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이종호 (S) 교수

Jong Ho Lee

서울대학교 · 의학

연구실 소개

이종호 교수 연구실은 대사질환 예방과 건강 기능 개선을 목표로 한 프로바이오틱스, 천연 보조제 및 생체활성 물질의 임상적 효과를 중심으로 연구를 진행하고 있습니다. 특히 당뇨 전단계 및 제2형 당뇨병 환자를 대상으로 한 프로바이오틱스, 한국홍삼, 케이소산 올리고사카라이드 등의 보조제가 혈액 중 혈액순환 및 면역 기능에 미치는 영향을 다각도로 분석하고 있습니다. 또한 항산화 작용과 알코올 대사 개선 효과를 비롯해 체지방 감소 및 대사 중개물질 변화에 대한 기전 연구도 함께 수행하고 있습니다.

프로바이오틱스당뇨 전단계홍삼혈액 대사체지방 감소

연구 현황

논문 수
400
총 인용 수
8,909
최근 5년 논문
40
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
40총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
404총합
20212022202320242025

주요 논문

15
1
논문|인용수 122·2011
Effects of aging and menopause on serum interleukin-6 levels and peripheral blood mononuclear cell cytokine production in healthy nonobese women
Oh Yoen Kim, Jey Sook Chae, Jean Kyung Paik, Hee Sun Seo, Yangsoo Jang, Jean-Marc Cavaillon, Jong Ho Lee
FWCI 3.2AGEOA
EpidemiologyMedicine
2
논문|인용수 109·2017
Consumption of Dairy Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune Function Including Natural Killer Cell Activity
Ayoung Lee, Young Ju Lee, Hye Jin Yoo, Min-Kyung Kim, Yeeun Chang, Dong Seog Lee, Jong Ho Lee
SJR Q1FWCI 10.6NutrientsOA

The aim of this study was to investigate the impact of consuming dairy yogurt containing <i>Lactobacillus paracasei</i> ssp. <i>paracasei</i> (<i>L. paracasei</i>), <i>Bifidobacterium animalis</i> ssp. <i>lactis</i> (<i>B. lactis</i>) and heat-treated <i>Lactobacillus plantarum</i> (<i>L. plantarum</i>) on immune function. A randomized, open-label, placebo-controlled study was conducted on 200 nondiabetic subjects. Over a twelve-week period, the test group consumed dairy yogurt containing probio

Food ScienceAgricultural and Biological Sciences
3
논문|인용수 104·2007
Association of the Gly82Ser polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating levels of soluble RAGE and inflammatory markers in nondiabetic and nonobese Koreans
Yangsoo Jang, Ji Young Kim, Seok‐Min Kang, Jung‐Sun Kim, Jey Sook Chae, Oh Yoen Kim, Soo Jeong Koh, Hyun Chul Lee, Chul Woo Ahn, Young Duk Song, Jong Ho Lee
SJR Q1FWCI 4.7MetabolismOA
Clinical BiochemistryBiochemistry, Genetics and Molecular Biology
4
논문|인용수 92·2003
The preparation of TiO2 nanometer photocatalyst film by a hydrothermal method and its sterilization performance for Giardia lamblia
Jong Ho Lee, Misook Kang, Suk-Jin Choung, Kenji Ogino, Seizo Miyata, Moon-Sun Kim, Jong-Yul Park, Jin‐Bae Kim
SJR Q1FWCI 4.0Water Research
Renewable Energy, Sustainability and the EnvironmentEnergy
5
논문|인용수 83·2014
Korean Red Ginseng Improves Glucose Control in Subjects with Impaired Fasting Glucose, Impaired Glucose Tolerance, or Newly Diagnosed Type 2 Diabetes Mellitus
Hyangju Bang, Jung Hyun Kwak, Hyeon Yeong Ahn, Dong Yeob Shin, Jong Ho Lee
SJR Q3FWCI 2.3Journal of Medicinal FoodOA

This study was designed to evaluate the effect of Korean red ginseng (KRG) supplementation on glucose control in subjects with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or newly diagnosed type 2 diabetes mellitus (T2DM). The study was a 12-week randomized, double-blinded, placebo-controlled (5 g of KRG [n=21] or placebo [n=20] in tablet form) trial. Glucose-related biomarkers, including serum and whole blood levels of glucose, insulin, and C-peptide, were measured by 2-h

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 81·2005
Association of the 276G→T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans
Yangsoo Jang, Jong Ho Lee, Jong Ho Lee, Jey Sook Chae, Oh Yoen Kim, Soo Jeong Koh, Ji Young Kim, Hongkeun Cho, Jong Eun Lee, Jong Eun Lee, José M. Ordovás
SJR Q1FWCI 3.0American Journal of Clinical NutritionOA
EpidemiologyMedicine
7
논문|인용수 72·2012
Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial
Ji Young Kim, Ju Yeon Park, Hee-Jeong Kang, Oh Yoen Kim, Jong Ho Lee
SJR Q1FWCI 2.7Nutrition JournalOA

KRG supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 72·2014
The effects of chitosan oligosaccharide (GO2KA1) supplementation on glucose control in subjects with prediabetes
Hee Jun Kim, Hyeon Yeong Ahn, Jung Hyun Kwak, Dong Yeob Shin, Young‐In Kwon, Chen-Gum Oh, Jong Ho Lee
SJR Q1FWCI 2.1Food & FunctionOA

We aimed to evaluate the effect of chitosan oligosaccharide (GO2KA1) supplementation on glucose control in subjects with prediabetes. This study was a randomized, double-blind, placebo-controlled clinical trial. Subjects with prediabetes were randomly assigned to the GO2KA1 intervention group or the placebo group for 12 weeks. We assessed the serum levels of glucose, insulin, and C-peptide by a 2 hour value in the 75 g oral glucose tolerance test (OGTT), HbA1c, pro-inflammatory cytokines, and pl

EpidemiologyMedicine
9
논문|인용수 72·2010
FADS gene polymorphisms in Koreans: Association with ω6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease
Jung Hyun Kwak, Jean Kyung Paik, Oh Yoen Kim, Yangsoo Jang, Sang‐Hak Lee, José M. Ordovás, Jong Ho Lee
SJR Q1FWCI 5.5AtherosclerosisOA
Nutrition and DieteticsNursing
10
논문|인용수 70·2009
Independent inverse relationship between serum lycopene concentration and arterial stiffness
Oh Yoen Kim, Hyun Yang Yoe, Hyae Jin Kim, Ju Yeon Park, Ji Young Kim, Sang‐Hak Lee, Jin Hee Lee, Kang Pyo Lee, Yangsoo Jang, Jong Ho Lee
SJR Q1FWCI 2.5AtherosclerosisOA
BiochemistryMedicine
11
논문|인용수 65·2012
Increased oxidative stress in normal-weight postmenopausal women with metabolic syndrome compared with metabolically healthy overweight/obese individuals
Minjoo Kim, Jean Kyung Paik, Ryungwoo Kang, Soo Young Kim, Sang‐Hyun Lee, Jong Ho Lee
SJR Q1FWCI 3.5Metabolism
BiochemistryMedicine
12
논문|인용수 65·2013
Red ginseng relieves the effects of alcohol consumption and hangover symptoms in healthy men: a randomized crossover study
Mi Hyang Lee, Jung Hyun Kwak, Gayoung Jeon, Jong Won Lee, Jong Won Lee, Jang-Ho Seo, Hoon-Sang Lee, Jong Ho Lee, Jong Ho Lee
SJR Q1FWCI 0.4Food & Function

Heavy drinking causes hangover symptoms, because the action of alcohol dehydrogenase forms acetaldehyde, which is metabolized by acetaldehyde dehydrogenase into acetate. Red ginseng shows positive effects on alcohol metabolism in animal studies. We investigated the effects of red ginseng on relieving alcohol and hangover symptoms in 25 healthy men in a randomized crossover study. At each visit (0, 1, and 2 weeks), the subjects drank 100 mL whiskey (40% alcohol) and either 100 mL water or 100 mL

Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
논문|인용수 64·2015
Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduces fasting triglycerides and enhances apolipoprotein A-V levels in non-diabetic subjects with hypertriglyceridemia
Hyeon Yeong Ahn, Minjoo Kim, Jey Sook Chae, Young-Tae Ahn, Jae-Hun Sim, Il-Dong Choi, Sang‐Hyun Lee, Jong Ho Lee
SJR Q1FWCI 7.2Atherosclerosis
Food ScienceAgricultural and Biological Sciences
14
논문|인용수 62·2016
Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals
Minkyung Kim, Minjoo Kim, Miso Kang, Hye Jin Yoo, Min Sun Kim, Young-Tae Ahn, Jae-Hun Sim, Sun Ha Jee, Jong Ho Lee
SJR Q1FWCI 2.3Food & FunctionOA

Our previous study showed that supplementation with a combination of Lactobacillus curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 reduced the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area in overweight subjects. We aimed to evaluate whether the changes in adiposity after supplementation with Lactobacillus strains were associated with metabolic intermediates. A randomized, double-blind, placebo-controlled study was conducted on 66 no

PhysiologyMedicine
15
논문|인용수 62·2013
Mild weight loss reduces inflammatory cytokines, leukocyte count, and oxidative stress in overweight and moderately obese participants treated for 3 years with dietary modification
Jey Sook Chae, Jean Kyung Paik, Ryungwoo Kang, Minjoo Kim, Yongin Choi, Sang‐Hyun Lee, Jong Ho Lee
SJR Q1FWCI 3.9Nutrition Research
PhysiologyMedicine

대표 연구 분야

Nutrition and DieteticsEpidemiologyMolecular BiologyCardiology and Cardiovascular MedicineMarketingSurgery

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