한정규 교수

We demonstrated the first direct conversion of adult fibroblasts to functional ECs. These results suggest a novel therapeutic modality for cell therapy in ischemic vascular disease.

The results of our study suggest that PPAR-delta agonist has therapeutic vasculogenic potential for the treatment of ischemic cardiovascular diseases.

gov; Unique identifier: NCT02601157.

Our results suggest that PPAR-δ is a crucial modulator of angio-myogenesis via the paracrine effects of EPCs, and its agonist is a good candidate as a therapeutic drug for patients with peripheral vascular diseases.

In this pooled analysis, an IVUS MLA of 2.75 mm(2) was the BCV to define the functional significance of intermediate coronary stenosis. However, when IVUS MLA is used to determine the functional significance, both the lesion and patient characteristics should be considered.

In recommending to another individual an item that one loves, accuracy is important, however in most cases, focusing only on accuracy generates less satisfactory recommendations. Studies have repeatedly pointed out that aspects that go beyond accuracy — such as the diversity and novelty of the recommended items — are as important as accuracy in making a satisfactory recommendation. Despite their importance, there is no global consensus about definitions and evaluations regarding beyond-accuracy

Hadoop becomes de facto standard framework for big data analysis due to its scalability. Despite of the importance of Hadoop's scalability, there are a few works have been made on the scalability in multi-rack clusters. In multi-rack clusters of real world, network topology becomes a major scalability bottleneck due to the limited network switch capacity. It is a waste of resources to add servers to a Hadoop cluster in such situation. Therefore, it is helpful for users to save cost by efficientl

In recommending POIs(Point-Of-Interests), factors such as the diversity of the recommended POIs are as important as accuracy for providing a satisfactory recommendation. Although existing diversification methods can help POI recommender systems suggest more diverse POIs, they lack "geographical diversification," which results in the concentration of the supposedly "diverse" recommended POIs on "a small portion" in areas where the target-user is most active. This is caused by the neglect of POI l

In the personalized Point-Of-Interest (POI) (or venue) recommendation, the diversity of recommended POIs is an important aspect. Diversity is especially important when POIs are recommended in the target users’ frequently visited areas, because users are likely to revisit such areas. In addition to the (POI) category diversity that is a popular diversification objective in recommendation domains, diversification of recommended POI locations is an interesting subject itself. Despite its importance

From this study, there was a tendency cyst wall with the history of infection or incision and drainage is thicker. When surgical excision, more attention to excise epidermal cyst completely is needed for the prevention of recurrence of the cyst.

Since many people consume multimedia content (music, movie etc.) on mobile devices, mobile DRM becomes important, which controls digital content usage under wireless environment. In a typical DRM model, a block cipher is usually used to encrypt multimedia content because of its reasonable security and performance. However, encrypting multimedia content using a block cipher in mobile environment requires much computation power and energy due to its huge size. It is critical problems because users