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이형철 교수

Hyung Chul Lee

서울대학교 · 의학

연구실 소개

이 교수의 연구실은 마취 과정 중 수집되는 고해상도 생체신호 데이터의 정밀한 기록과 분석을 핵심으로 하며, 특히 애널레시아 인포메이션 관리 시스템(AIMS)의 한계를 보완하기 위한 전용 기록 소프트웨어 '바이탈 레코더' 개발로 출발했습니다. 생체신호 데이터베이스(VitalDB)를 구축하여 기계학습 기반의 생체신호 분석 연구를 활성화하고, 심장·간 이식 수술 후 급성 신손상(AKI) 예측 모델 개발을 위해 머신러닝 기법(랜덤 포레스트, 그래디언트 부스팅 등)과 전통적 회귀분석을 비교·적용하고 있습니다. 특히 딥러닝 기반의 뇌전도 지수(BIS) 예측 모델 개발을 통해 마취 약물 동역학 예측의 정확도를 향상시키는 데도 기여하고 있습니다.

생체신호 분석기계학습AKI 예측바이탈DB딥러닝 마취 모델

연구 현황

논문 수
277
총 인용 수
4,582
최근 5년 논문
88
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
88총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
962총합
20222023202420252026

주요 논문

15
1
논문|인용수 235·2018
Vital Recorder—a free research tool for automatic recording of high-resolution time-synchronised physiological data from multiple anaesthesia devices
Hyung‐Chul Lee, Chul-Woo Jung
SJR Q1FWCI 16.1Scientific ReportsOA

The current anaesthesia information management system (AIMS) has limited capability for the acquisition of high-quality vital signs data. We have developed a Vital Recorder program to overcome the disadvantages of AIMS and to support research. Physiological data of surgical patients were collected from 10 operating rooms using the Vital Recorder. The basic equipment used were a patient monitor, the anaesthesia machine, and the bispectral index (BIS) monitor. Infusion pumps, cardiac output monito

SurgeryMedicine
2
논문|인용수 196·2018
Prediction of Acute Kidney Injury after Liver Transplantation: Machine Learning Approaches vs. Logistic Regression Model
Hyung‐Chul Lee, Soo Bin Yoon, Seong Mi Yang, Won Ho Kim, Ho Geol Ryu, Chul-Woo Jung, Kyung‐Suk Suh, Kook Hyun Lee
SJR Q1FWCI 19.6Journal of Clinical MedicineOA

Acute kidney injury (AKI) after liver transplantation has been reported to be associated with increased mortality. Recently, machine learning approaches were reported to have better predictive ability than the classic statistical analysis. We compared the performance of machine learning approaches with that of logistic regression analysis to predict AKI after liver transplantation. We reviewed 1211 patients and preoperative and intraoperative anesthesia and surgery-related variables were obtaine

SurgeryMedicine
3
논문|인용수 194·2022
VitalDB, a high-fidelity multi-parameter vital signs database in surgical patients
Hyung‐Chul Lee, Yoonsang Park, Soo Bin Yoon, Seong Mi Yang, Dongnyeok Park, Chul-Woo Jung
SJR Q1FWCI 23.6Scientific DataOA

In modern anesthesia, multiple medical devices are used simultaneously to comprehensively monitor real-time vital signs to optimize patient care and improve surgical outcomes. However, interpreting the dynamic changes of time-series biosignals and their correlations is a difficult task even for experienced anesthesiologists. Recent advanced machine learning technologies have shown promising results in biosignal analysis, however, research and development in this area is relatively slow due to th

Artificial IntelligenceComputer Science
4
논문|인용수 192·2018
Derivation and Validation of Machine Learning Approaches to Predict Acute Kidney Injury after Cardiac Surgery
Hyung‐Chul Lee, Hyun‐Kyu Yoon, Karam Nam, Youn Joung Cho, Tae Kyong Kim, Won Ho Kim, Jae-Hyon Bahk
SJR Q1FWCI 11.6Journal of Clinical MedicineOA

Machine learning approaches were introduced for better or comparable predictive ability than statistical analysis to predict postoperative outcomes. We sought to compare the performance of machine learning approaches with that of logistic regression analysis to predict acute kidney injury after cardiac surgery. We retrospectively reviewed 2010 patients who underwent open heart surgery and thoracic aortic surgery. Baseline medical condition, intraoperative anesthesia, and surgery-related data wer

Cardiology and Cardiovascular MedicineMedicine
5
논문|인용수 127·2017
Prediction of Bispectral Index during Target-controlled Infusion of Propofol and Remifentanil
Hyung‐Chul Lee, Ho Geol Ryu, Eun-Jin Chung, Chul-Woo Jung
SJR Q1FWCI 13.3Anesthesiology

The deep learning model-predicted bispectral index during target-controlled infusion of propofol and remifentanil more accurately compared to the traditional model. The deep learning approach in anesthetic pharmacology seems promising because of its excellent performance and extensibility.

Anesthesiology and Pain MedicineMedicine
6
논문|인용수 90·2010
Activation of vascular BK channels by docosahexaenoic acid is dependent on cytochrome P450 epoxygenase activity
Ruxing Wang, Qing Chai, Tong Lü, Hyung‐Chul Lee
SJR Q1FWCI 5.5Cardiovascular ResearchOA

These results suggest that DHA-mediated vasodilatation is mediated through CYP epoxygenase metabolites by activation of vascular BK channels.

BiochemistryBiochemistry, Genetics and Molecular Biology
7
논문|인용수 56·2013
Higher operating tables provide better laryngeal views for tracheal intubation
Hyung‐Chul Lee, Mi-Jung Yun, Jung‐Won Hwang, H.-S. Na, D.-H. Kim, J.-Y. Park
SJR Q1FWCI 3.3British Journal of Anaesthesia
Anesthesiology and Pain MedicineMedicine
8
논문|인용수 55·2019
Intraoperative Arterial Pressure Variability and Postoperative Acute Kidney Injury
Sehoon Park, Hyung‐Chul Lee, Chul-Woo Jung, Yunhee Choi, Hyung Jin Yoon, Sejoong Kim, Ho Jun Chin, Myeong-Seok Kim, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim
SJR Q1FWCI 4.0Clinical Journal of the American Society of NephrologyOA

Higher intraoperative BP variability is associated with higher risks of postoperative AKI after noncardiac surgery, independent of hypotension and other clinical characteristics.

SurgeryMedicine
9
논문|인용수 41·2019
Data Driven Investigation of Bispectral Index Algorithm
Hyung‐Chul Lee, Ho Geol Ryu, Yoonsang Park, Soo Bin Yoon, Seong Mi Yang, Hye‐Won Oh, Chul-Woo Jung
SJR Q1FWCI 5.1Scientific ReportsOA

Bispectral index (BIS), a useful marker of anaesthetic depth, is calculated by a statistical multivariate model using nonlinear functions of electroencephalography-based subparameters. However, only a portion of the proprietary algorithm has been identified. We investigated the BIS algorithm using clinical big data and machine learning techniques. Retrospective data from 5,427 patients who underwent BIS monitoring during general anaesthesia were used, of which 80% and 20% were used as training d

Anesthesiology and Pain MedicineMedicine
10
논문|인용수 40·2024
INSPIRE, a publicly available research dataset for perioperative medicine
Leerang Lim, Hyeonhoon Lee, Chul-Woo Jung, Dayeon Sim, X. Borrat, Tom Pollard, Leo Anthony Celi, Roger G. Mark, Simon Tilma Vistisen, Hyung‐Chul Lee
SJR Q1FWCI 16.1Scientific DataOA

We present the INSPIRE dataset, a publicly available research dataset in perioperative medicine, which includes approximately 130,000 surgical operations at an academic institution in South Korea over a ten-year period between 2011 and 2020. This comprehensive dataset includes patient characteristics such as age, sex, American Society of Anesthesiologists physical status classification, diagnosis, surgical procedure code, department, and type of anaesthesia. The dataset also includes vital signs

Cardiology and Cardiovascular MedicineMedicine
11
book|인용수 35·2016
Can Electronic Tax Invoicing Improve Tax Compliance? A Case Study of the Republic of Korea's Electronic Tax Invoicing for Value-Added Tax
Hyung‐Chul Lee
FWCI 1.7World Bank, Washington, DC eBooksOA

This paper reviews the Republic of Korea's experience with electronic tax invoices for its value-added tax regime from the perspectives of tax policy makers and administrators. The paper evaluates Korea's implementation of electronic tax invoicing and analyzes its effect on tax compliance through enhanced transparency of business transactions and taxpayer services. First implemented in 2011, mandatory electronic tax invoicing has been credited with lowering tax compliance costs and raising the t

Economics and EconometricsEconomics, Econometrics and Finance
12
논문|인용수 34·2022
Development and Validation of a Prediction Model for Need for Massive Transfusion During Surgery Using Intraoperative Hemodynamic Monitoring Data
Seung Mi Lee, Garam Lee, Tae Kyong Kim, Trang T. Le, Jie Hao, Young Mi Jung, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Hyung‐Chul Lee, Dokyoon Kim
SJR Q1FWCI 5.0JAMA Network OpenOA

The findings of this prognostic study suggest that the real-time prediction model for massive transfusion showed high accuracy of prediction performance, enabling early intervention for high-risk patients. It suggests strong confidence in artificial intelligence-assisted clinical decision support systems in the operating field.

Critical Care and Intensive Care MedicineMedicine
13
논문|인용수 29·2019
McGrath MAC Videolaryngoscope Versus Optiscope Video Stylet for Tracheal Intubation in Patients With Manual Inline Cervical Stabilization: A Randomized Trial
Hyun‐Kyu Yoon, Hyung‐Chul Lee, Jung‐Bin Park, Hyongmin Oh, Hee‐Pyoung Park
SJR Q1FWCI 5.1Anesthesia & Analgesia

The McGrath MAC videolaryngoscope showed a higher first-attempt success rate for tracheal intubation and a shorter intubation time than the Optiscope video stylet in cervical spine patients with manual inline stabilization during tracheal intubation. These results suggest that the McGrath MAC videolaryngoscope may be a better option for tracheal intubation in such patients.

Anesthesiology and Pain MedicineMedicine
14
논문|인용수 29·2017
Radiographic Predictors of Difficult Laryngoscopy in Acromegaly Patients
Hyung‐Chul Lee, Min-Kyung Kim, Yong Hwy Kim, Hee‐Pyoung Park
SJR Q2FWCI 1.1Journal of Neurosurgical Anesthesiology

Old age and radiographic predictors indicating large tongue size (large TA, long alveolar line of the mandible to the hyoid bone and mandible to the hyoid bone) were associated with an increased rate of difficult laryngoscopy in acromegaly patients. Preoperative radiographic measurements of tongue size can be helpful for safe airway management in such patients.

Endocrinology, Diabetes and MetabolismMedicine
15
논문|인용수 21·2002
In vivo effects of Panax ginseng extracts on the cytochrome P450-dependent monooxygenase system in the liver of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed guinea pig
Hyung‐Chul Lee, Sang‐Gu Hwang, Young-Gu Lee, Hyung-Ok Sohn, Dong-Wook Lee, Seok-Youn Hwang, Y. S. Kwak, Jae‐Joon Wee, Woo‐Hong Joo, Yong-Kweon Cho, Ja-Young Moon
SJR Q1FWCI 0.2Life Sciences
Molecular BiologyBiochemistry, Genetics and Molecular Biology

대표 연구 분야

SurgeryAnesthesiology and Pain MedicineCardiology and Cardiovascular MedicinePhysiologyPulmonary and Respiratory MedicineEpidemiology

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