서혜연 교수
Hye-Yeon Seo
서울대학교 · 의학
연구실 소개
서혜연 교수의 연구실은 암 환자의 삶의 질 향상을 목표로 하며, 특히 암 생존자 간호사의 간호 실천과 유전성 유방암에 대한 환자 인지 수준, 그리고 항암 치료 후 유전자 기반 면역치료제의 안전성과 효과를 중심으로 연구를 진행하고 있습니다. 최근에는 신체 내 내재된 유황 기반 기체전달물질인 황화수소(H₂S)를 탐지할 수 있는 PET 영상 진단 기술 개발에도 주력하고 있습니다. 이는 염증 및 저산소 상태에서의 병태생리적 변화를 정량적으로 평가하는 데 기여할 것으로 기대됩니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
6Purpose: The purpose of this study was to examine the cancer survivorship care practices among oncology nurses in Korea. Methods: This study was a secondary analysis based on the Korean data from the international service-mapping study for the survivorship care for patients with cancer after treatment completion in the Asia-Pacific Region. The data, collected from 100 Korean nurses who took care of cancer patients, were analyzed using descriptive statistics, t-test, ANOVA, Pearson’s correlation
Purpose: The purpose of the study was to understand the levels of knowledge about hereditary breast cancer and anxiety among patients with breast cancer and to identify the relationship between knowledge and anxiety. Methods: The data were collected from 100 patients with breast cancer in Seoul in 2013. A 15-item hereditary breast cancer knowledge questionnaire and 20-item anxiety state questionnaire were used to measure knowledge and anxiety, respectively. The data were analyzed using descripti
Background: BVAC-C is a B cell- and monocyte-based immunotherapeutic vaccine transfected with recombinant HPV E6/E7 gene and loaded with alpha-galactosyl ceramide, a natural killer T cell ligand. It may have activity against HPV positive cancer. This phase I study was performed to determine the safety and tolerability of BVAC-C in patients with HPV type 16 or 18 positive recurrent cervical carcinoma and to preliminarily assess antitumor activity and immunologic correlates. Methods: Ten patients
Hydrogen sulfide (H2S), recognized as the third gasotransmitter with specific implications for inflammation and hypoxia, exhibits affinity for 64Cu immobilization. This study explores the viability of 64Cu-labeled PET tracers in detecting endogenous H2S. In vitro reactivity experiments involved evaluating the interaction between various concentrations of NaHS and 64Cu-labeled chelators at 37℃ in a shaking incubator. In vivo molecular PET imaging studies were conducted using two distinct mouse mo
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