biology
7
논문|인용수 15·2014
Squinting and Photophobia in Intermittent Exotropia
Baek‐Lok Oh, Soh-Youn Suh, Ho-Kyung Choung, Seong-Joon Kim
SJR Q2FWCI 0.6Optometry and Vision Science

More than 50% of patients with intermittent exotropia had squinting or photophobia, and approximately 60% of symptomatic patients experienced improvement postoperatively. The onset of strabismus, near fusion, superior oblique overaction, and fundus intorsion were related to these symptoms. Early surgery and successful eye position realignment were beneficial for improving squinting postoperatively.

Pathology and Forensic MedicineMedicine
8
논문|인용수 13·2018
Case Series: Herpes Zoster Ophthalmicus with Acute Orbital Inflammation
Eunoo Bak, Namju Kim, Sang In Khwarg, Ho-Kyung Choung
SJR Q2FWCI 0.8Optometry and Vision Science

Herpes zoster ophthalmicus may initially present with orbital inflammatory signs, such as acute orbital myositis, perioptic neuritis, or dacryoadenitis, without zoster rash. Physicians should be aware of acute orbital inflammation as a presenting sign of HZO.

EpidemiologyMedicine
9
논문|인용수 11·2008
Slow-Releasing Paclitaxel in Polytetrafluoroethylene/Polylactide-co-glycolide Laminate Delays Adjustment after Strabismus Surgery in Rabbit Model
Ho-Kyung Choung, Su-Eon Jin, Min Joung Lee, Chong-Kook Kim, Jeong‐Min Hwang
SJR Q1FWCI 0.6Investigative Ophthalmology & Visual Science

Slow-releasing paclitaxel in PTFE/PLGA was found to reduce adhesion and allowed delayed adjustment in most eyes for up to 5 weeks after surgery.

Pathology and Forensic MedicineMedicine
10
논문|인용수 8·2005
The Use of Surgi Wrap in Delayed Adjustable Strabismus Surgery
Ho-Kyung Choung, Jeong‐Min Hwang
SJR Q1FWCI 0.4American Journal of Ophthalmology
Pathology and Forensic MedicineMedicine
11
논문|인용수 7·2015
Clinicopathologic Study of Chromosomal Aberrations in Ocular Adnexal Lymphomas of Korean Patients
Ho-Kyung Choung, Young A Kim, Namju Kim, Min Joung Lee, Sang In Khwarg
SJR Q2FWCI 0.7Korean Journal of OphthalmologyOA

Translocations involving the MALT1 gene are not common in Korean ocular adnexal MALT lymphomas. The t(14;18) translocation was detected in only one out of 30 cases, and the t(11;18) translocation was not found at all. Furthermore, the chromosomal aberrations found in this study had no prognostic implications.

Pathology and Forensic MedicineMedicine
12
논문|인용수 6·2021
Central retinal vascular trunk deviation in unilateral normal-tension glaucoma
Ho-Kyung Choung, Martha Kim, Sohee Oh, Kyoung Min Lee, Seok Hwan Kim
SJR Q1FWCI 0.9PLoS ONEOA

The offset index was larger in the unilateral NTG eyes, which fact is suggestive of the potential role of LC/BMO offset as a loco-regional susceptibility factor.

OphthalmologyMedicine
13
논문|인용수 5·2019
A conjunctival-sparing surgical technique for lower eyelid cicatricial entropion repair in ocular cicatricial pemphigoid
Ho-Kyung Choung, Edith R. Reshef, Thidarat Tanking, Suzanne K. Freitag
SJR Q3FWCI 0.3Orbit

<b>Purpose</b>: To present five cases of lower eyelid cicatricial entropion secondary to ocular cicatricial pemphigoid (OCP) successfully repaired with a conjunctival-sparing surgical technique.<b>Methods</b>: The records of one surgeon (SKF) were reviewed to identify patients with lower eyelid cicatricial entropion secondary to OCP who underwent repair with a conjunctival-sparing technique between September 1, 2016 and October 18, 2017. The medical records were reviewed and extracted data inclu

Pathology and Forensic MedicineMedicine
14
논문|인용수 5·2022
Ophthalmic manifestations and visual outcomes of granulomatosis with polyangiitis: a retrospective multicentre study in Korea
Min Kyu Yang, Hye Won Kim, Eun Ha Kang, Namju Kim, Ho-Kyung Choung, Sang In Khwarg
SJR Q1FWCI 0.6EyeOA
Pulmonary and Respiratory MedicineMedicine
15
논문|인용수 4·2017
Epiblepharon in congenital glaucoma: case–control study
Namju Kim, Yung Ju Yoo, Ho-Kyung Choung, Sang In Khwarg
SJR Q1FWCI 0.2British Journal of Ophthalmology

The prevalence of epiblepharon was higher in patients with congenital glaucoma compared with age-matched general population. In patients with congenital glaucoma, epiblepharon was associated with corneal erosions. In addition, buphthalmos and initial high IOP were associated with the development of lower lid epiblepharon. More importantly, unilateral buphthalmos was also significantly associated with unilateral epiblepharon. Therefore, in patients with congenital glaucoma, presence of epiblephar

OphthalmologyMedicine

대표 연구 분야

OphthalmologyPathology and Forensic MedicineDermatologyEpidemiologyGeneticsRheumatology

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