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최규성 교수

Kyu Sung Choi

서울대학교 · 의학

연구실 소개

최규성 교수의 연구실은 뇌영상 영상의학과 영상유전체학 분야에서 활발히 연구를 진행하고 있습니다. 주로 동적 강화 MRI(DCE-MRI), 흐름강화 영상(DSC-MRI), 그리고 확산 영상 기반의 뇌간질환 평가 기술을 활용해 뇌종양의 유전자형(예: IDH, MGMT) 예측 및 신경퇴행성질환(다발성경화증, NMOSD)의 뇌간질환 관련 생리적 변화를 규명하고 있습니다. 특히 딥러닝 기반의 해석가능한 모델 개발을 통해 영상과 유전자 간의 관계를 정량적으로 분석하고 있으며, 정밀의료 및 조기 진단에 기여하고자 합니다.

영상유전체학뇌종양딥러닝동적강화영상뇌간질환

연구 현황

논문 수
125
총 인용 수
1,058
최근 5년 논문
82
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
82총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
408총합
20222023202420252026

주요 논문

15
1
논문|인용수 118·2019
Prediction of IDH genotype in gliomas with dynamic susceptibility contrast perfusion MR imaging using an explainable recurrent neural network
Kyu Sung Choi, Seung Hong Choi, Bumseok Jeong
SJR Q1FWCI 9.3Neuro-OncologyOA

We developed an explainable recurrent neural network model based on DSC perfusion MRI to predict IDH genotypes in gliomas.

GeneticsMedicine
2
논문|인용수 38·2022
Artificial Intelligence in Neuroimaging: Clinical Applications
Kyu Sung Choi, Leonard Sunwoo
SJR Q4FWCI 5.3Investigative Magnetic Resonance ImagingOA
Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 38·2022
Validation of MRI-Based Models to Predict MGMT Promoter Methylation in Gliomas: BraTS 2021 Radiogenomics Challenge
Byung-Hoon Kim, Hyeonhoon Lee, Kyu Sung Choi, Ju Gang Nam, Chul‐Kee Park, Sung‐Hye Park, Jin Wook Chung, Seung Hong Choi
SJR Q1FWCI 5.4CancersOA

O6-methylguanine-DNA methyl transferase (MGMT) methylation prediction models were developed using only small datasets without proper external validation and achieved good diagnostic performance, which seems to indicate a promising future for radiogenomics. However, the diagnostic performance was not reproducible for numerous research teams when using a larger dataset in the RSNA-MICCAI Brain Tumor Radiogenomic Classification 2021 challenge. To our knowledge, there has been no study regarding the

GeneticsMedicine
4
논문|인용수 27·2020
Improving the Reliability of Pharmacokinetic Parameters at Dynamic Contrast-enhanced MRI in Astrocytomas: A Deep Learning Approach
Kyu Sung Choi, Sung‐Hye You, Yoseob Han, Jong Chul Ye, Bumseok Jeong, Seung Hong Choi
SJR Q1FWCI 1.8Radiology

Background Pharmacokinetic (PK) parameters obtained from dynamic contrast agent-enhanced (DCE) MRI evaluates the microcirculation permeability of astrocytomas, but the unreliability from arterial input function (AIF) remains a challenge. Purpose To develop a deep learning model that improves the reliability of AIF for DCE MRI and to validate the reliability and diagnostic performance of PK parameters by using improved AIF in grading astrocytomas. Materials and Methods This retrospective study in

Radiology, Nuclear Medicine and ImagingMedicine
5
논문|인용수 26·2024
Comparative analysis of glymphatic system alterations in multiple sclerosis and neuromyelitis optica spectrum disorder using <scp>MRI</scp> indices from diffusion tensor imaging
Minchul Kim, Inpyeong Hwang, Jung‐Hyun Park, Jin Wook Chung, Sung Min Kim, Ji‐hoon Kim, Kyu Sung Choi
SJR Q1FWCI 7.0Human Brain MappingOA

Previous literature indicates important glymphatic system alteration in MS and NMOSD. We explore the difference between MS and NMOSD using diffusion MRI-based measures of the glymphatic system. We show support for the null hypothesis of no difference between MS and NMOSD. This suggests that glymphatic alteration associated with MS and NMOSD might be similar and common etiology.

Cellular and Molecular NeuroscienceNeuroscience
6
논문|인용수 21·2021
Deep graph neural network-based prediction of acute suicidal ideation in young adults
Kyu Sung Choi, Sunghwan Kim, Byung-Hoon Kim, Hong Jin Jeon, Jong‐Hoon Kim, Joon Hwan Jang, Bumseok Jeong
SJR Q1FWCI 1.5Scientific ReportsOA

Precise remote evaluation of both suicide risk and psychiatric disorders is critical for suicide prevention as well as for psychiatric well-being. Using questionnaires is an alternative to labor-intensive diagnostic interviews in a large general population, but previous models for predicting suicide attempts suffered from low sensitivity. We developed and validated a deep graph neural network model that increased the prediction sensitivity of suicide risk in young adults (n = 17,482 for training

Clinical PsychologyPsychology
7
논문|인용수 19·2023
Added prognostic value of 3D deep learning-derived features from preoperative MRI for adult-type diffuse gliomas
Jung Oh Lee, Sung Soo Ahn, Kyu Sung Choi, Junhyeok Lee, Joon Hwan Jang, Jung Hyun Park, Inpyeong Hwang, Chul‐Kee Park, Sung‐Hye Park, Jin Wook Chung, Seung Hong Choi
SJR Q1FWCI 5.5Neuro-OncologyOA

The global morphologic feature derived from 3D CNN models using whole-brain MRI has independent prognostic value for diffuse gliomas. Combining clinical, molecular genetic, and imaging data yields the best performance.

GeneticsMedicine
8
논문|인용수 19·2015
Evaluation of Perihilar Biliary Strictures: Does DWI Provide Additional Value to Conventional MRI?
Kyu Sung Choi, Jeong Min Lee, Ijin Joo, Joon Koo Han, Byung Ihn Choi
SJR Q1FWCI 1.2American Journal of Roentgenology

The addition of DWI to conventional MRI-MRCP did not improve diagnostic performance in the characterization of perihilar strictures or in determining whether the bilateral secondary biliary confluence was involved in perihilar cholangiocarcinomas.

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 19·2014
Feasibility and outcomes of laparoscopic enucleation for pancreatic neoplasms
Kyu Sung Choi, Jun Chul Chung, Hyung Chul Kım
SJR Q2FWCI 1.0Annals of Surgical Treatment and ResearchOA

LE is a safe and effective procedure, and should be considered as a treatment option for pancreatic lesions that do not involve the main pancratic duct and have an outgrowing aspect with small tumor bed.

OncologyMedicine
10
논문|인용수 17·2015
Percutaneous Aspiration Embolectomy Using Guiding Catheter for the Superior Mesenteric Artery Embolism
Kyu Sung Choi, Ji Dae Kim, Hyo‐Cheol Kim, Sangil Min, Seung-Kee Min, Hwan Jun Jae, Jin Wook Chung
SJR Q1FWCI 0.9Korean Journal of RadiologyOA

Percutaneous aspiration embolectomy is a useful tool in recanalization of embolic occlusion of the SMA in select patients.

SurgeryMedicine
11
논문|인용수 14·2016
Early Gastric Cancers: Is CT Surveillance Necessary after Curative Endoscopic Submucosal Resection for Cancers That Meet the Expanded Criteria?
Kyu Sung Choi, Se Hyung Kim, Sang Gyun Kim, Joon Koo Han
SJR Q1FWCI 1.0Radiology

Purpose To determine the yield of follow-up abdominopelvic computed tomography (CT) in detecting extragastric recurrence after curative endoscopic submucosal dissection (ESD) for early gastric cancers (EGCs) that meet the expanded criteria. Materials and Methods Institutional review board approval was obtained for this retrospective study, and the requirement to obtain informed consent was waived. Patients who underwent curative ESD for EGCs that met the expanded criteria between November 2005 a

Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 11·2016
Extremely Small Pseudoparamagnetic Iron Oxide Nanoparticle as a Novel Blood Pool T1 Magnetic Resonance Contrast Agent for 3 T Whole-Heart Coronary Angiography in Canines
Eun‐Ah Park, Whal Lee, Young So, Yun‐Sang Lee, Bong-sik Jeon, Kyu Sung Choi, Eung-gyu Kim, Wan-Jae Myeong
SJR Q1FWCI 0.6Investigative Radiology

The experimental blood pool agent KEG3 offers equivalent image quality for whole-heart coronary MRA at 3 T upon contrast administration and persistent better quality in the subsequent scans, compared with a traditional extracellular gadolinium-based contrast agent.

Radiology, Nuclear Medicine and ImagingMedicine
13
논문|인용수 10·2016
Intestinal malrotation in patients with situs anomaly: Implication of the relative positions of the superior mesenteric artery and vein
Kyu Sung Choi, Young Hun Choi, Jung‐Eun Cheon, Woo Sun Kim, In One Kim
SJR Q1FWCI 0.3European Journal of Radiology
SurgeryMedicine
14
논문|인용수 9·2025
Prospective Evaluation of Accelerated Brain MRI Using Deep Learning-Based Reconstruction: Simultaneous Application to 2D Spin-Echo and 3D Gradient-Echo Sequences
Kyu Sung Choi, Chanrim Park, Ji Ye Lee, Kyung Hoon Lee, Young Hun Jeon, Inpyeong Hwang, Roh‐Eul Yoo, Tae Jin Yun, Mi Ji Lee, Keun‐Hwa Jung, Koung Mi Kang
SJR Q1FWCI 10.9Korean Journal of RadiologyOA

Accel-DL substantially reduced the scan time and improved the quality of brain MRI in both spin-echo and gradient-echo sequences without compromising volumetry, including lesion quantification.

Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 8·2022
Deep Learning Applications in Perfusion MRI: Recent Advances and Current Challenges
Kyu Sung Choi
SJR Q4FWCI 1.2Investigative Magnetic Resonance ImagingOA

Deep learning has shown its feasibility for applications in medical imaging.Deep learning-based methods are also rapidly being applied in a wide range of areas to replace traditional model-based methods, showing remarkable improvements in several MR image processing areas such as image reconstruction, image contrast conversion, and image quality improvement.With improvement of perfusion MRI techniques, various clinical applications have been also researched, which have improved tracer-kinetic mo

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

Radiology, Nuclear Medicine and ImagingGeneticsNeurologyCellular and Molecular NeuroscienceArtificial IntelligencePulmonary and Respiratory Medicine

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