신재정 교수

We report the results of an experimental study of the correlations between line edge roughness (LER) and aerial image contrast for different lithographies in identical processing conditions. The characterization has been performed using atomic force microscopy carbon nanotube tips to image the top and bottom of trenches with very high resolution. Experimental results generally support that higher aerial image contrast leads to lower line edge roughness, but differences exist among the lithograph

Argon Fluoride (ArF) lithography is essential to develop a sub-100-nm device, however, line edge roughness (LER) and line width roughness (LWR) is playing a critical role due to the immaturity of photoresist and the lack of etch resistance. Researchers are trying to improve LER and LWR properties by optimizing photoresist materials and process conditions. In this paper, experiment results are presented to study the impact of LER and LWR to device performance so that the reasonable control range

Urokinase plasminogen activator (uPA) belongs to a family of proteins that contains kringle domain and plays an important role in inflammation, tissue remodeling, angiogenesis, and tumor metastasis by pericellular plasminogen activation. Kringle domains of plasminogen have been shown to demonstrate anti-angiogenic and anti-tumor activities. Here, we report our investigation of the kringle domain of uPA for anti-angiogenic activity and a possible cellular mechanism of action. The recombinant krin

Heart failure (HF) has steadily increased in prevalence and affects both males and females equally. Despite this, there has been a significant underrepresentation of women in large scale HF trials. This disparity has lead to a deficit in understanding important gender-based differences in pathophysiology, diagnosis and treatment strategies. We review these gaps and explore a biological basis for varying outcomes. Endogenous estrogen plays an important role in epidemiology and outcome. The admini

In this study, we describe an analytical process for designing a low Earth orbit constellation for discontinuous regional coverage, to be used for a surveillance and reconnaissance space mission. The objective of this study was to configure a satellite constellation that targeted multiple areas near the Korean Peninsula. The constellation design forms part of a discontinuous regional coverage problem with a minimum revisit time. We first introduced an optimal inclination search algorithm to calc

Ubiquitin-specific proteases (USPs) are key regulators of protein homeostasis and have been implicated in various aspects of cancer development, including colorectal cancer (CRC). In this study, we investigated the role of USP11 in CRC pathogenesis. RNA-seq analysis of tumor and matched normal tissues from 35 CRC patients identified USP11 as significantly overexpressed in tumor samples. Elevated USP11 expression was correlated with reduced patient survival, suggesting its prognostic significance

In this paper, we present two improved lossless bounded-real (LBR) two-pair extraction methods using an allpass input function, which significantly reduce roundoff errors during the extraction process and reduce the amount of computation nearly to a half. Both methods are based on the induced allpass transfer function from the given BR function, which is obtained by replacing the value of the terminating multiplier with 1 or -1. The first method is an LBR two-pair extraction based directly on th

Statins reduce coronary vasculopathy and mortality after heart transplantation (HT). However, it remains uncertain if intensified statins are tolerated and related to the preservation of cardiac function. We conducted a single-center, retrospective cohort study of all single-organ adult HT recipients between 2012 and 2021. Standard intensity statin was defined as pravastatin ≤20 mg or equivalent doses, while higher doses were defined as intensified statin. Overall, 277 patients met eligibility c