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이정찬 교수

Jung Chan Lee

서울대학교 · 의학

연구실 소개

이 교수의 연구실은 생물처리 기반의 환경 정화 기술과 의료용 약물 전달 시스템의 혁신을 동시에 추구하고 있습니다. 특히 매립막 생물반응기(MBR)를 활용한 오염물질 제거 기술과 약물의 고정 및 분포 제어를 위한 신소재 및 장치 개발에 초점을 맞추고 있으며, 임상 현장에서의 실용성과 정밀도를 높이기 위한 기기 및 분석 기법 개발도 함께 진행하고 있습니다. 특히 약물 분포의 균일성 향상과 생체 내 약물 동태 분석, 스마트폰 기반 진단 기술까지 연구 범위를 확장하고 있습니다.

생물반응기약물 분포압력 분사화학요법의료 기기 개발스마트폰 진단

연구 현황

논문 수
165
총 인용 수
2,177
최근 5년 논문
32
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
32총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
123총합
20222023202420252026

주요 논문

15
1
논문|인용수 101·2001
Potential and limitations of alum or zeolite addition to improve the performance of a submerged membrane bioreactor
Jung Chan Lee, J. S. Kim, In Jeong Kang, Myung‐Haing Cho, P. K. Park, Changhee Lee
SJR Q2FWCI 4.3Water Science & Technology

In this study, alum and natural zeolite were added to a submerged membrane bioreactor (MBR) not only to reduce membrane fouling but also to increase the removal of nitrogen and phosphorus. Alum addition reduced significantly the rising rate of suction pressure and also resulted in stable and better COD removal. Although phosphorus removal was more than 90% by chemical precipitation, nitrification inhibition was observed. With the addition of natural zeolite, membrane permeability was greatly enh

Water Science and TechnologyEnvironmental Science
2
논문|인용수 83·2007
Repair of Damaged Mold Surface by Cold-Spray Method
Jung Chan Lee, Hye-In Kang, W.S. Chu, Sung‐Hoon Ahn
SJR Q1FWCI 36.7CIRP Annals
Aerospace EngineeringEngineering
3
논문|인용수 41·2016
Investigation of Key Circuit Constituents Affecting Drug Sequestration During Extracorporeal Membrane Oxygenation Treatment
Jiheum Park, Dong Ah Shin, Saram Lee, Young‐Jae Cho, Sanghoon Jheon, Jung Chan Lee, Hee Chan Kim
SJR Q1FWCI 2.6ASAIO Journal

We quantified the influence of the elements of the extracorporeal oxygenation (ECMO) circuit on drug sequestration by focusing on the interactions between materials and drugs. Tubing of three different brands (Tygon/Maquet/Terumo) and oxygenators of two different brands (Maquet/Terumo) were used. Drugs included dexmedetomidine, meropenem, and heparin, which were dissolved in deionized water. Tubing was cut into approximately 7 cm sections and allowed drug solutions enclosed inside by clamping bo

Critical Care and Intensive Care MedicineMedicine
4
논문|인용수 25·2016
Real-time tidal volume feedback guides optimal ventilation during simulated CPR
Kyoung Min You, Chiwon Lee, Woon Yong Kwon, Jung Chan Lee, Gil Joon Suh, Kyung Su Kim, Min Ji Park, Sungwan Kim
SJR Q1FWCI 1.5The American Journal of Emergency Medicine
Emergency MedicineMedicine
5
논문|인용수 25·2021
Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum
Soo Jin Park, Eun Ji Lee, Hee Su Lee, Jun‐Sik Kim, Sung Soo Park, Jiyeon Ham, Jaehee Mun, Haerin Paik, Hyunji Lim, Aeran Seol, Ga Won Yim, Seung‐Hyuk Shim
SJR Q1FWCI 2.9Drug DeliveryOA

This study aims to evaluate the drug distribution, tissue concentrations, penetration depth, pharmacokinetic properties, and toxicities after rotational intraperitoneal pressurized aerosol chemotherapy (RIPAC) in pigs. Because relevant medical devices have not been introduced, we developed our prototype of pressurized intraperitoneal aerosol chemotherapy (PIPAC) and RIPAC by adding a conical pendulum motion device for rotating the nozzle. RIPAC and PIPAC were conducted using 150 ml of 1% methyle

SurgeryMedicine
6
논문|인용수 18·2020
Evaluation of a Novel Prototype for Pressurized Intraperitoneal Aerosol Chemotherapy
Hee Su Lee, Jun‐Sik Kim, Eun Ji Lee, Soo Jin Park, Jaehee Mun, Haerin Paik, Soo Hyun Oh, Sung Soo Park, Soomin Ryu, Whasun Lim, Gwonhwa Song, Hee Seung Kim
SJR Q1FWCI 2.2CancersOA

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been suggested as an alternative option for treating peritoneal carcinomatosis (PC). Even with its clinical advantages, the current PIPAC system still suffers from limitations regarding drug distribution area and penetration depth. Thus, we evaluated the new PIPAC system using a novel prototype, and compared its performance to the results from previous studies related with the current MIP<sup>®</sup> indirectly because the system is cu

SurgeryMedicine
7
논문|인용수 16·2012
Mathematical analysis for internal filtration of convection-enhanced high-flux hemodialyzer
Jung Chan Lee, Kyungsoo Lee, Hee Chan Kim
SJR Q1FWCI 0.7Computer Methods and Programs in Biomedicine
NephrologyMedicine
8
논문|인용수 16·2016
Smartphone-Based Urine Reagent Strip Test in the Emergency Department
Karam Choi, Ikwan Chang, Jung Chan Lee, Do Kyun Kim, Seungwoo Noh, Heejeong Ahn, Jun Hwi Cho, Young Ho Kwak, Sungwan Kim, Hee Chan Kim
SJR Q1FWCI 1.2Telemedicine Journal and e-Health

Our results demonstrated the clinical capability of a smartphone-based urine reagent strip test, and this reader is expected to enable a more rapid and reliable colorimetric test for screening of LE and NIT at the clinical setting and the point of care.

Biomedical EngineeringEngineering
9
논문|인용수 14·2017
Application of genetic algorithm for hemodialysis schedule optimization
Jin Woo Choi, Hajeong Lee, Jung Chan Lee, Saram Lee, Yon Su Kim, Hyung‐Jin Yoon, Hee Chan Kim
SJR Q1FWCI 1.2Computer Methods and Programs in Biomedicine
NephrologyMedicine
10
논문|인용수 14·2016
Computer-assisted detection of swallowing difficulty
Jung Chan Lee, Han Gil Seo, Woo Hyung Lee, Hee Chan Kim, Tai Ryoon Han, Byung‐Mo Oh
SJR Q1FWCI 2.4Computer Methods and Programs in Biomedicine
Speech and HearingHealth Professions
11
논문|인용수 10·2013
글쓰기 교육을 위한 과학 텍스트 분석 연구
이정찬
우리말교육현장연구

본 연구는 ‘과학 글쓰기’에 대한 기존의 개념을 비판적으로 점검하고, 아울러 과학 텍스트의 특징을 고찰함으로써 대학교 교양 교육으로서의 ‘과학 글쓰기’에 적합한 교육 내용을 제안하고자 한다. 과학 글쓰기란 ‘과학계에서 사용하는 지배적인 논증 방식을 통해 실험 혹은 연구의 과정을 객관화하고 거기서 얻어낸 자료를 통해 결론을 일반화하는 일련의 논증 텍스트를 산출’하는 것이라 할 수 있다. 이는 개념화를 통한 논리의 구축, 수치화 및 추론을 통한 인과성의 강조, 귀납적 방법론에 기초한 배열 방식, 문법적 은유와 피동형 문장의 사용 등 과학계에서 사용하는 지배적인 논증의 방식과 그 논증 방식에 적합한 언어적 형식으로 특징지을 수 있다. 따라서 과학 글쓰기 교육이란 단순히 텍스트의 형식만을 대상으로 하는 것이 아닌 학습자로 하여금 과학적 논증의 방식에 대한 이해, 그러한 논증의 방식을 적용하거나 활용해서 타당한 결론을 도출하도록 하는 논증 과정에 대한 이해, 이러한 논증의 방식을 효과적으로

12
논문|인용수 9·2019
Effect of endotracheal intubation and supraglottic airway device placement during cardiopulmonary resuscitation on carotid blood flow over resuscitation time: An experimental porcine cardiac arrest study
Tae Han Kim, Ki Jeong Hong, Sang Do Shin, Jung Chan Lee, Dong Sun Choi, Ikwan Chang, Yoo Ha Joo, Young Sun Ro, Kyoung Jun Song
SJR Q1FWCI 1.8Resuscitation
Emergency MedicineMedicine
13
논문|인용수 8·2010
NOTES ON CRITICAL ALMOST HERMITIAN STRUCTURES
Jung Chan Lee, JeongHyeong Park, Kouei Sekigawa
SJR Q3FWCI 2.5Bulletin of the Korean Mathematical SocietyOA

We discuss the critical points of the functional <TEX>$F_{\lambda,\mu}(J,g)=\int_M(\lambda\tau+\mu\tau^*)d\upsilon_g$</TEX> on the spaces of all almost Hermitian structures AH(M) with <TEX>$(\lambda,\mu){\in}R^2-(0,0)$</TEX>, where <TEX>$\tau$</TEX> and <TEX>$\tau^*$</TEX> being the scalar curvature and the *-scalar curvature of (J, g), respectively. We shall give several characterizations of Kahler structure for some special classes of almost Hermitian manifolds, in terms of the critical points

Applied MathematicsMathematics
14
논문|인용수 8·2011
In Silico Evaluation of Glucose Control Protocols for Critically Ill Patients
Jung Chan Lee, Myeungseon Kim, Ka Ram Choi, Tae Jung Oh, Min Young Kim, Young Min Cho, Kyuseok Kim, Hee Chan Kim, Sungwan Kim
SJR Q1FWCI 1.0IEEE Transactions on Biomedical Engineering

This letter presents an in silico evaluation method of glucose control protocols for critically ill patients with hyperglycemia. Although various glucose control protocols were introduced and investigated in clinical trials, development and validation of a novel glucose control protocol for critically ill patients require too much time and resources in clinical evaluation. We employed a virtual patient model of the critically ill patient with hyperglycemia and evaluated the clinically investigat

Endocrinology, Diabetes and MetabolismMedicine
15
논문|인용수 8·2008
Comparison of a Pulsatile Blood Pump and a Peristaltic Roller Pump During Hemoperfusion Treatment in a Canine Model of Paraquat Poisoning
Jung Chan Lee, Chan Young Park, Seong Wook Choi, Jeong Chul Kim, Ki Moo Lim, Kyuseok Kim, Sung Koo Jung, Young Ho Kwak, Sang Do Shin, Ik Joon Jo, Gil Joon Suh, Byoung Goo Min
SJR Q2FWCI 0.3Artificial Organs

This study examined the treatment efficacy and the damage to the blood during hemoperfusion for treating paraquat poisoning using two blood pump mechanisms. Paraquat-poisoned animal models were prepared. A conventional hemodialysis machine, AK90, with a peristaltic roller pump and a cardiopulmonary support system, T-PLS, with a pulsatile blood pump were used during the animal experiments. A total of 12 dogs were treated with hemoperfusion using a charcoal column. Six dogs were treated with hemop

SurgeryMedicine

대표 연구 분야

Emergency MedicineBiomedical EngineeringSurgeryNephrologySpeech and HearingEndocrinology, Diabetes and Metabolism

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