채지원 교수
Jee Won Chai
서울대학교 · 의학
연구실 소개
채지원 교수의 연구실은 주로 관절 질환, 특히 퇄관절과 무릎의 퇄관염에서의 줄기세포 치료에 초점을 맞추고 있습니다. 자가 지방 tissue에서 유래한 간엽줄기세포(AD-MSCs)를 관절 내 주입하여 퇄관조직 재생을 유도하는 치료 전략을 개발하고 있으며, 이는 전임상적 및 임상적 연구를 통해 안전성과 유효성을 검증하고 있습니다. 특히 경추 척수경화의 영상 진단 평가 체계 개발을 통해 정밀한 진단 기반의 치료 접근도 함께 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Mesenchymal stem cells (MSCs) are known to have a potential for articular cartilage regeneration. However, most studies focused on focal cartilage defect through surgical implantation. For the treatment of generalized cartilage loss in osteoarthritis, an alternative delivery strategy would be more appropriate. The purpose of this study was to assess the safety and efficacy of intra-articular injection of autologous adipose tissue derived MSCs (AD-MSCs) for knee osteoarthritis. We enrolled 18 pat
Osteoid osteoma is characterized by an intracortical nidus with a variable amount of calcification, as well as cortical thickening, sclerosis, and bone marrow edema. When these findings are present, a diagnosis of osteoid osteoma is easily made. However, osteoid osteoma may display imaging findings that can be misleading, and it can be difficult to differentiate osteoid osteoma from other conditions such as infection, inflammatory and noninflammatory arthritis, and other tumors. In addition, str
NCT01300598.
The new grading system provides a reliable assessment of cervical canal stenosis.
Despite relatively good results of current symptomatic treatments for rotator cuff disease, there has been an unmet need for fundamental treatments to halt or reverse the progress of disease. The purpose of this study was to assess the safety and efficacy of intratendinous injection of autologous adipose tissue-derived mesenchymal stem cells (AD MSCs) in patients with rotator cuff disease. The first part of the study consists of three dose-escalation cohorts; the low- (1.0 × 10<sup>7</sup> cells
The new MRI grading system shows sufficient interobserver and intraobserver agreement to reliably assess cervical NFS.
MDCT provides a reliable method to evaluate the vascular anatomy and variations of living kidney donors.
Level III, retrospective comparative study.
Ultrasonography (US) is a useful diagnostic method that can be easily applied to identify the cause of shoulder pain. Its low cost, excellent diagnostic accuracy, and capability for dynamic evaluation are also advantages. To assess all possible causes of shoulder pain, it is better to follow a standardized protocol and to perform a comprehensive evaluation of the shoulder than to conduct a focused examination. Moreover, a proper dynamic study can enhance the diagnostic quality of US, especially
Objective: To determine the accuracy of the use of multi-detector row CT (MDCT) to predict vascular anatomy in living kidney donors and to reveal the prevalence of vascular variations in a Korean population. Materials and Methods: A total of 153 living kidney donors that had undergone preoperative CT and nephrectomy, either with open or laparoscopic surgery, were selected retrospectively. The initial CT results were compared with the surgical findings and repeated review sessions of CT scans wer
Measurement of vascular flow at the subcoracoid fat triangle using SMI facilitated the diagnosis of adhesive capsulitis. Superb Microvascular Imaging was superior to PDUS in diagnostic performance. Vascular flow was negatively correlated with the range of motion of external rotation and forward flexion.
T2 relaxation time measured with axial T2 mapping in degenerated discs is a potential method to assess disc degeneration.
Elbow snapping by annular ligament is rare and may be difficult to diagnose, when this Epub ahead of print condition is not familiar. We report a case of elbow snapping by annular ligament diagnosed by ultrasonography, which was confirmed by arthroscopic observation. The ultrasonographic findings were thickening of the annular ligament and snapping in and out of the radiocapitellar joint during elbow flexion and extension on dynamic ultrasonography.
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