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김지영 교수

Ji Young Kim

서울대학교 · 생화학·유전·분자생물학

연구실 소개

김지영 교수의 연구실은 신경퇴행성질환, 비만 및 대사질환의 분자 기전을 규명하고, 천연물질과 나노소재 기반의 혁신적 치료 전략을 개발하는 데 초점을 맞추고 있습니다. 알츠하이머병과 비만의 대사적 기전을 메타볼로믹스와 분자생물학적 기법을 통해 분석하며, 특히 카페올, 카페스톨과 같은 커피 유도체의 항염증 및 세포보호 효과에 대한 기전 연구도 진행하고 있습니다. 또한, 아연 기반 고성능 전지의 안정성 향상을 위한 나노구조 전극 설계와 전기화학적 특성 분석도 핵심 연구 분야입니다.

알츠하이머병메타볼로믹스천연물질나노전극비만 대사질환

연구 현황

논문 수
564
총 인용 수
12,276
최근 5년 논문
73
주요 분야
생화학·유전·분자생물학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
73총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
369총합
20222023202420252026

주요 논문

15
1
리뷰|인용수 680·2009
A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
Jiyoung Kim, Young‐Nam Cha, Young‐Joon Surh
SJR Q3FWCI 9.8Mutation research. Fundamental and molecular mechanisms of mutagenesis
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
리뷰|인용수 347·2009
Naturally occurring phytochemicals for the prevention of Alzheimer’s disease
Jiyoung Kim, Hyong Joo Lee, Ki Won Lee
SJR Q1FWCI 11.0Journal of NeurochemistryOA

Alzheimer's disease (AD) is an age-related neurodegenerative disease increasingly recognized as one of the most important medical problems affecting the elderly. Although a number of drugs, including several cholinesterase inhibitors and an NMDA receptor antagonist, have been approved for use, they have been shown to produce diverse side effects and yield relatively modest benefits. To overcome these limitations of current therapeutics for AD, extensive research and development are underway to i

PhysiologyMedicine
3
논문|인용수 177·2009
The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator
Jiyoung Kim, Jin‐Ki Kim, Jeong‐Sook Park, Youngro Byun, Chong‐Kook Kim
SJR Q1FWCI 4.6Biomaterials
BiomaterialsMaterials Science
4
논문|인용수 129·2012
Caffeinated coffee, decaffeinated coffee, and the phenolic phytochemical chlorogenic acid up-regulate NQO1 expression and prevent H2O2-induced apoptosis in primary cortical neurons
Jiyoung Kim, Siyoung Lee, Jaesung Shim, Hyo Won Kim, Jaekyoon Kim, Young Jin Jang, Hee Seok Yang, Ji‐Man Park, Seung Hwan Choi, Ji Hye Yoon, Ki Won Lee, Hyong Joo Lee
SJR Q2FWCI 8.9Neurochemistry International
PharmacologyMedicine
5
논문|인용수 128·2008
Transport routes and source regions of Asian dust observed in Korea during the past 40 years (1965–2004)
Jiyoung Kim
SJR Q1FWCI 6.1Atmospheric Environment
Global and Planetary ChangeEnvironmental Science
6
논문|인용수 127·2013
무용교육자의 비언어적 커뮤니케이션 능력, 지도자 신뢰 및 무용몰입의 구조적 관계
김지영, 주형철, 윤인애

그동안 무용교육자의 교수능력과 교수행위에 관한 논의가 많이 이루어져 온 것에비해, 교수자의 신체언어, 외향언어, 청각언어와 같은 비언어적 소통 능력(nonverbal communication)이 학습자의 태도에 영향을 미치는 중요한 교수행동 요소를 밝히는 연구들은 부족했다. 하지만 비언어적 커뮤니케이션이 학생들에게 수업에 대한 이해도와 몰입도를향상시킬 수 있기 때문에(이경탁, 2010, p.125), 효율적인 교수방법과 수업전략을 구사하기위해서는 비언어적 의사소통의 중요성이 강조된다. 따라서 이 연구의 기본 전제는 언어적커뮤니케이션과 비언어적 커뮤니케이션의 어느 한쪽에 비중을 두고 커뮤니케이션의 기능을논쟁하기 보다는, 전달하고자 하는 메시지의 송신과정에서 비언어적 요소들을 중점으로 논의를 하고자 한다. 또한 비언어적 커뮤니케이션을 활용할 때 메시지의 설명력이나 전달력이배가되어 소통을 더욱 극대화시킬 수 있다는 관점에서(이호열, 박재우, 2012 재인용, p.224;Birdwhiste

7
논문|인용수 120·2004
Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression
Jiyoung Kim
SJR Q1FWCI 3.0Pharmacological Research
ImmunologyImmunology and Microbiology
8
논문|인용수 103·2019
Estimation of ground-level particulate matter concentrations through the synergistic use of satellite observations and process-based models over South Korea
Seohui Park, Minso Shin, Jungho Im, Chang‐Keun Song, Myungje Choi, Jhoon Kim, Seungun Lee, Rokjin J. Park, Jiyoung Kim, Dong-Won Lee, Sang-Kyun Kim
SJR Q1FWCI 6.7Atmospheric chemistry and physicsOA

Abstract. Long-term exposure to particulate matter (PM) with aerodynamic diameters < 10 (PM10) and 2.5 µm (PM2.5) has negative effects on human health. Although station-based PM monitoring has been conducted around the world, it is still challenging to provide spatially continuous PM information for vast areas at high spatial resolution. Satellite-derived aerosol information such as aerosol optical depth (AOD) has been frequently used to investigate ground-level PM concentrations. In this stu

Health, Toxicology and MutagenesisEnvironmental Science
9
논문|인용수 101·2008
Multiple Myeloma-Related WHSC1/MMSET Isoform RE-IIBP Is a Histone Methyltransferase with Transcriptional Repression Activity
Jiyoung Kim, Hae Jin Kee, Nakwon Choe, Sung‐Mi Kim, Gwang-Hyeon Eom, Hee Jo Baek, Hyun Kook, Hoon Kook, Sang-Beom Seo
SJR Q2FWCI 3.6Molecular and Cellular BiologyOA

Histone methylation is crucial for transcriptional regulation and chromatin remodeling. It has been suggested that the SET domain containing protein RE-IIBP (interleukin-5 [IL-5] response element II binding protein) may perform a function in the carcinogenesis of certain tumor types, including myeloma. However, the pathogenic role of RE-IIBP in these diseases remains to be clearly elucidated. In this study, we have conducted an investigation into the relationship between the histone-methylating

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
논문|인용수 89·2004
Calcium-Mediated Activation of c-Jun NH2-Terminal Kinase (JNK) and Apoptosis in Response to Cadmium in Murine Macrophages
Jiyoung Kim
SJR Q1FWCI 4.6Toxicological SciencesOA

Cadmium is a well-known carcinogenic and immunotoxic metal commonly found in cigarette smoke and industrial effluent. An altered intracellular calcium ([Ca(2+)](i)) level has been implicated in the pathophysiology of immune dysfunction. The present study was designed to determine the possible involvement of calcium (Ca(2+)) and mitogen-activated protein kinases (MAPKs) signaling pathways on cadmium-induced cell death in J774A.1 murine macrophage cells. Cadmium caused a low-amplitude [Ca(2+)](i)

Health, Toxicology and MutagenesisEnvironmental Science
11
리뷰|인용수 89·2013
Cocoa Phytochemicals: Recent Advances in Molecular Mechanisms on Health
Jiyoung Kim, Jaekyoon Kim, Jaesung Shim, Chang Yong Lee, Ki Won Lee, Hyong Joo Lee
SJR Q1FWCI 3.2Critical Reviews in Food Science and Nutrition

Recent reports on cocoa are appealing in that a food commonly consumed for pure pleasure might also bring tangible benefits for human health. Cocoa consumption is correlated with reduced health risks of cardiovascular diseases, hypertension, atherosclerosis, and cancer, and the health-promoting effects of cocoa are mediated by cocoa-driven phytochemicals. Cocoa is rich in procyanidins, theobromine, (-)-epicatechin, catechins, and caffeine. Among the phytochemicals present in consumed cocoa, theo

BiochemistryMedicine
12
논문|인용수 80·2014
Sulforaphane alleviates scopolamine-induced memory impairment in mice
Siyoung Lee, Jisung Kim, Jisung Kim, Sang Gwon Seo, Bo‐Ryoung Choi, Jung‐Soo Han, Ki Won Lee, Jiyoung Kim, Jiyoung Kim
SJR Q1FWCI 3.7Pharmacological Research
Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
논문|인용수 80·2006
Influences of relative humidity on aerosol optical properties and aerosol radiative forcing during ACE-Asia
Soon‐Chang Yoon, Jiyoung Kim
SJR Q1FWCI 1.7Atmospheric Environment
Global and Planetary ChangeEnvironmental Science
14
논문|인용수 78·2007
<i>Ex Vivo</i> Characteristics of Human Amniotic Membrane-Derived Stem Cells
Jiyoung Kim, Hyun Mi Kang, Haekwon Kim, Mee‐Ran Kim, Hyuck Chan Kwon, Myung Chan Gye, Sung Goo Kang, Hong Yang, Juice You
FWCI 1.8Cloning and Stem Cells

Cells were isolated from four human amniotic membranes, and their biological characteristics analyzed during ex vivo expansion. Morphologically homogenous populations of fibroblast-like cells were obtained from the second or third passage. Under the appropriate culture conditions, these human amniotic membrane-derived mesenchymal cells (HAM) were shown to differentiate into adipocytes, osteocytes, chondrocytes and neuronal cells, as visualized by Oil Red O, von Kossa, alcian blue, anti-Neu N, an

GeneticsMedicine
15
논문|인용수 76·2016
Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways
Jisung Kim, Jisung Kim, Siyoung Lee, Bo‐Ryoung Choi, Hee Seok Yang, Youjin Hwang, Jung Han Yoon Park, Frank M. LaFerla, Jung‐Soo Han, Ki Won Lee, Jiyoung Kim, Jiyoung Kim
SJR Q1FWCI 3.3Molecular Nutrition & Food Research

These findings suggest that sulforaphane has the potential to prevent neuronal disorders such as Alzheimer's disease by epigenetically enhancing neuronal BDNF expression and its TrkB signaling pathways.

Molecular BiologyBiochemistry, Genetics and Molecular Biology

대표 연구 분야

Molecular BiologyPharmacologyHealth, Toxicology and MutagenesisImmunologyGlobal and Planetary ChangeBiochemistry

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