한종우 교수
Jong Woo Hahn
서울대학교 · 의학
연구실 소개
한종우 교수의 연구실은 소화기질환, 특히 비만성장운동장애(_CIPO_)와 에스칼라시아 등 희귀 소화기질환의 유전적 기전을 중심으로 연구를 진행하고 있습니다. 특히 한국 환자 집단에서 발견되는 <i>ACTG2</i> 유전자 변이의 역할을 규명하고, 임상적 진단 및 유전적 분석의 중요성을 제고하고 있습니다. 또한 전 세계적인 간질환 관련 사망률 증가 추세에 대비해, 간질환의 전 세계적 유행병학적 패턴과 정책적 대응 방안을 모색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15National Research Foundation of Korea.
PROSPERO (registration no. CRD42024527805).
The incidence and prevalence of achalasia have notably increased, particularly with advancements in diagnosis, and show significant variation worldwide, despite the large heterogeneity within the sample population. Further studies are necessary to accurately assess the global incidence and prevalence of achalasia.
Global age-standardized liver disease-related mortality has increased significantly and continues to emerge as a crucial global public health issue. Further investigation into liver disease-related mortality rates in Africa is needed, and updating policies is necessary to effectively manage the global burden of liver disease.
Abstract Additives used in tobacco product manufacturing are currently in the focus of public discussions with regard to potentially increased consumer health risks on account of certain additives. In addition, a few additives are suspected to enhance the addictiveness of tobacco products. In 2006, the German Federal Ministry for Food, Agriculture and Consumer Protection (BundesministeriumfuerErnaehrung, Landwirtschaft und Verbraucherschutz, BMELV) commissioned a research project intended to pro
Patients with pediatric-onset IBD exhibited a much shorter disease duration than that of adult-onset IBD at the time of diagnosis of CRC, suggesting that surveillance endoscopy for the detection of precancerous lesions and early-stage cancer should be initiated earlier in pediatric patients than in adult patients.
The diagnostic criteria of Rome IV are stricter than those of Rome III, which likely affects the estimated prevalence of FAPD and its subtypes.
Lifestyle modifications are fundamental in managing metabolic dysfunction-associated steatotic liver disease (MASLD). This study aimed to evaluate the effects of a 12-week lifestyle intervention on hepatic steatosis, liver function, and gut microbiota composition in pediatric MASLD patients, and to explore clinical and baseline microbial features associated with treatment response. A total of 40 patients were recruited, and 31 were included after applying exclusion criteria. After 12 weeks, sign
Supplementary Material 1.
Introduction: The incidence and severity of Clostridioides difficile infection (CDI) have been increasing over the past decades. It particularly contributes to acute exacerbations and worsen the severity of inflammatory bowel disease (IBD). Fecal microbiota transplantation (FMT) is one of standard treatments for recurrent CDI. The aim of this study was to evaluate the clinical outcome of FMT for recurrent CDI in pediatric patients with refractory IBD. Methods: From May 2013 through April 2023, w
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