손재만 교수
Jaeman Son
서울대학교 · 물리·천문학
연구실 소개
손재만 교수의 연구실은 방사선 치료의 정밀도와 안전성을 높이기 위한 신뢰성 있는 실시간 모니터링 기술과 고성능 다이오드 센서 기반의 선량 측정 기술을 핵심으로 연구를 진행하고 있습니다. 특히 프로톤 치료에서의 입자비례 스캐닝( pencil beam scanning ) 방식의 품질보증(QA)을 위한 섬세한 비례 센서 기반의 실시간 빔 모니터링 시스템과 유연하고 저비용의 피부선량 측정 장치 개발에 주력하고 있습니다. 또한, 프로톤 치료에서의 선량 분포 정확성 확보를 위해 광섬유 기반 방사선 센서(FORS)의 선형성, 선량률 의존성 등 물리적 특성과 임상 적용 가능성을 체계적으로 평가하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15QA results and consistencies depend on the choice of dosimetric tool. Universal passing rates should depend on the normalization or inter-comparisons of dosimetric tools if more than one dosimetric tool is used for patient specific QA.
In TMI treatment, reducing the dose rate administered to the lung can decrease the incidence of pulmonary toxicity. To reduce the probability of normal tissue complications, the selection of the lowest MU rate is recommended for fields including the lung. To minimize the total treatment time, the maximum MU rate can be applied to other fields.
This study describes the development of a beam monitoring system for the verification of entrance dose map in pencil beam scanning (PBS) proton therapy based on fiber optic radiation sensors (FORS) and the validation of this system through a feasibility study. The beam monitoring system consisted of 128 optical fibers optically coupled to photo-multiplier tubes. The performance of the beam monitoring system based on FORS was verified by comparing 2D dose maps of square-shaped fields of various s
We present the construction of a flexible skin dosimeter based on a CIGS solar cell. Our findings demonstrate that the CIGS solar cell has a potential to be a novel flexible skin dosimeter for electron radiotherapy. Moreover, this dosimeter is manufactured with low cost and can be easily customized to various size/shape, which represents advantages over other dosimeters.
Abstract Purpose We investigated the properties of platinum-catalyzed silicones with suitable characteristics for a biocompatible patient-specific elastic bolus. Materials & Methods We applied a platinum-catalyzed silicone (Ecoflex™ 0030) and a platinum cure liquid silicone (Dragon Skin™ 10 MEDIUM) to fabricate a biocompatible bolus using a mold and casting method with a 3D printer. We conducted physical evaluations including the shore hardness, cure time, transparency, and mixed viscosity.
We aimed to develop a beam monitoring system based on a fiber-optic radiation sensor (FORS), which can be used in real time in a beam control room, to monitor a beam in proton therapy, where patients are treated using a pencil beam scanning (PBS) mode, by measuring the beam spot width (BSW) and beam spot position (BSP) of the PBS. We developed two-dimensional detector arrays to monitor the PBS beam in the beam control room. We measured the BSW for five energies of the PBS beam and compared the m
The aims of this study were to investigate the characteristics of a fiber-optic radiation sensor (FORS) that detects the fluorescence light produced by proton beam and to verify its effectiveness in proton therapy quality assurance (QA). Various characteristics of the FORS were investigated, such as the linearity of its relationships to the sensitive length of fiber for the proton beams of intermediate ranges (165.46 and 178.37 MeV) and to the measured dose, as well as its dose rate dependence.
Purpose: We investigated the properties of CLEANBOLUS based on silicone with suitable characteristics for clinical use.
Background: Stereotactic ablative radiotherapy (SABR) plans in prostate cancer are compared and analyzed to investigate the low magnetic effect (0.35 T) on the dose distribution, with various dosimetric parameters according to low magnetic field.
Several detectors have been developed to measure radiation doses during radiotherapy. However, most detectors are not flexible. Consequently, the airgaps between the patient surface and detector could reduce the measurement accuracy. Thus, this study proposes a dose measurement system based on a flexible copper indium gallium selenide (CIGS) solar cell. Our system comprises a customized CIGS solar cell (with a size 10 × 10 cm2 and thickness 0.33 mm), voltage amplifier, data acquisition module, a
To investigate the effect of low magnetic field on dose distribution in SABR plans for liver cancer, we calculated and evaluated the dose distribution to each organ with and without magnetic fields. Ten patients received a 50 Gy dose in five fractions using the ViewRay® treatment planning system. For planning target volume (PTV), the results were analyzed in the point minimum (Dmin), maximum (Dmax), mean dose (Dmean) and volume receiving at least 90% (V90%), 95% (V95%), and 100% (V100%) of the p
Purpose: The purpose of this work was to measure gold nanoparticles (AuNPs) induced dose enhancement physically in radiotherapy which has never been verified with experiment although some results in biological experiment indicates that AuNPs can cause the dose enhancement. Methods: Homemade phantom was specially designed to measure dose changes with/without AuNPs and a model GD-302m glass dosimeter (AGC Techno Glass Corp., Shizuoka, Japan) and FGD-1000 automatic reader were used to measure absor
Background: We investigated the impact of 0.35 T magnetic field on dose calculation for nonsmall cell lung cancer (NSCLC) stereotactic ablative radiotherapy (SABR) in the ViewRay system (ViewRay Inc.), which features a simultaneous use of magnetic resonance imaging (MRI) to guide radiotherapy for an improved targeting of tumors.Materials and Methods: Here, we present a comprehensive analysis of the effects induced by the 0.35 T magnetic field on various characteristics of SABR plans including th
The multilayer ADRS is well suited to verifying the energy of a pencil beam. The acrylic materials used in its configuration make this device easier to use and more cost-effective than conventional detectors. This device, with its high extensibility and stability, may be applicable as a new dosimetry tool for PBS.
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