손석호 교수
Seok Ho Sohn
서울대학교 · 의학
연구실 소개
손석호 교수의 연구실은 심장 박동수술 및 재수술 분야에서의 임상적 및 해부학적 결과를 중심으로 연구를 진행하고 있습니다. 특히, 대동맥판막교체술에서 실리콘 밸브와 레이저 드릴링 밸브의 혈역학적 차이, 재관류 수술의 장기적 경과와 관류율 향상 전략에 중점을 두고 있습니다. 또한 심방세동 환자에서의 항응고 치료 대비, 대동맥판막교체술 후 재수술의 안정성과 기능적 결과에 대한 다국적 데이터 분석도 수행하고 있습니다. 이는 환자의 장기적 생존과 삶의 질 향상을 위한 임상적 근거를 강화하는 데 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15AVR using RD valve was associated with better valve hemodynamics in terms of the MPG than AVR using SU valve, and better outcomes were observed in the RD group regarding PPI. Procedural times were longer in AVR using RD valve than SU valve. Early clinical outcomes showed no difference between RD and SU valve.
In this nationwide Korean AF population with a BPHV, DOAC was at least as effective and safe as warfarin for the prevention of systemic embolic events. These results suggest that DOAC may be an excellent alternative to warfarin in AF patients with BPHV.
Early clinical outcomes and long-term outcomes, including all-cause mortality, cardiac death, ischaemic stroke, haemorrhagic stroke and endocarditis, were comparable between bovine and porcine TVRs. However, porcine valves demonstrated a lower cumulative incidence of reoperation than bovine valves.
Redo CABG could mostly be performed using the off-pump technique and did not show increased operative mortality and morbidities.
SV grafts harvested using no-touch technique with perivascular tissue further improved the 5-year patency of SV composite grafts compared with those without perivascular tissue.
We evaluated the mid-term outcomes and angiographic patency of redo coronary artery bypass grafting (CABG). Methods: Of 2,851 patients who underwent isolated CABG at Seoul National University Hospital from 2000 to 2017, 88 underwent redo CABG. Patients' mean age at redo CABG was 66.08.0 years. The mean interval between the first-time and redo CABG was 113.062.4 months. The mean follow-up duration was 86 months. Early and mid-term clinical outcomes were evaluated. Angiographic patency rates were
Clinical outcomes of the third or more operations for valvular heart disease were acceptable in terms of intraoperative adverse events and in-hospital mortality rates. There were no differences in the incidence of intraoperative adverse events, early mortality and postoperative complications between third cardiac operation and fourth or more.
Since the first report of an in-man transcatheter aortic valve replacement (TAVR) in 2002 by Cribier et al . (1), its role in the management of severe aortic stenosis (AS) has grown rapidly.
Targeted metabolomics demonstrated various degrees of changes in the release of metabolites by the hypothermic brain. The release of most metabolites was decreased in hypothermia, whereas glutamic acid showed a distinct brain metabolism.
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