박성배 교수
Sung Bae Park
서울대학교 · 의학
연구실 소개
박성배 교수의 연구실은 척추외과 및 골다공로시스 관련 정형외과 수술의 임상적 문제를 중심으로 연구를 전개하고 있습니다. 특히 노령 환자에서의 척추 후상술에서 뼈 형성 촉진제의 임상적 적용 가능성을 탐색하며, 골다공로시스 환자의 뼈 회복 능력 향상을 위한 신규 치료 전략 개발에 주력하고 있습니다. 실험 모델로는 빈약한 뼈를 유도하는 양측 난소절제술을 활용한 골다공로시스 랩 모델 개발도 함께 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The prevalence of osteoporosis has been increasing globally. Recently surgical indications for elderly patients with osteoporosis have been increasing. However, only few strategies are available for osteoporotic patients who need spinal fusion. Osteoporosis is a result of negative bone remodeling from enhanced function of the osteoclasts. Because bone formation is the result of coupling between osteoblasts and osteoclasts, anti-resorptive agents that induce osteoclast apoptosis may not be effect
Bilateral OVX is a safe method for creating an osteopenic rat model. The significant decrease in BMD appears six weeks after bilateral OVX.
Carcinosarcoma of gallbladder (CSGB) is a rare malignancy characterized by malignant epithelial and mesenchymal components. Its pathogenesis is unknown and most CSGBs are associated with poor survival because the disease normally presents at an advanced stage, and as a result, curative resection is uncommon. This report describes a case that underwent curative resection. A 77-year-old woman presented with right upper quadrant pain. The preoperative diagnosis was gallbladder (GB) cancer, and thus
4.
Study Design. A retrospective cohort study. Objective. The objectives of the present study were to examine the changes in the number of surgeries, surgical methods selected, and reoperation rates between the years 2003 and 2008. Summary of Background Data. The selection of the appropriate surgical method between decompression-only (D) and decompression plus fusion (DF) represents a challenging clinical dilemma in patients with degenerative lumbar spinal spondylolisthesis. DF is selected in great
3.
Endovascular therapy can be successfully used as a primary treatment for the majority of patients with spinal DAVFs. Although it is difficult to perform in some patients, endovascular embolization should be the primary treatment of choice for spinal DAVF.
Whole lumbar sagittal alignment was influenced by single SA. Therefore, obtaining adequate segmental lordosis is desirable considering the effect on the whole spine for a long time.
The authors found that the laminoplasty and translaminar screw technique is feasible in the thoracic and lumbar regions, but further studies are needed to analyze the biomechanical effects and long-term outcomes in a large number of patients.
The design of the PEEK cage used may influence the SA, and this association needs to be considered when using stand-alone PEEK cages.
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