문진수 교수
Jin Soo Moon
서울대학교 · 의학
연구실 소개
문진수 교수의 연구실은 아동의 신체발달과 성장 평가를 중심으로, 체질량지수, 키, 체중 등 인체측정 자료를 바탕으로 한 성장기 건강 문제를 종합적으로 분석합니다. 특히 비만과 관련된 대사 변화, 만성 염증 반응, 그리고 장내면역 조절 메커니즘을 규명하는 데 초점을 맞추고 있으며, 소아 염증성 장질환의 발달 기전과 치료 전략 개발에도 기여하고 있습니다. 최근에는 대사체학적 분석을 통해 비만 청소년의 병태생리적 특징을 규명하는 데에도 성공적으로 응용하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers for Disease Control (CDC) have been changed their principles of growth charts to c
Significantly different metabolome signatures were identified between normal-weight and obese adolescents. Combined untargeted and targeted metabolomics demonstrated that inflammation-driven insulin resistance, ammonia toxicity and oxidative stress may represent crucial metabolomic signatures in obese adolescents.
N ational health screening program for infants and children in Korea was launched in November 2007 to cope with current health issues, such as high prevalence of accidents and incremental trends of developmental disorders and obesity. It is a kind of population surveillance systems which contains history taking, physical examination, anthropometric measurements, screening for visual acuity and questionnaires with anticipatory guidance. This program has been successfully implanted as one of the p
An anthropometric survey is one of the most important approaches to use when evaluating the health status of children. Secular trends in body sizes, such as height, weight, head circumference, chest circumference, and body mass index showed significant changes over 40 years in Korea. A series of periodic surveys were conducted in 1967, 1975, 1985, 1997, and 2005 by the Korean Pediatric Society and Ministry of Health and Welfare. The quality of data from school health examinations and the Korea N
The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide, especially in the developing countries. It differs from adult disease in clinical manifestations, especially with regard to genetic predisposition in monogenic IBD. Pediatric disease also have a tendency to show more aggressive inflammation and greater extent of lesion. Newer drugs such as anti-tumor necrosis factor α have been known to make a difference in treating pediatric IBD. Recent studies suggested that t
The NCR<sup>-</sup> ILC3: GM-CSF: neutrophil axis could contribute to the development of IBD.
This study aimed at developing an artificial-neural-network (ANN)-based model that can calculate the required time for restoring the current indoor temperature during the setback period in accommodation buildings to the normal set-point temperature in the cooling season. By applying the calculated time in the control logic, the operation of the cooling system can be predetermined to condition the indoor temperature comfortably in a more energy-efficient manner. Three major steps employing the nu
This study was conducted to develop an artificial neural network (ANN)-based prediction model that can calculate the amount of cooling energy during the setback period of accommodation buildings. By comparing the amount of energy needed for diverse setback temperatures, the most energy-efficient optimal setback temperature could be found and applied in the thermal control logic. Three major processes that used the numerical simulation method were conducted for the development and optimization of
We report the fabrication, characterization, and field emission properties of (silicon oxide) SiOx coated thin-multiwalled carbon nanotubes (t-MWNTs). The coated t-MWNTs show improved field emission behavior. Initially, raw t-MWNTs (diameter ∼5–8nm) were functionalized by acid treatment. Using spin on glass as a Si precursor, SiOx was coated on the nanotubes by routine chemical methods. The coated samples were characterized by high resolution transmission electron microscopy (HRTEM), Fourier tra
A prognostic scoring system using the change of TB/INR may be useful for predicting mortality in patients with PALF.
Purpose:Results of the Korea National Health Screening Program for Infants and Children, which was launched in November 2007, were evaluated for future research and policy development. Methods:Data from a total of 2,729,340 cases were analyzed. Five visiting ages, such as 4, 9, 18, 30, and 60 months, were included. Several parameters such as stunting, obesity, and positive rate of developmental screening were also analyzed. Telephone survey was performed in 1,035 users. For the provider survey,
The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide, especially in the developing countries. It differs from adult disease in clinical manifestations, especially with regard to genetic predisposition in monogenic IBD. Pediatric disease also have a tendency to show more aggressive inflammation and greater extent of lesion. Newer drugs such as antitumor necrosis factor α have been known to make a difference in treating pediatric IBD. Recent studies suggested that th
목 적: 보건복지부 및 국민건강보험공단에 의해 국내 최초로 영유아 건강검진 사업이 2007년 11월에 시작되었다. 본 연구진은 이 사업에서 포함되는 영양상담 프로그램을 개발하였다. 방 법: 연구진은 대한소아과학회에서 발행되는 영양지침 관련 자료와 미국의 Bright Future, 세계보건기구의 지침들을 참고하였다. 또한, 국내의 중요한 영양 관련 역학 연구인 국민건강영양조사 자료 및 2005년 소아청소년 신체발육표준치 결과를 분석하였다. 문진표와 보호자용 설명서, 컴퓨터 프로그램 및 의사용 지침서를 만들기 위해 연구자들과 정책 담당자들 간의 수차례 회의를 거쳤다. 결 과: 다수의 학문적이고 역학적인 근거를 통해 연령별 영양상담 핵심 주제를 선정하였다. 이는 영유아에서의 모유수유, 보다 건강한 보충식, 철 결핍빈혈의 예방, 보다 건강한 소아 식이, 과체중을 예방하기 위한 영양상담, 그리고 신체활동의 강조 등이다. 이에 근거하여 4개월, 9개월, 18개월, 30개월, 그리고 만 5세의
This study examines the performance and adaptability of Artificial Neural Network (ANN)-based thermal control strategies for diverse thermal properties of building envelope conditions applied to residential buildings. The thermal performance using two non-ANN-based control logics and two predictive ANN-based control logics was numerically tested using simulation software after validation. The performance tests were conducted for a two-story single-family house for various envelope insulation lev
This study aims at developing an indoor temperature control method that could provide comfortable thermal conditions by integrating heating system control and the opening conditions of building envelopes. Artificial neural network (ANN)-based temperature control logic was developed for the control of heating systems and openings at the building envelopes in a predictive and adaptive manner. Numerical comparative performance tests for the ANN-based temperature control logic and conventional non-A
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