이준우 교수
Joon Woo Lee
서울대학교 · 의학
연구실 소개
이준우 교수의 연구실은 주로 전자기파 영역, 특히 테라헤르츠 영역에서의 물질과 구조의 상호작용을 연구하며, 특히 정렬되지 않은 구멍 또는 슬릿 배열에서 나타나는 테라헤르츠 투과 현상에 초점을 맞추고 있습니다. 또한 의료 영상 진단, 특히 간내방사선영상(CT) 및 자기공명영상(MRI)을 활용한 암 및 혈관성 병변의 영상 특성 분석에도 활발히 기여하고 있습니다. 특히 간내방선암, BALT 림프종, 척추 Epidural Hemangioma 등의 영상 소견을 정밀하게 규명함으로써 임상 진단의 정확성을 높이는 데 기여하고 있습니다. 이는 기초 물리학적 현상과 임상의학의 융합적 연구를 지향하는 특징을 지닙니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15We report on the observation of terahertz transparency in random arrays of the single rectangular holes and slits with the areal coverage of only 12%. The terahertz transparency occurs at the fundamental shape resonance of the rectangular holes and confirms the theoretical predictions of earlier works of García-Vidal et al. [Phys. Rev. Lett. 95, 103901 (2005)] on single rectangular holes and of Ruan and Qiu [Phys. Rev. Lett. 96, 233901 (2006)] on random arrays of holes.
Our study suggests that, when considering tolerability, efficacy and patient satisfaction, low-dose treatment is most suitable for patients with moderate acne.
Segmental or lobar dilatation of the intrahepatic bile ducts associated with or without intraductal polypoid mass, amorphous structures, or both with slight hyperattenuation are common CT findings of intraductal intrahepatic cholangiocarcinoma. The size of the intraductal mass determines the visibility on CT.
BALT lymphomas usually appear as airspace consolidation or nodules with air bronchogram or adjacent ground-glass attenuation at CT. These findings are similar to previous descriptions of pseudolymphomas. Multiple bilateral lesions are common in BALT lymphoma. Bubble-like radiolucencies have not been described previously and can be an additional finding of BALT lymphoma.
We conclude that preganglionic TFESI has the better therapeutic effect on radiculopathy caused by nerve root compression at the level of the supra-adjacent disc than does conventional TFESI, and the difference between the two treatments had borderline statistical significance.
Spinal epidural hemangiomas can have various MR imaging features according to their different histopathologic backgrounds. In addition to common features such as solid hypervascularity, lobular contour, and a rim of low T2 signal intensity, T1 hyperintensity or multisegmental involvement may also be a clue in the differential diagnosis of a spinal epidural hemangioma.
Transforaminal epidural steroid is an effective tool for managing sciatica, and an extraepineural injection may be a predictor of a better outcome for sciatica treated using transforaminal epidural steroid.
Using terahertz time-domain spectroscopy, we study transmission in one-dimensional arrays of slits fabricated on metal plates by laser machining. The enhanced peaks of zero-order transmission spectra are attributed to the combined effects of Fabry–Perot and surface plasmon resonances. Angle dependence of transmission spectra shows that the strongly surface plasmon-enhanced peaks appear when the Fabry–Perot-type resonance is located nearby in energy. This means that surface waves traveling in the
We report on a perfect transmission in one-dimensional metallic structure using time-domain terahertz spectroscopy. Fabry-Perot resonance appearing in spectral region below first Rayleigh minimum strongly enhances transmission up to over ninety-nine percent. Theoretical calculations reveal that under the perfect transmission condition, a symmetric eigenmode inside the slits is excited and a funneling of all incident energy onto the slits occurs, resulting in large energy concentration equivalent
Optimal parameters for DTI in the cervical spinal cord included a b-value of 900 seconds/mm, 15 diffusion gradient directions, 5 excitations, and a slice thickness of 4mm.
FA values in lesions and in distal normal-appearing spinal cord significantly decreased in patients with idiopathic ATM, and FA decrease in distal normal-appearing spinal cord might be related to clinical outcome.
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