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이화진 교수

Hwajin Lee

서울대학교 · 공학

연구실 소개

이화진 교수의 연구실은 노화 및 만성질환에 대응하는 비약리적 치료법 개발과 신체기능 회복을 중심으로 한 예방적 건강관리 전략을 연구합니다. 특히 퇴행성 관절염 환자의 삶의 질 향상과 뇌-신경-호르몬 조절을 통한 스트레스 반응 조절, 자가세포 치료를 위한 세포 전환 기술 개발에 초점을 맞추고 있습니다. 또한 환경행동 이론을 기반으로 한 환경교육 및 건강 행동 변화 연구를 통해 예방의학의 이론적 기반을 다지고 있습니다.

퇴행성 관절염자율신경 조절세포 전환심리적 스트레스 반응환경행동 이론

연구 현황

논문 수
413
총 인용 수
2,748
최근 5년 논문
40
주요 분야
공학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
40총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
99총합
20212022202320242025

주요 논문

15
1
논문|인용수 153·2009
Tai Chi Qigong for the quality of life of patients with knee osteoarthritis: a pilot, randomized, waiting list controlled trial
Hwa-Jin Lee, Hwa-Jin Lee, Hi‐Joon Park, Younbyoung Chae, Song‐Yi Kim, Seung‐Nam Kim, Seung-Tae Kim, Je-Ho Kim, Chang-Shik Yin, Hyejung Lee, Hyejung Lee
SJR Q1FWCI 6.2Clinical Rehabilitation

Tai Chi Qigong training appears to have beneficial effects in terms of the quality of life and physical functioning of elderly subjects with knee osteoarthritis. However, more rigorous trials are needed to confirm the efficacy of this training for patients with osteoarthritis of the knee.

PharmacologyMedicine
2
논문|인용수 75·2012
DNA methylation shows genome-wide association of<i>NFIX</i>,<i>RAPGEF2</i>and<i>MSRB3</i>with gestational age at birth
Hwa-Jin Lee, Andrew E. Jaffe, Jason I. Feinberg, Rakel Tryggvadóttir, Shannon Brown, Carolina Montaño, Martin J. Aryee, Rafael A. Irizarry, Julie B. Herbstman, Frank R. Witter, Lynn R. Goldman, Andrew P. Feinberg
SJR Q1FWCI 12.8International Journal of EpidemiologyOA

We have identified three differentially methylated regions associated with gestational age at birth. All three nearby genes play important roles in the development of several organs, including skeletal muscle, brain and haematopoietic system. Therefore, they may provide initial insight into the basis of PTB's negative health outcomes. The genome-wide custom DNA methylation array technology and novel statistical methods employed in this study could constitute a model for epidemiologic studies of

Pediatrics, Perinatology and Child HealthMedicine
3
논문|인용수 36·2021
환경행동이론(TPB, NAM, VBN)에 기반한 환경행동에 대한 국내 연구 동향
이화진
환경교육

본 연구는 환경행동과 관련된 여러 연구들 중에서도 계획된 행동이론, 규범 활성화 모형, 가치-신념-규범 이론을 바탕으로 한 국내 연구 현황을 분석하고, 이를 바탕으로 향후 환경교육에서 나아가야 할 연구 방향에 대해 제시하고자 하였다. 이를 위해 2011년∼2020년까지 국내의 여러 학술지에 게재된 환경행동이론을 활용한 26개 논문들에 대해 연구대상, 연구방법, 활용이론, 환경행동 결정요인을 준거로 하여 분석하였다. 분석 결과, 최근 10년간 환경행동이론을 바탕으로 한 연구가 활발히 진행 중이지만, 대다수는 특정한 성인을 대상으로 이뤄져왔고 계획된 행동이론에 집중된 경향이 있다. 따라서, 향후 환경교육 분야에서 학생을 포함한 불특정 다수의 많은 사람들을 대상으로 할 필요성이 있고, 환경행동을 보다 잘 설명하기 위해 여러 이론들을 융합하여 연구할 필요성이 있다. 또한, 환경행동이 어떤 것인가에 따라 결정요인의 영향력의 정도가 달라지는지를 다양한 연구방법을 통해 알아볼 필요가 있겠다.

4
논문|인용수 30·2020
Ectopic transient overexpression of <i>OCT-4</i> facilitates BMP4-induced osteogenic transdifferentiation of human umbilical vein endothelial cells
Seung Hyun L. Kim, Seunghun S. Lee, Inseon Kim, Janet Kwon, S. Chul Kwon, Taegeun Bae, Junho K. Hur, Hwa-Jin Lee, Nathaniel S. Hwang
SJR Q1FWCI 2.0Journal of Tissue EngineeringOA

Limitation in cell sources for autologous cell therapy has been a recent focus in stem cell therapy and tissue engineering. Among various research advances, direct conversion, or transdifferentiation, is a notable and feasible strategy for the generation and acquirement of wanted cell source. So far, utilizing cell transdifferentiation technology in tissue engineering was mainly restricted at achieving single wanted cell type from diverse cell types with high efficiency. However, regeneration of

Biomedical EngineeringEngineering
5
논문|인용수 25·2010
Acupuncture attenuates autonomic responses to smoking-related visual cues
Younbyoung Chae, Hi‐Joon Park, O-Seok Kang, Hwa-Jin Lee, Hwa-Jin Lee, Song‐Yi Kim, Chang-Shik Yin, Hyejung Lee, Hyejung Lee
SJR Q1FWCI 2.7Complementary Therapies in Medicine
Complementary and alternative medicineMedicine
6
논문|인용수 19·2017
Nonlinear piezoelectric dual sensor for the detection of angle and radius of a bending deformation
Hwa-Jin Lee, Sung Yun Chung, Youn Sang Kim, Tae Il Lee
SJR Q1FWCI 1.0Nano Energy
Biomedical EngineeringEngineering
7
논문|인용수 19·2006
뇌졸중 후 편마비를 가진 중년기 환자의 적응과정
이화진, 이명선

Adjustment of Middle-aged People with Hemiplegia after a Stroke Lee, Hwa Jin1)․Yi, Myungsun2) 1) Doctoral Candidate, Graduate School of Seoul National University; Researcher at the College of Nursing, Seoul National University 2) Professor at the College of Nursing, Seoul National University; Researcher, The Research Institute of Nursing Science, Seoul National University Purpose: The purpose of this study was to understand the adjustment process of middle-aged people in Korea with hemiple

8
논문|인용수 14·2007
Turo (Qi Dance) Training Attenuates Psychological Symptoms and Sympathetic Activation Induced by Mental Stress in Healthy Women
Hwa-Jin Lee, Younbyoung Chae, Hi‐Joon Park, Dae‐Hyun Hahm, Kyungeh An, Hyejung Lee
FWCI 0.4Evidence-based Complementary and Alternative MedicineOA

Vagal withdrawal and sympathetic overactivity accompany various types of stress. Qi training is reported to reduce sympathetic hyper-reactivity in a stressful situation. Turo, which is a type of dance that uses the Meridian Qi System, may reduce the psychological symptoms induced by an imbalance of the autonomic nervous system (ANS). We observed whether Turo training alters psychopathological and psychological symptoms using the Symptom Checklist 90-Revision (SCL-90-R) and examined whether it at

Cardiology and Cardiovascular MedicineMedicine
9
논문|인용수 13·2020
Mechanism for Transition of Reverse Cylindrical Micelles to Spherical Micelles Induced by Diverse Alcohols
Hwa-Jin Lee, Hwa-Jin Lee, Hyun‐Jin Kim, Da-Gyun Park, Kyeong Sik Jin, Ji Woong Chang, Hee-Young Lee, Hee-Young Lee
SJR Q1FWCI 0.9Langmuir

Herein, the effects of various alcohols on lecithin/CaCl<sub>2</sub> organogels are investigated. Mixtures of lecithin and CaCl<sub>2</sub> form reverse cylindrical micelles, resulting in optically transparent organogels. The addition of various alcohols to a mixture of lecithin and CaCl<sub>2</sub> induces a decrease in viscosity through which reverse cylindrical micelles are transformed into spherical micelles (or short cylindrical micelles). Long-hydrocarbon-chain alcohols decrease the viscos

Organic ChemistryChemistry
10
논문|인용수 8·2022
COOBoostR: An Extreme Gradient Boosting-Based Tool for Robust Tissue or Cell-of-Origin Prediction of Tumors
Sungmin Yang, Kyungsik Ha, Woojeung Song, Masashi Fujita, Kirsten Kübler, Paz Polak, Eiso Hiyama, Hidewaki Nakagawa, Hong‐Gee Kim, Hwa-Jin Lee
SJR Q1FWCI 0.8LifeOA

We present here COOBoostR, a computational method designed for the putative prediction of the tissue- or cell-of-origin of various cancer types. COOBoostR leverages regional somatic mutation density information and chromatin mark features to be applied to an extreme gradient boosting-based machine-learning algorithm. COOBoostR ranks chromatin marks from various tissue and cell types, which best explain the somatic mutation density landscape of any sample of interest. A specific tissue or cell ty

Cancer ResearchBiochemistry, Genetics and Molecular Biology
11
리뷰|인용수 7·2016
Non‐viral approaches for direct conversion into mesenchymal cell types: Potential application in tissue engineering
Eun‐Seo Lee, Seung Hyun L. Kim, Hwa-Jin Lee, Nathaniel S. Hwang
SJR Q2FWCI 0.9Journal of Biomedical Materials Research Part B Applied Biomaterials

Acquiring adequate number of cells is one of the crucial factors to apply tissue engineering strategies in order to recover critical-sized defects. While the reprogramming technology used for inducing pluripotent stem cells (iPSCs) opened up a direct path for generating pluripotent stem cells, a direct conversion strategy may provide another possibility to obtain desired cells for tissue engineering. In order to convert a somatic cell into any other cell type, diverse approaches have been invest

Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
논문|인용수 7·2014
Home Range Analysis of Three Midium-Sized Mammals in Sobaeksan National Park
Hwa-Jin Lee, Jin-Yeol Cha, Chul‐Un Chung, Young‐Chae Kim, Sung‐Chul Kim, Gu-Hee Kwon, Jung-Jin Kim
Journal of the Korea Society of Environmental Restoration TechnologyOA

This study was carried out to analyze the home ranges of three medium-sized mammals(Nyctereutes procyonoides, Prionailurus bengalensis, and Meles leucurus) inhabiting the Sobaeksan National Park, Korea. Three individuals of each species were captured using live traps(Tomahawk live trap 210A) and radio tracking was conducted from June 2012 to May 2014 using VHF and CDMA methods. We determined that the home range of N. procyonoides was <TEX>$6.53{\pm}6.66km^2$</TEX>(MCP 100), <TEX>$3.39{\pm}4.73km

EcologyEnvironmental Science
13
논문|인용수 7·2023
The Effects of Nurses’ Perception of the Older Adults and Work Stress on Nursing Competency of Nurses Who Care for Older Adult Patients at General Hospital
Hwa-Jin Lee, Minkyung Gu, Sohyune Sok
SJR Q2FWCI 2.2International Journal of Environmental Research and Public HealthOA

The older adult population is rapidly increasing in South Korea, and hospitalization at general hospitals is increasing too. Therefore, nurses working at general hospitals need the nursing competency for older adult patients. The study was conducted to examine the effects of nurses' perception of the older adults and work stress on the nursing competency of nurses at a general hospital, South Korea. A cross-sectional, descriptive correlational design was employed. Participants were a total of 13

Clinical PsychologyPsychology
14
논문|인용수 6·1997
Antioxidant Components from Broussonetia kazinoki
이화진, 박재현, 장동일, 류재하
YAKHAK HOEJI
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
논문|인용수 5·2015
Effects of Family Support on Depression among Married Working Women
Hwajin Lee, Eun‐Kyoung Seo, Yu-Rim Jeong, Nam In-Suk, Sam-Sung Han
FWCI 1.2The Korean Journal of Health Service Management

This study examined the relationship between family support and symptom of depressive among married working women, using the dataset of the Korean Longitudinal Survey of Women & Family (KLoWF 4th). There were 1,875 subjects. A multiple regression model was used to study the association between family support and symptom of depressive, controlling for economic-socio characteristics, health status and health behavior. Additionally, this study ran three subgroup regression models based on hierarchi

General Health ProfessionsHealth Professions

대표 연구 분야

Aerospace EngineeringSociology and Political ScienceInformation SystemsMolecular BiologyPublic Health, Environmental and Occupational HealthPharmacology

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