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제환준 교수

Hwan Jun Jae

서울대학교 · 의학

연구실 소개

제환준 교수의 연구실은 혈관내 치료 기반의 비정상성 상처 및 종양 치료를 핵심으로 삼고 있습니다. 특히 비정맥성 위장관 출혈에서의 경색술(embolization) 기법, 나노입자 기반 약물 전달 시스템, 그리고 종양 치료 후 반응 평가를 위한 체질적 영상 진단 기술 개발에 주력하고 있습니다. 특히 N-부틸 사이아노아크릴레이트(NBCA)를 활용한 혈관 타겟팅 치료와 퍼피usion CT를 통한 조기 재발 탐지 기술은 임상적 응용가치가 매우 높습니다.

경색술혈관 치료종양 치료영상 진단약물 전달

연구 현황

논문 수
219
총 인용 수
5,078
최근 5년 논문
17
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
17총합
2021
2022
2024
2025
2026
5개년 연도별 피인용 수
113총합
20212022202420252026

주요 논문

15
1
논문|인용수 108·2007
Transcatheter Arterial Embolization of Nonvariceal Upper Gastrointestinal Bleeding with N-Butyl Cyanoacrylate
Hwan Jun Jae, Jin Wook Chung, Ah Young Jung, Whal Lee, Jae Hyung Park
SJR Q1FWCI 3.0Korean Journal of RadiologyOA

TAE with NBCA is a highly effective and safe treatment modality for nonvariceal upper gastrointestinal bleeding, especially when it is not possible to advance the microcatheter to the bleeding site and when the patient has a coagulopathy.

GastroenterologyMedicine
2
논문|인용수 58·2007
Transcatheter Arterial Embolization of Nonvariceal Upper Gastrointestinal Bleeding with N-Butyl Cyanoacrylate
제환준, 정진욱, 정아영, 이활, 박재형

Objective: To evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with N-Butyl Cyanoacrylate (NBCA) for nonvariceal upper gastrointestinal bleeding. Materials and Methods: Between March 1999 and December 2002, TAE for nonvariceal upper gastrointestinal bleeding was performed in 93 patients. The endoscopic approach had failed or was discarded as an approach for control of bleeding in all study patients. Among the 93 patients NBCA was used as the primary embolic

3
논문|인용수 56·2010
The Role of Perfusion CT as a Follow-up Modality After Transcatheter Arterial Chemoembolization
Seung Hong Choi, Jin Wook Chung, Hyo‐Cheol Kim, Jin Baek, Chang Min Park, Suryoung Jun, Min Uk Kim, Eun Sun Lee, Hye Rim Cho, Hwan Jun Jae, Whal Lee, Jae Hyung Park
SJR Q1FWCI 5.2Investigative Radiology

We believe that perfusion CT is a feasible alternative modality for the successful early response assessment and early detection of a marginally recurred tumor after TACE. However, perfusion CT has limitations for the prediction of tumor recurrence after TACE.

Radiology, Nuclear Medicine and ImagingMedicine
4
논문|인용수 45·2008
Experimental Study on Acute Ischemic Small Bowel Changes Induced by Superselective Embolization of Superior Mesenteric Artery Branches with N-Butyl Cyanoacrylate
Hwan Jun Jae, Jin Wook Chung, Hyo‐Cheol Kim, Young So, Hyung Guhn Lim, Whal Lee, Byoung Kwon Kim, Jae Hyung Park
SJR Q2FWCI 1.1Journal of Vascular and Interventional RadiologyOA
GastroenterologyMedicine
5
논문|인용수 41·2016
pH-Sensitive sulfamethazine-based hydrogels as potential embolic agents for transcatheter vascular embolization
Quang Vinh Nguyễn, Myung Su Lee, Jae Seung Lym, Young Il Kim, Hwan Jun Jae, Doo Sung Lee
SJR Q1FWCI 0.8Journal of Materials Chemistry B

After delivery through a catheter, a three-dimensional hydrogel network was formed upon the change of environmental pH, and thus block the targeted blood vessels, as presented in white color under the fluoroscopic angiogram.

Molecular MedicineBiochemistry, Genetics and Molecular Biology
6
논문|인용수 40·2009
The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model
Hwan Jun Jae, Jin Wook Chung, Hee Sun Park, Min Jong Lee, Ki Chang Lee, Hyo‐Cheol Kim, Jung‐Hwan Yoon, Hesson Chung, Jae Hyung Park
SJR Q1FWCI 0.7Korean Journal of RadiologyOA

Even though intraarterial delivery of 3-BrPA shows a dose-related antitumor effect, single session treatment seems to have limited efficacy when compared with the conventional method.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
7
논문|인용수 32·2017
Superselective Embolization for Arterial Upper Gastrointestinal Bleeding Using N -Butyl Cyanoacrylate: A Single-Center Experience in 152 Patients
Saebeom Hur, Hwan Jun Jae, Hyukjoon Lee, Myungsu Lee, Hyo‐Cheol Kim, Jin Wook Chung
SJR Q2FWCI 2.4Journal of Vascular and Interventional Radiology
GastroenterologyMedicine
8
논문|인용수 31·2007
Chronic-Stage Deep Vein Thrombosis of the Lower Extremities
Eun‐Ah Park, Whal Lee, Min Woo Lee, Sang-Il Choi, Hwan Jun Jae, Jin Wook Chung, Jai Hyung Park
SJR Q3FWCI 0.8Journal of Computer Assisted Tomography

Luminal obliteration, decreased caliber, fibrotic bands, ipsilateral muscle enlargement, and superficial collateral vein development are common CT findings in chronic DVT of the lower extremity.

Internal MedicineMedicine
9
논문|인용수 29·2007
Preoperative Evaluation of Lower Extremity Arteries for Free Fibula Transfer Using MDCT Angiography
Kwang Nam Jin, Whal Lee, Yong Yin, Sang-Il Choi, Hwan Jun Jae, Jin Wook Chung, Jae Hyung Park
SJR Q3FWCI 1.7Journal of Computer Assisted Tomography

Computed tomographic angiography is a reliable preoperative imaging technique for the selection of appropriate legs as candidates for fibular free transfer.

SurgeryMedicine
10
논문|인용수 25·2011
Transcatheter Arterial Embolization of Intramuscular Active Hemorrhage with N-Butyl Cyanoacrylate
Dong Hyun Yoo, Hwan Jun Jae, Hyo‐Cheol Kim, Jin Wook Chung, Jae Hyung Park
SJR Q2FWCI 2.1CardioVascular and Interventional Radiology
SurgeryMedicine
11
논문|인용수 22·2007
Follow-up CT Evaluation of the Mural Changes in Active Takayasu Arteritis
제환준, 박재형, 정진욱, 김효철, 이활, 소영호, 김상영

Objective: We wanted to evaluate the mural changes by CT on the follow-up examination of patients with active Takayasu arteritis. Materials and Methods: The study included 18 patients, (4 males and 14 females), with active Takayasu arteritis. A total of 44 CT examinations were done during the follow-up period (mean: 55.6 months). At the time of the last follow-up CT, the disease, on the basis of the erythrocyte sedimentation rate (ESR), was found to be inactive in five patients and the disease w

12
논문|인용수 16·2009
The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model
제환준, 정진욱, 이민종, 김효철, 윤정환, 정혜선, 박재형, 이기창, 박희선

Objective: The purpose of this study was to compare the antitumor effect and hepatotoxicity of an intraarterial delivery of low-dose and high-dose 3-bromopyruvate (3-BrPA) and those of a conventional Lipiodol-doxorubicin emulsion in a rabbit VX2 hepatoma model. Materials and Methods: This experiment was approved by the animal care committee at our institution. VX2 carcinoma was implanted in the livers of 36 rabbits. Transcatheter intraarterial administration was performed using low dose 3- BrPA

13
논문|인용수 14·2008
Cardiovascular Behcet Disease
Young Kwon Cho, Whal Lee, Sang Il Choi, Hwan Jun Jae, Jin Wook Chung, Jae Hyung Park
SJR Q3FWCI 1.6Journal of Computer Assisted Tomography

Unusual radiological manifestations of rare complications of cardiovascular Behcet disease (BD) are the following: (a) aneurysm and (b) occlusion in the aorta and its major branches, (c) pseudoaneurysms on the aortic root and coronary artery, and recurrent valvular dehiscence in the heart, (d) venous thrombosis in the deep and superficial venous system and vena cava. The initial exact diagnosis of cardiovascular BD has been extremely difficult for these rare complicated findings, especially in t

OphthalmologyMedicine
14
논문|인용수 9·2021
Biodegradable poly(lactide-co-glycolide) microspheres encapsulating hydrophobic contrast agents for transarterial chemoembolization
Seong Ik Jeon, Moo Song Kim, Hyung‐Jun Kim, Young‐Il Kim, Hwan Jun Jae, Cheol-Hee Ahn
SJR Q2FWCI 0.8Journal of Biomaterials Science Polymer Edition

Transarterial chemoembolization (TACE) is a therapeutic approach to address hepatocellular carcinoma by obstructing the blood supply to the tumor using embolic agents and improving the local delivery of anticancer agents. Size-calibrated polymeric microspheres (MSs) termed drug-eluting beads (DEBs) are the most prevalent solid embolic materials; however, their limitations include insufficient X-ray visibility or biodegradability. In this study, size-controlled polymeric MSs with inherent radiopa

HepatologyMedicine
15
논문|인용수 2·2024
Iodinated Cyanoacrylate‐Based Novel Liquid Embolic Compositions with Inherent Radiopacity for Endovascular Embolization
Seong Ik Jeon, Hyunjae Park, Hanhee Cho, Saebeom Hur, Young Il Kim, Hwan Jun Jae, Cheol‐Hee Ahn
SJR Q1FWCI 0.7Advanced Healthcare MaterialsOA

Endovascular embolization is a promising therapeutic approach broadening its application area due to its minimal invasiveness and short operation time, wherein lesional blood vessels are occluded with liquid embolic agents under X-ray imaging guidance. Histoacryl and its composition with Lipiodol are one of the most widely used liquid embolic agents, however, Histoacryl has critical limitations, such as lack of innate X-ray visibility and strong adhesion to microcatheter. In this study, three di

NeurologyMedicine

대표 연구 분야

HepatologySurgeryPulmonary and Respiratory MedicineInternal MedicineGastroenterologyGenetics

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