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오현정 교수

Hyeon Jeong Oh

서울대학교 · 의학

연구실 소개

오현정 교수의 연구실은 대장암의 예후 예측 생물학적 마커와 종양 미세환경의 분자 기전을 중심으로 연구를 진행하고 있습니다. 특히, POSTN, F. nucleatum, p53, HSP110 등의 생체마커가 암 진행과 치료 반응에 미치는 영향을 분석하며, 마이크로환경의 이질성과 관련된 분자 조절 메커니즘을 규명하고자 합니다. 또한, 미네랄인 zinc이 치아 형성과 뼈 발달에 미치는 영향을 다루며, 세포 신호전달과 발달 조절 경로의 상호작용을 탐구하고 있습니다.

대장암 예후 마커장내 미생물HSP110p53아연 대사

연구 현황

논문 수
105
총 인용 수
1,141
최근 5년 논문
44
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
44총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
283총합
20222023202420252026

주요 논문

15
1
논문|인용수 71·2014
CPNE7, a preameloblast-derived factor, regulates odontoblastic differentiation of mesenchymal stem cells
Hyunjung Oh, Han‐Wool Choung, Hye‐Kyung Lee, Sujin Park, Jihyun Lee, Dong‐Seol Lee, Byoung‐Moo Seo, Joo‐Cheol Park
SJR Q1FWCI 1.4Biomaterials
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
논문|인용수 66·2017
Overexpression of POSTN in Tumor Stroma Is a Poor Prognostic Indicator of Colorectal Cancer
Hyeon Jeong Oh, Jeong Mo Bae, Xian-Yu Wen, Nam‐Yun Cho, Jung Ho Kim, Gyeong Hoon Kang
SJR Q2FWCI 5.1Journal of Pathology and Translational MedicineOA

Our findings suggest that POSTN overexpression in tumor stroma of colorectal cancers could be a possible candidate marker for predicting poor prognosis in patients with colorectal cancers.

Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 60·2018
Prognostic Impact of <i>Fusobacterium nucleatum</i> Depends on Combined Tumor Location and Microsatellite Instability Status in Stage II/III Colorectal Cancers Treated with Adjuvant Chemotherapy
Hyeon Jeong Oh, Jung Ho Kim, Jeong Mo Bae, Hyun Jung Kim, Nam-Yun Cho, Gyeong Hoon Kang
SJR Q2FWCI 2.1Journal of Pathology and Translational MedicineOA

Intratumoral F. nucleatum load is a potential prognosticfactor in a non-MSI-high/non-sigmoid/non-rectal cancer subset of stage II/III CRCs treatedwith oxaliplatin-based adjuvant chemotherapy.

OncologyMedicine
4
논문|인용수 50·2019
p53 expression status is associated with cancer-specific survival in stage III and high-risk stage II colorectal cancer patients treated with oxaliplatin-based adjuvant chemotherapy
Hyeon Jeong Oh, Jeong Mo Bae, Xianyu Wen, Seorin Jung, Young-Hoon Kim, Kyung Ju Kim, Nam‐Yun Cho, Jung Ho Kim, Sae‐Won Han, Tae‐You Kim, Gyeong Hoon Kang
SJR Q1FWCI 4.5British Journal of CancerOA

p53-mild expression status was found to be an independent prognostic marker in adjuvant FOLFOX-treated patients with stage III and high-risk stage II CRC.

Pathology and Forensic MedicineMedicine
5
논문|인용수 29·2011
Zinc balance is critical for NFI‐C mediated regulation of odontoblast differentiation
Hyunjung Oh, Hye‐Kyung Lee, Sujin Park, Young‐Sik Cho, Hyun‐Sook Bae, Moon‐Il Cho, Joo‐Cheol Park
SJR Q2FWCI 1.8Journal of Cellular Biochemistry

Zinc is trace element essential for diverse metabolic and cellular signaling pathways for the growth, development, and maintenance. Zinc deficiency is involved in bone malformations and oral disease. Mice deficient in zinc transporter Zip13 show connective tissue and skeletal disorders, abnormal incisor teeth, and reduced root dentin formation in the molar teeth and share a morphologically similar phenotype to nuclear factor I-C (NFI-C)-deficient mice. However, the precise function of zinc in NF

Nutrition and DieteticsNursing
6
논문|인용수 11·2017
Dominant high expression of wild‐type HSP110 defines a poor prognostic subgroup of colorectal carcinomas with microsatellite instability: a whole‐section immunohistochemical analysis
Hyeon Jeong Oh, Jung Ho Kim, Tae Hun Lee, Hye Eun Park, Jeong Mo Bae, Hye Seung Lee, Gyeong Hoon Kang
SJR Q1FWCI 0.6Apmis

The aim of this study is to establish heat shock protein 110 (HSP110) as a prognostic biomarker of colorectal carcinomas (CRCs) with microsatellite instability-high (MSI-H) by considering the intratumoral heterogeneity of HSP110 expression. We performed whole-section immunohistochemistry (IHC) for wild-type HSP110 (HSP110wt) in 164 MSI-H CRCs. The intensity of the HSP110wt expression in tumor cells was semiquantitatively scored (0/1/2/3), and the HSP110wt expression status of each tumor was clas

Pathology and Forensic MedicineMedicine
7
논문|인용수 7·2014
A Case of Feline Infectious Peritonitis with Intestinal Manifestation in a Cat
Hyunjung Oh, Jungmin Sohn, Sun-Young Jung, Bo-eun Kim, Seoyeoun Ji, Joohyun Jung, Dae-Yong Kim, Hwa‐Young Youn, Junghee Yoon, Mincheol Choi
SJR Q4FWCI 1.7Journal of Veterinary Clinics

Hyun-jung Oh, Jung-min Sohn, Sun-young Jung, Bo-eun Kim, Seo-yeoun JI, Joo-hyun Jung, Dae-yong Kim, Hwa-young Youn, Junghee Yoon and Min-cheol Choi. J Vet Clin 2014;31:449-53. https://doi.org/10.17555/ksvc.2014.10.31.5.449

Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 5·2017
Evaluation of the ureteral jet in dogs by using color Doppler ultrasonography
Hyunjung Oh, Seong-Soo Kim, Suyeon Kim, Jeosoon Lee, Sookyung Yun, Junghee Yoon, Joohyun Jung, Mincheol Choi
SJR Q2FWCI 0.8Journal of Veterinary ScienceOA

Ureteral jets are the result of a forceful ejection of urine from the vesicoureteral junction into the urinary bladder. By using color Doppler ultrasonography (US), we aimed to identify distinct ureteral jets in dogs, provide insight into ureteral obstruction, and facilitate study of urodynamics and vesicoureteric sphincter function via pulsed Doppler US. Color Doppler US was applied to detect urinary flow from the right ureteral orifices in eight healthy beagles. Under anesthesia, 0.9% saline (

Pediatrics, Perinatology and Child HealthMedicine
9
논문|인용수 3·2014
Ultrasonographic features of spontaneous breast tumor infarction
Hyeon Jeong Oh, Sung Hun Kim, Bong Joo Kang, A. Won Lee, Byung Joo Song, Hyen Sook Kim, Eun Suk
SJR Q1FWCI 0.6Breast Cancer
Pathology and Forensic MedicineMedicine
10
논문|인용수 2·2023
Development of a New Measurement System for Piston Ring Friction Based on the Floating Liner Method
Hyunjung Oh, Kyoung-Pyo Ha, Kyoungdoug Min
SJR Q2FWCI 0.3International Journal of Automotive Technology
Mechanical EngineeringEngineering
11
논문|인용수 1·2025
High-Throughput Chemotherapeutic Drug Screening System for Gastric Cancer (Cure-GA)
Jieun Lee, In Hee Kim, Donghyeok Seol, Sang Jun Lee, Mira Yoo, Tae‐Kyeong Lee, So Hee Yoon, Eun‐Ju Lee, Duyeong Hwang, So Hyun Kang, Young Suk Park, Bosung Ku
SJR Q1FWCI 1.0Annals of Surgical OncologyOA

The Cure-GA platform enables rapid evaluation of chemotherapeutic responses using patient-derived tumoroids, providing clinicians with crucial insights for personalized treatment strategies and improving therapeutic outcomes.

OncologyMedicine
12
논문|인용수 1·2014
Relationship Between Modified CT Severity Index and Clinical Features of L-Asparaginase-Associated Pancreatitis in Pediatric Acute Lymphoblastic Leukemia
Hyeon Jeong Oh, Soo Ah Im, Jae Wook Lee, Nak Gyun Chung, Bin Cho
SJR Q3FWCI 0.3Pediatric Hematology and Oncology

In L-AP with pediatric ALL patients, MCSI may correlate with usage of IV narcotics, BUN, and peak amylase levels.

SurgeryMedicine
13
dissertation|인용수 0·2004
(The)Effect of TPO (thyroid peroxidase) gene transfection on radioiodide kinetics in ARO-NIS cells
오현정
Seoul National University Open Repository (Seoul National University)
Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 0·2025
Diagnosis and management of Brugada Syndrome Unmasked by Flecainide challenge in a patient with unexplained ventricular fibrillation: a case report
Hyeon Jeong Oh, Hyun Cho, Kyu-Yong Ko, Sung Eun Kim, Sung Woo Cho, Jae Jin Kwak, Jiwon Hwang
SJR Q4Oxford Medical Case ReportsOA

This case underscores the importance of considering Brugada syndrome in patients with unexplained ventricular fibrillation, emphasizing the utility of the flecainide challenge test for accurate diagnosis when characteristic ECG findings are not evident.A multidisciplinary approach, including timely diagnosis, appropriate ICD implantation, and patient education, is critical in managing high-risk occupations to prevent catastrophic outcomes.

Cardiology and Cardiovascular MedicineMedicine

대표 연구 분야

OncologyPulmonary and Respiratory MedicineMolecular BiologySurgeryPathology and Forensic MedicineCardiology and Cardiovascular Medicine

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