임이랑 교수
Leerang Lim
서울대학교 · 의학
연구실 소개
임이랑 교수의 연구실은 허혈성 뇌졸중 예방과 뇌혈관 수술의 임상적 결과를 중심으로 연구를 진행하고 있으며, 특히 경동맥 병변과 동반된 병변이 수술 결과에 미치는 영향을 분석하고 있습니다. 또한, 중환자실에서의 단기 사망률 예측을 위한 실시간 기계학습 모델 개발과, 다학제적 접근을 통한 고위험 환자 관리에 초점을 맞추고 있습니다. 최근에는 약 13만 건의 수술 기록을 포함한 공개 데이터셋 ‘INSPIRE’를 구축하여, 품질 높은 임상 연구와 모델 검증을 지원하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15It has been suggested that carotid endarterectomy for carotid bifurcation disease may be contraindicated in the presence of carotid siphon lesions. This study was undertaken to assess any difference in stroke rate, mortality, or relief of symptoms in patients with and without such "tandem" lesions following elective carotid endarterectomy. Ninety-one bifurcation endarterectomies were performed in 79 patients. The patients were divided into two groups. Group I (44 patients, 47 endarterectomies) h
Our real-time machine learning model to predict short-term mortality in critically ill patients showed excellent performance in both internal and external validations. This model could be a useful decision-support tool in the intensive care units to assist clinicians.
We present the INSPIRE dataset, a publicly available research dataset in perioperative medicine, which includes approximately 130,000 surgical operations at an academic institution in South Korea over a ten-year period between 2011 and 2020. This comprehensive dataset includes patient characteristics such as age, sex, American Society of Anesthesiologists physical status classification, diagnosis, surgical procedure code, department, and type of anaesthesia. The dataset also includes vital signs
In patients undergoing OPCAB, intraoperative rSO<sub>2</sub> reduction was associated with postoperative delirium. Duration of rSO<sub>2</sub> less than 50% was 40% longer in the patients with postoperative delirium. The cut-off value of intraoperative rSO<sub>2</sub> that associated with postoperative delirium was 50% for the total patient population and 55% for the patients younger than 68 years.
Acute kidney injury (AKI) is a frequent complication after living donor liver transplantation (LDLT), and is associated with increased mortality. However, the association between intraoperative oliguria and the risk of AKI remains uncertain for LDLT. We sought to determine the association between intraoperative oliguria alone and oliguria coupled with hemodynamic derangement and the risk of AKI after LDLT. We evaluated the hemodynamic variables, including mean arterial pressure, cardiac index, a
With the growing interest of researchers in machine learning and artificial intelligence (AI) based on large data, their roles in medical research have become increasingly prominent. Despite the proliferation of predictive models in perioperative medicine, external validation is lacking. Open datasets, defined as publicly available datasets for research, play a crucial role by providing high-quality data, facilitating collaboration, and allowing an objective evaluation of the developed models. A
This work was supported by the Korea Health Technology Research & Development Project through the Korea Health Industry Development Institute, funded by the Ministry of Health and Welfare, Republic of Korea (grant number RS-2021-KH114109).
UN에 의하면 아시아, 아프리카, 중남미의 개발도상국을 중심으로 도시화가 진전되면서 2010년에 이미 세계 인구의 절반이 도시에 살게 되었고, 앞으로도 그 속도가 더욱 빨라져 개발도상국의 도시인구는 2010년 26억 명에서 2050년 51억 명으로 크게 증가할 것으로 예상되고 있다.1) 그렇지만 도시화에 따른 불량주거지의 확산으로 전 세계 도시인구의 1/3이 슬럼(slum)과 무허가정착지(squatter)에 거주하고 있고 그 중 반 이상이 아시아에 집중되어 있는 등(UN-Habitat, 2003), 개발도상국의 주택문제는 매우 심각한 상황이다. 특히 개발도상국의 불량주거지 인구는 2010년 8.28억 명에서 2030년 22.5억 명으로 증가할 것으로 추산되는데(UN-Habitat, 2012), 이들의 주택문제를 해결하기 위해서는 가구당 5인 기준으로 2030년까지 4.5억 호의 주택이 연간 2,250만호, 하루 평균 6만호씩 공급되어야 한다. 이에 따라 개발도상국의 주택건설이 촉진되
Postoperatively, sufen-tanil in PCA provided more analgesia than fentanyl with less additional analgesics in moyamoya disease. However, PCA with sufentanil was more frequently discontinued due to nausea or vomiting compared to fentanyl-based PCA.
In critically ill patients undergoing continuous renal replacement therapy, less prolonged prothrombin time was associated with earlier catheter dysfunction. Use of left internal jugular veins and femoral vein were associated with increased risk of re-catheterization compared to the right internal jugular vein.
In the COVID-19 pandemic era, virtual visits to ICU patients helped reduce depression and anxiety levels of patients and increase the satisfaction of their family members. Enhancing access to virtual visits for family members and developing a consistent approach may improve the quality of care during another pandemic.
EPF after major upper abdominal surgery was not associated with radiologically detected atelectasis. EPF also was not associated with the increased risk of postoperative pulmonary complications, bacterial growth on culture studies, or prolonged length of hospital stay.
Using lactated Ringer's solution alone for replacement of ascites after living donor LT did not reduce the time to first flatus and was associated with an increased risk of AKI. Further research on the optimal ascites replacement regimen and the target serum albumin level which should be corrected after LT is required.
ClinicalTrials.gov Identifier NCT01489137 , retrospectively registered 5 December 2011.
Guidelines from the World Health Organization strongly recommend the use of a high fraction of inspired oxygen (FiO<sub>2</sub>) in adult patients undergoing general anesthesia to reduce surgical site infection (SSI). However, previous meta-analyses reported inconsistent results. We aimed to address this controversy by focusing specifically on abdominal surgery with relatively high risk of SSI. Medline, EMBASE, and Cochrane CENTRAL databases were searched. Randomized trials of abdominal surgery
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