김현지 교수

Self-report questionnaires are the most commonly used personality assessment despite longstanding concerns that self-report responses may be distorted by self-protecting motives and response biases. In a large-scale meta-analysis ( N = 33,033; k = 152 samples), we compared the means of self- and informant reports of the same target's Big Five personality traits to examine the discrepancies in two rating sources and whether people see themselves more positively than they are seen by others. Incon

The findings attest to the moderating role of culture on Extraversion and life satisfaction and the importance of controlling for shared method variance.

Anusic, Schimmack, Pinkus, and Lockwood (2009) developed the halo-alpha-beta (HAB) model to separate halo variance from variance due to valid personality traits and other sources of measurement error in self-ratings of personality. The authors used a twin-HAB model of self-ratings and ratings of a partner (friend or dating partner) to test several hypotheses about culture, evaluative biases in self- and other-perceptions, and well-being. Participants were friends or dating partners who reported

Metastasis is one of hallmarks of cancer and a major cause of cancer death. Combatting metastasis is highly challenging. To overcome these difficulties, researchers have focused on physical properties of metastatic cancer cells. Metastatic cancer cells from patients are softer than benign cancer or normal cells. Changes of viscoelasticity of cancer cells are related to the keratin network. Unexpectedly, keratin network is dynamic and regulation of keratin network is important to the metastasis o

Inlay butterfly cartilage tympanoplasty is compatible with the conventional underlay technique in both anatomic and functional success rates. Its simplicity, shorter operation time, and rapid recovery time could make it an attractive surgical option.

We previously demonstrated that kainic acid (KA)-mediated mitochondrial oxidative stress contributed to hippocampal degeneration and that ginsenosides attenuated KA-induced neurotoxicity and neuronal degeneration. Here, we examined whether ginsenosides affected KA-induced mitochondrial dysfunction and oxidative stress in the rat hippocampus. Treatment with ginsenosides attenuated KA-induced convulsive behavior dose-dependently. KA treatment increased lipid peroxidation and protein oxidation and

Online learning is rapidly developing, and various strategies to effectively operate online learning are being discussed. In particular, online learning using the metaverse is expected to facilitate social communication and high presence. This study examined the presence and effectiveness of online learning using a metaverse platform. A class was conducted for six weeks using the metaverse platform Gather.town. A questionnaire was employed to verify the online presence of the learners and the ef

ARG2 has been reported to inhibit autophagy in vascular endothelial cells and keratinocytes. However, studies of its mechanism of action, its role in skin fibroblasts, and the possibility of promoting autophagy and inhibiting cellular senescence through ARG2 inhibition are lacking. We induced cellular senescence in dermal fibroblasts by using H₂O₂. H₂O₂-induced fibroblast senescence was inhibited upon ARG2 knockdown and promoted upon ARG2 overexpressio

The high mortality rates associated with cancer reflect the metastatic spread of tumor cells from the site of their origin. Metastasis, in fact, is the cause of 90% of cancer deaths. Therefore, considerable effort is being made to inhibit metastasis. In the present study, we screened ketotifen for anti-migratory and anti-invasive activities against MDA-MB-231 breast cancer and HT-1080 fibrosarcoma cancer cells. Cancer cell migration and invasion were measured using multi-well chambers. Additiona

Past studies have shown that North Americans have higher well-being compared with East Asians. Objective living conditions (e.g., wealth, education, personal and political freedom) have been found to substantially contribute to North Americans’ higher well-being. One other possible explanation is that North American culture fosters positive evaluations of the self to enhance self-esteem and to feel positive emotions, which may lead North Americans to provide favorable ratings. These cultural dif

LW1497 suppresses the expression of the hypoxia-inducing factor (HIF)-1α inhibiting malate dehydrogenase. Although hypoxia and HIF-1α are known to be important in cancer, LW1497 has not been therapeutically applied to cancer yet. Thus, we investigated the effect of LW1497 on the epithelial-mesenchymal transition (EMT) of lung cancer cells. A549 and H1299 lung cancer cells were induced to undergo via TGF-β1 treatment, resulting in the downregulation of E-cadherin and upregulation of N-cadherin an

Sphingosylphosphorylcholine induces keratin phosphorylation and reorganization, and increases viscoelasticity of metastatic cancer cells such as PANC-1 cells. However, the mechanism involved in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization is largely unknown. Sphingosylphosphorylcholine dose- and time-dependently induces the expression of RhebL1. The involvement of RhebL1 in sphingosylphosphorylcholine-induced events including keratin 8 (K8) phosphorylation, reor