김기웅 교수
Ki Woong Kim
서울대학교 · 의학
연구실 소개
김기웅 교수의 연구실은 신경퇴행성질환, 특히 알츠하이머병과 인지저하의 조기 진단 및 위험 요인 규명을 중심으로 연구를 진행하고 있습니다. 특히 한국 노인을 대상으로 한 대규모 국민 건강 조사 자료를 기반으로 인지기능 저하와 관련된 수면 패턴, 우울증, 눈 건강 등 다양한 생리적·정서적 요인의 영향을 분석하고 있으며, 인지평가 도구의 정확성 비교를 통해 보다 정밀한 진단 방법을 모색하고 있습니다. 또한 척추외과 수술의 최소침습 기법이 신경기능에 미치는 영향에 대한 기초 연구도 병행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Minimally invasive surgery for spinal disorders is predicated on the following basic principles: (1) avoid muscle crush injury by self-retaining retractors; (2) do not disrupt tendon attachment sites of key muscles, particularly the origin of the multifidus muscle at the spinous process; (3) use known anatomic neurovascular and muscle compartment planes; and (4) minimize collateral soft-tissue injury by limiting the width of the surgical corridor. The traditional midline posterior approach for l
We investigated the prevalence of dementia and mild cognitive impairment (MCI) and the factors associate with risk of dementia from a representative nationwide sample of Korean elders. 8,199 randomly-sampled Koreans aged 65 years or older were invited to participate in the Phase I screening assessment using Mini-Mental State Examination by door-to-door home visit, and 6,141 subjects (response rate = 74.9%) responded. Among them, 2,336 subjects were invited to participate in the Phase II diagnost
As early markers of cognitive decline, long sleep latency can be used for elderlies with NC or MCI, whereas long sleep duration and relatively early sleep time might be used for cognitively normal elderlies only. Ann Neurol 2018;83:472-482.
Depression was associated with DED symptoms in subjects with normal or mildly reduced tear production.
To compare the diagnostic accuracies of the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental Status Examination (MMSE) for Alzheimer's diseases (AD), we administered them simultaneously to 82 AD patients and 82 age- and sex-matched nondemented control subjects. The area under the receiver operator curve (AUC) for AD of the HDS-R (AUC(HDS-R)) and MMSE (AUC(MMSE)) were bigger than 0.90 indicating that both tests are useful for detecting AD. However, AUC(HDS-R) (0.952) was significantly larg
The number of impaired cognitive domains, but not the presence of memory impairment, predicted poor outcomes in people with MCI. However, MCI subtype was diagnostically unstable.
To prepare poly(lactic acid) (PLA) with improved mechanical properties, high-molecular-weight poly(L-lactic acid) (PLLA) was synthesized by the direct polycondensation of lactic acid in solution phase. During polymerization, the molecular weight of PLA was influenced by the water content present in the solution; thus, the experimental apparatus was designed to remove the water efficiently and this study was focused on the optimization of the polymerization conditions such as polymerization time,
In order to reduce caregiver burden in dementia effectively, psychosocial interventions should be tailored to target type of caregiver burden.
The aim of this study was to determine the prevalence, neuropsychiatric comorbidities, iron metabolism and potential risk factors of restless legs syndrome (RLS) in the elderly Korean population. As a community-based epidemiological study, a simple random sample of 1118 was drawn from a roster of 61 730 adult individuals aged 65 years and older and 714 participated. The diagnosis of RLS was established in face-to-face interviews using the four minimal diagnostic criteria for RLS recommended by N
Parity is associated with women's risk of dementia, though this is not uniform across regions and dementia subtypes.
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