이재혁 교수

An inflammatory cell reaction at the tumor invasive border is considered a useful predictor of survival after colorectal cancer surgery, particularly for patients with stage III disease or rectal cancer.

This study was performed to evaluate the association of monocyte counts with mortality, the rate of bacteremia, and organ dysfunction and to evaluate whether the change in monocyte counts from the premorbid state to sepsis would differ between survivors and non-survivors in patients with severe sepsis including septic shock. A retrospective analysis of patients with severe sepsis including septic shock was performed. Monocyte counts were categorized into <250, 250-500, 500-750, and ≥750 cells/μL

Phyllodes tumors (PTs) of the breast are rare biphasic tumors with the potential for invasion and metastatic spread. Matrix metalloproteinases (MMPs) and their tissue inhibitors of metalloproteinases (TIMPs) are involved in several key aspects of tumoral growth, invasion, and metastasis, but little is known of their expression in PTs. The objective of this study was to assess the expression of MMPs and TIMPs in PTs and to determine their association with grade and clinical behavior of PTs. Eight

Our results suggest that tumor progression in the cervical epithelium is accompanied by loss of PTEN protein expression. Reduced PTEN expression is not associated with tumor angiogenesis of squamous cell carcinoma of the uterine cervix.

Our results suggest that methylation of E-cadherin is a frequent, early event in gastric carcinoma progression, and is correlated significantly with downregulated E-cadherin expression. Inactivation of E-cadherin might be involved in metastasis in EGC and play an important role in microscopic differentiation.

최근 환경에 대한 인식과 관광 산업이 성장하면서 세계적으로 확대되고 있는 생태관광은 지역 발전 전략을 위한 대안으로도 간주되고 있다. 더 나아가 생태관광은 지속가능한 개발을 위한 효과적인 도구로도 잠재성이 있는 것으로까지 인지되고 있다. 그러나 생태관광개발이 잘 계획되지 못하거나 잘못 실행되는 경우 생태관광이란 이름 하에서 가져온 경제적인 이익이 오히려 사회·생태적인 파괴를 가져오기도 한다, 본 연구는 생태관광의 지속가능성을 측정·평가할 수 있는 지표를 개발하고 개발된 평가지표를 한국의 10대 생태관광지에 적용하는데 목적을 두었다. 개발된 평가지표들을 사용한 결과 여러 생태관광지를 동시에 비교하여 생태관광지 마다의 지속가능성 상태와 특성을 확인할 수 있었으며, 개발된 평가지표 체계는 앞으로도 지속가능한 생태관광을 모니터링할 수 있음을 보여주었다. 특히 평가 영역별 가중치를 달리 부여한 결과 나타난 민감도 분석에서 순위 변화가 매우 작아서 평가 영역별 가중치 부여 문제가 심각하지 않을

The current diagnosis of bacteremia mainly relies on blood culture, which is inadequate for the rapid and quantitative determination of most bacteria in blood. Here, a quantitative, multiplex, microfluidic fluorescence in situ hybridization method (μFISH) is developed, which enables early and rapid (3-h) diagnosis of bacteremia without the need for prior blood culture. This novel technology employs mannose-binding lectin-coated magnetic nanoparticles, which effectively opsonize a broad range of

4.

Objective Early defibrillation is crucial for the survival of patients with out-of-hospital cardiac arrest. This study aimed to examine the trends and associated factors regarding public awareness and willingness to use automated external defibrillators (AEDs) through citywide surveys.