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선우준 교수

Leonard Sunwoo

서울대학교 · 의학

연구실 소개

선우준 교수 연구실은 의료 영상 분석과 복원을 핵심으로 하며, 특히 자기공명영상(MRI)의 초고속 촬영 기술과 영상 재구성 알고리즘 개발에 주력하고 있습니다. 저해상도·부분 촬영된 k-공간 데이터를 효과적으로 복원하기 위한 데이터 기반 딥러닝 기반 보간 기법과, 레이저 기반 영상 해석 기술을 통해 혈관질환 및 뇌질환의 조기 진단을 가능하게 하는 연구를 진행하고 있습니다. 특히, 정규화된 데이터가 부족한 환경에서도 성능을 유지할 수 있는 비매칭 학습 기반 영상 복원 기술에 초점을 맞추고 있습니다.

의료영상초고속 MRI딥러닝 보간비매칭 학습혈관질환 진단

연구 현황

논문 수
110
총 인용 수
1,860
최근 5년 논문
60
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
60총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
308총합
20222023202420252026

주요 논문

15
1
논문|인용수 336·2019
${k}$ -Space Deep Learning for Accelerated MRI
Yoseob Han, Leonard Sunwoo, Jong Chul Ye
SJR Q1FWCI 38.7IEEE Transactions on Medical Imaging

The annihilating filter-based low-rank Hankel matrix approach (ALOHA) is one of the state-of-the-art compressed sensing approaches that directly interpolates the missing k -space data using low-rank Hankel matrix completion. The success of ALOHA is due to the concise signal representation in the k -space domain, thanks to the duality between structured low-rankness in the k -space domain and the image domain sparsity. Inspired by the recent mathematical discovery that links convolutional neural

Computational MechanicsEngineering
2
리뷰|인용수 115·2020
Brain metastasis detection using machine learning: a systematic review and meta-analysis
Se Jin Cho, Leonard Sunwoo, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Jae Hyoung Kim
SJR Q1FWCI 8.5Neuro-OncologyOA

A comparable detectability of BM with a low false-positive rate per person was found in the DL group compared with the cML group. Improvements are required in terms of quality and study design.

Pulmonary and Respiratory MedicineMedicine
3
논문|인용수 106·2018
Deep Learning in Diagnosis of Maxillary Sinusitis Using Conventional Radiography
Youngjune Kim, Kyong Joon Lee, Leonard Sunwoo, Dongjun Choi, Chang-Mo Nam, Jungheum Cho, Jihyun Kim, Yun Jung Bae, Roh‐Eul Yoo, Byung Se Choi, Cheolkyu Jung, Jae Hyoung Kim
SJR Q1FWCI 5.9Investigative Radiology

The deep learning algorithm could diagnose maxillary sinusitis on Waters' view radiograph with superior AUC and comparable sensitivity and specificity to those of radiologists.

OtorhinolaryngologyMedicine
4
논문|인용수 84·2020
Unpaired Deep Learning for Accelerated MRI Using Optimal Transport Driven CycleGAN
Gyutaek Oh, Byeongsu Sim, Hyungjin Chung, Leonard Sunwoo, Jong Chul Ye
SJR Q1FWCI 6.3IEEE Transactions on Computational Imaging

Recently, deep learning approaches for accelerated MRI have been extensively studied thanks to their high performance reconstruction in spite of significantly reduced run-time complexity. These neural networks are usually trained in a supervised manner, so matched pairs of subsampled, and fully sampled k-space data are required. Unfortunately, it is often difficult to acquire matched fully sampled k-space data, since the acquisition of fully sampled k-space data requires long scan time, and ofte

Radiology, Nuclear Medicine and ImagingMedicine
5
논문|인용수 76·2020
Effects of Hypertension, Diabetes, and Smoking on Age and Sex Prediction from Retinal Fundus Images
Yong Dae Kim, Kyoung Jin Noh, Seong Jun Byun, Soochahn Lee, Tackeun Kim, Leonard Sunwoo, Kyong Joon Lee, Si‐Hyuck Kang, Kyu Hyung Park, Sang Jun Park
SJR Q1FWCI 5.0Scientific ReportsOA

Retinal fundus images are used to detect organ damage from vascular diseases (e.g. diabetes mellitus and hypertension) and screen ocular diseases. We aimed to assess convolutional neural network (CNN) models that predict age and sex from retinal fundus images in normal participants and in participants with underlying systemic vascular-altered status. In addition, we also tried to investigate clues regarding differences between normal ageing and vascular pathologic changes using the CNN models. I

Radiology, Nuclear Medicine and ImagingMedicine
6
논문|인용수 65·2016
Differentiation of Glioblastoma from Brain Metastasis: Qualitative and Quantitative Analysis Using Arterial Spin Labeling MR Imaging
Leonard Sunwoo, Tae Jin Yun, Sung‐Hye You, Roh‐Eul Yoo, Koung Mi Kang, Seung Hong Choi, Ji‐hoon Kim, Chul‐Ho Sohn, Sun‐Won Park, Cheolkyu Jung, Chul‐Kee Park
SJR Q1FWCI 3.6PLoS ONEOA

ASL perfusion MR imaging can aid in the differentiation of GBM from brain metastasis.

GeneticsMedicine
7
논문|인용수 60·2019
Fully Automatic Segmentation of Acute Ischemic Lesions on Diffusion-Weighted Imaging Using Convolutional Neural Networks: Comparison with Conventional Algorithms
Ilsang Woo, A-Reum Lee, Seung Chai Jung, Hyunna Lee, Namkug Kim, Se Jin Cho, Donghyun Kim, Jung Bin Lee, Leonard Sunwoo, Dong‐Wha Kang
SJR Q1FWCI 4.8Korean Journal of RadiologyOA

The CNN algorithm for automatic segmentation of acute ischemic lesions on DWI achieved Dice indices greater than or equal to 0.85 and showed superior performance to conventional algorithms.

EpidemiologyMedicine
8
논문|인용수 56·2017
Computer-aided detection of brain metastasis on 3D MR imaging: Observer performance study
Leonard Sunwoo, Young Jae Kim, Seung Hong Choi, Kwang Gi Kim, Ji Hee Kang, Yeonah Kang, Yun‐Jung Bae, Roh‐Eul Yoo, Jihang Kim, Kyong Joon Lee, Seung-Hyun Lee, Byung Se Choi
SJR Q1FWCI 2.5PLoS ONEOA

CAD as a second reader helps radiologists improve their diagnostic performance in the detection of BM on MR imaging, particularly for less-experienced reviewers.

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 51·2018
Machine learning for detecting moyamoya disease in plain skull radiography using a convolutional neural network
Tackeun Kim, Jaehyuk Heo, Dong‐Kyu Jang, Leonard Sunwoo, Joonghee Kim, Kyong Joon Lee, Si‐Hyuck Kang, Sang Jun Park, O-Ki Kwon, Chang Wan Oh
SJR Q1FWCI 2.6EBioMedicineOA

DL can distinguish MMD cases within specific ages from controls in plain skull radiograph images with considerable accuracy and AUROC. The viscerocranium may play a role in MMD-related skull features. FUND: This work was supported by grant no. 18-2018-029 from the Seoul National University Bundang Hospital Research Fund.

RheumatologyMedicine
10
논문|인용수 51·2012
Correlation of apparent diffusion coefficient values measured by diffusion MRI and MGMT promoter methylation semiquantitatively analyzed with MS‐MLPA in patients with glioblastoma multiforme
Leonard Sunwoo, Seung Hong Choi, Chul‐Kee Park, Jin Wook Kim, Kyung Sik Yi, Woong Jae Lee, Tae Jin Yoon, Sang Woo Song, Ja‐Eun Kim, Ji Young Kim, Tae Min Kim, Se‐Hoon Lee
SJR Q1FWCI 1.1Journal of Magnetic Resonance ImagingOA

Abstract Purpose: To retrospectively determine whether the apparent diffusion coefficient (ADC) values correlate with O 6 ‐methylguanine DNA methyltransferase (MGMT) promoter methylation semiquantitatively analyzed by methylation‐specific multiplex ligation‐dependent probe amplification (MS‐MLPA) in patients with glioblastoma. Materials and Methods: The study was approved by the Institutional Review Board and was Health Insurance Portability and Accountability Act (HIPAA) compliant. Newly diagno

GeneticsMedicine
11
논문|인용수 50·2018
Procedural and clinical outcomes of endovascular recanalization therapy in patients with cancer-related stroke
Seunguk Jung, Cheolkyu Jung, Jae Hyoung Kim, Byung Se Choi, Yun Jung Bae, Leonard Sunwoo, Ho Geol Woo, Jun Young Chang, Beom Joon Kim, Moon‐Ku Han, Hee‐Joon Bae
SJR Q2FWCI 3.2Interventional NeuroradiologyOA

Objective Embolism due to coagulopathy might be the main pathomechanism underlying cancer-related stroke (CRS). CRS patients with a large artery occlusion could be candidates for endovascular recanalization therapy (ERT), although its procedural and clinical outcomes are not well known. This study aimed to investigate the procedural and clinical outcomes of ERT in CRS patients and the characteristics associated with outcomes compared with those of conventional stroke patients. Methods A registry

EpidemiologyMedicine
12
리뷰|인용수 48·2020
Diagnostic performance of neuromelanin-sensitive magnetic resonance imaging for patients with Parkinson’s disease and factor analysis for its heterogeneity: a systematic review and meta-analysis
Se Jin Cho, Yun Jung Bae, Jong‐Min Kim, Donghyun Kim, Sung Hyun Baik, Leonard Sunwoo, Byung Se Choi, Jae Hyoung Kim
SJR Q1FWCI 1.8European Radiology
NeurologyMedicine
13
논문|인용수 42·2021
Deep Learning for Diagnosis of Paranasal Sinusitis Using Multi-View Radiographs
Yejin Jeon, Kyeorye Lee, Leonard Sunwoo, Dongjun Choi, Dong Yul Oh, Kyong Joon Lee, Youngjune Kim, Jeong‐Whun Kim, Se Jin Cho, Sung Hyun Baik, Roh‐Eul Yoo, Yun Jung Bae
SJR Q2FWCI 6.1DiagnosticsOA

Accurate image interpretation of Waters' and Caldwell view radiographs used for sinusitis screening is challenging. Therefore, we developed a deep learning algorithm for diagnosing frontal, ethmoid, and maxillary sinusitis on both Waters' and Caldwell views. The datasets were selected for the training and validation set (<i>n</i> = 1403, sinusitis% = 34.3%) and the test set (<i>n</i> = 132, sinusitis% = 29.5%) by temporal separation. The algorithm can simultaneously detect and classify each para

OtorhinolaryngologyMedicine
14
논문|인용수 38·2022
Artificial Intelligence in Neuroimaging: Clinical Applications
Kyu Sung Choi, Leonard Sunwoo
SJR Q4FWCI 5.3Investigative Magnetic Resonance ImagingOA
Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 27·2021
Deep Learning-Based Computer-Aided Detection System for Automated Treatment Response Assessment of Brain Metastases on 3D MRI
Jungheum Cho, Young Jae Kim, Leonard Sunwoo, Gi Pyo Lee, Toan Nguyen, Se Jin Cho, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Cheolkyu Jung, Chul‐Ho Sohn, Jungho Han
SJR Q2FWCI 2.5Frontiers in OncologyOA

Our CAD showed potential for automated treatment response assessment of BM ≥ 5 mm.

Pulmonary and Respiratory MedicineMedicine

대표 연구 분야

EpidemiologyRadiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineNeurologyOtorhinolaryngologyBiomedical Engineering

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