이화진 교수
Hwajin Lee
서울대학교 · 공학
연구실 소개
이화진 교수의 연구실은 노화 및 만성질환에 대응하는 비약리적 치료법 개발과 신체기능 회복을 중심으로 한 예방적 건강관리 전략을 연구합니다. 특히 퇴행성 관절염 환자의 삶의 질 향상과 뇌-신경-호르몬 조절을 통한 스트레스 반응 조절, 자가세포 치료를 위한 세포 전환 기술 개발에 초점을 맞추고 있습니다. 또한 환경행동 이론을 기반으로 한 환경교육 및 건강 행동 변화 연구를 통해 예방의학의 이론적 기반을 다지고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Tai Chi Qigong training appears to have beneficial effects in terms of the quality of life and physical functioning of elderly subjects with knee osteoarthritis. However, more rigorous trials are needed to confirm the efficacy of this training for patients with osteoarthritis of the knee.
We have identified three differentially methylated regions associated with gestational age at birth. All three nearby genes play important roles in the development of several organs, including skeletal muscle, brain and haematopoietic system. Therefore, they may provide initial insight into the basis of PTB's negative health outcomes. The genome-wide custom DNA methylation array technology and novel statistical methods employed in this study could constitute a model for epidemiologic studies of
본 연구는 환경행동과 관련된 여러 연구들 중에서도 계획된 행동이론, 규범 활성화 모형, 가치-신념-규범 이론을 바탕으로 한 국내 연구 현황을 분석하고, 이를 바탕으로 향후 환경교육에서 나아가야 할 연구 방향에 대해 제시하고자 하였다. 이를 위해 2011년∼2020년까지 국내의 여러 학술지에 게재된 환경행동이론을 활용한 26개 논문들에 대해 연구대상, 연구방법, 활용이론, 환경행동 결정요인을 준거로 하여 분석하였다. 분석 결과, 최근 10년간 환경행동이론을 바탕으로 한 연구가 활발히 진행 중이지만, 대다수는 특정한 성인을 대상으로 이뤄져왔고 계획된 행동이론에 집중된 경향이 있다. 따라서, 향후 환경교육 분야에서 학생을 포함한 불특정 다수의 많은 사람들을 대상으로 할 필요성이 있고, 환경행동을 보다 잘 설명하기 위해 여러 이론들을 융합하여 연구할 필요성이 있다. 또한, 환경행동이 어떤 것인가에 따라 결정요인의 영향력의 정도가 달라지는지를 다양한 연구방법을 통해 알아볼 필요가 있겠다.
Limitation in cell sources for autologous cell therapy has been a recent focus in stem cell therapy and tissue engineering. Among various research advances, direct conversion, or transdifferentiation, is a notable and feasible strategy for the generation and acquirement of wanted cell source. So far, utilizing cell transdifferentiation technology in tissue engineering was mainly restricted at achieving single wanted cell type from diverse cell types with high efficiency. However, regeneration of
Adjustment of Middle-aged People with Hemiplegia after a Stroke Lee, Hwa Jin1)․Yi, Myungsun2) 1) Doctoral Candidate, Graduate School of Seoul National University; Researcher at the College of Nursing, Seoul National University 2) Professor at the College of Nursing, Seoul National University; Researcher, The Research Institute of Nursing Science, Seoul National University Purpose: The purpose of this study was to understand the adjustment process of middle-aged people in Korea with hemiple
Vagal withdrawal and sympathetic overactivity accompany various types of stress. Qi training is reported to reduce sympathetic hyper-reactivity in a stressful situation. Turo, which is a type of dance that uses the Meridian Qi System, may reduce the psychological symptoms induced by an imbalance of the autonomic nervous system (ANS). We observed whether Turo training alters psychopathological and psychological symptoms using the Symptom Checklist 90-Revision (SCL-90-R) and examined whether it at
Herein, the effects of various alcohols on lecithin/CaCl<sub>2</sub> organogels are investigated. Mixtures of lecithin and CaCl<sub>2</sub> form reverse cylindrical micelles, resulting in optically transparent organogels. The addition of various alcohols to a mixture of lecithin and CaCl<sub>2</sub> induces a decrease in viscosity through which reverse cylindrical micelles are transformed into spherical micelles (or short cylindrical micelles). Long-hydrocarbon-chain alcohols decrease the viscos
We present here COOBoostR, a computational method designed for the putative prediction of the tissue- or cell-of-origin of various cancer types. COOBoostR leverages regional somatic mutation density information and chromatin mark features to be applied to an extreme gradient boosting-based machine-learning algorithm. COOBoostR ranks chromatin marks from various tissue and cell types, which best explain the somatic mutation density landscape of any sample of interest. A specific tissue or cell ty
Acquiring adequate number of cells is one of the crucial factors to apply tissue engineering strategies in order to recover critical-sized defects. While the reprogramming technology used for inducing pluripotent stem cells (iPSCs) opened up a direct path for generating pluripotent stem cells, a direct conversion strategy may provide another possibility to obtain desired cells for tissue engineering. In order to convert a somatic cell into any other cell type, diverse approaches have been invest
This study was carried out to analyze the home ranges of three medium-sized mammals(Nyctereutes procyonoides, Prionailurus bengalensis, and Meles leucurus) inhabiting the Sobaeksan National Park, Korea. Three individuals of each species were captured using live traps(Tomahawk live trap 210A) and radio tracking was conducted from June 2012 to May 2014 using VHF and CDMA methods. We determined that the home range of N. procyonoides was <TEX>$6.53{\pm}6.66km^2$</TEX>(MCP 100), <TEX>$3.39{\pm}4.73km
The older adult population is rapidly increasing in South Korea, and hospitalization at general hospitals is increasing too. Therefore, nurses working at general hospitals need the nursing competency for older adult patients. The study was conducted to examine the effects of nurses' perception of the older adults and work stress on the nursing competency of nurses at a general hospital, South Korea. A cross-sectional, descriptive correlational design was employed. Participants were a total of 13
This study examined the relationship between family support and symptom of depressive among married working women, using the dataset of the Korean Longitudinal Survey of Women & Family (KLoWF 4th). There were 1,875 subjects. A multiple regression model was used to study the association between family support and symptom of depressive, controlling for economic-socio characteristics, health status and health behavior. Additionally, this study ran three subgroup regression models based on hierarchi
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