강효진 교수
Hyo-Jin Kang
서울대학교 · 의학
연구실 소개
강효진 교수의 연구실은 신경종양의 영상진단 및 수술적 치료 전략 개발에 초점을 맞추고 있으며, 특히 상지 신경鞘종양의 임상적 특성과 MRI 영상 소견을 체계적으로 분석하고 있습니다. 또한, 산화 스트레스와 관련된 전사 인자 NRF2의 조절 메커니즘을 규명함으로써 당뇨, 암 등 만성질환의 새로운 치료 타겟을 모색하고 있습니다. 최근에는 압축 센싱 기반 고속 MRI 기술을 활용한 정밀 영상 진단 기법의 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Background Hepatocellular carcinomas (HCCs) are heterogeneous neoplasms, and the prognosis varies based on the subtype. Two broad molecular classes of HCC have been proposed: a proliferative and a nonproliferative class. Purpose To evaluate the gadoxetate-enhanced MRI findings of the proliferative class HCC and its prognostic significance after surgery. Materials and Methods This retrospective cohort study evaluated patients with surgically resected treatment-naive single HCC (≤5 cm) who underwe
Compressed sensing MRCP using incoherent undersampling combined with CS reconstruction provided comparable image quality to conventional MRCP while reducing the acquisition time to within a single breath-hold (16 seconds).
The diagnostic performance of multidetector CT and MR imaging with MRCP for identifying the malignant potential of pancreatic IPMNs was similar and showed good intermodality agreement, suggesting that follow-up with either modality may be used.
Background Perfluorobutane (PFB) and sulfur hexafluoride (SHF) have different physiologic characteristics, but it is unclear whether hepatocellular carcinomas (HCCs) show similar wash-in and washout patterns to both contrast agents at US. Purpose To investigate Contrast-Enhanced US Liver Imaging Reporting and Data System (LI-RADS) version 2017 HCC categorization by comparing PFB-enhanced US and SHF-enhanced US in participants at high risk for HCC. Materials and Methods In this prospective study
Objective: To determine the feasibility of microvascular flow imaging (MVFI) in comparison with color/power Doppler imaging (CDI/PDI) for detection of intratumoral vascularity in suspected post-transarterial chemoembolization (TACE) residual or recurrent hepatocellular carcinomas (HCCs) by using contrast-enhanced ultrasonography (CEUS) or hepatic angiography (HA) findings as the reference standard. Materials and Methods: One hundred HCCs (mean size, 2.2 cm) in 100 patients treated with TACE were
Adding CEUS to APNHE observations from CT/MRI would be useful not only for definitely diagnosing HCC (CEUS LR-5) but also for other malignancies (CEUS LR-M). The discordance of dynamic features between the LI-RADS for CEUS and CT/MRI may reflect the different properties of contrast media, although the systems are not interchangeable.
The aMRI-BH provided high sensitivity and negative predictive value to evaluate malignant IPMNs by using predetermined criteria, and aMRI-BH might be a potential tool for pancreatic IPMN surveillance with significantly lower acquisition time.
Statistical models of shape and appearance have been successfully used in face modeling, tracking and synthesis. In this paper we describe experiments using appearance models for face verification. We compare a variety of different algorithms on a standard face database (XM2VTS). We demonstrate that simple methods of correction for head pose and face expression can significantly improve results.
The addition of CEUS to Gd-EOB-MRI as a second-line diagnostic modality increases the frequency of HCC diagnosis without changing the specificities.
SZUS was noninferior to SVUS for diagnosing HCC in at-risk patients using the same diagnostic criteria. No significant improvement in HCC diagnosis was observed by extending the washout time delay from 5 to 10 minutes.
Isotropic high-resolution T1W-MRCs with ID provided significantly improved BD image quality and more accurate depiction of the BD anatomy and BD openings at right donor hemihepatetomy than 3D-T2W-MRC.
Determining washout within 6 minutes after contrast injection with a 60-second cutoff for late washout showed the highest sensitivity without losing specificity for diagnosing HCC using PFB-US in individuals at high risk.
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