이성현 교수
Sung Hyun Lee
서울대학교 · 의학
연구실 소개
이성현 교수의 연구실은 청각 및 통증 관리 분야에서 응용된 청각 신호 처리와 마취통증의학의 임상적 응용을 중심으로 연구를 진행하고 있습니다. 특히, 소리의 전파 특성과 유량 조건에서의 오리피스 음향 임피던스를 정밀하게 분석하는 기초 연구와 함께, 외과적 수술 후 통증 완화를 위한 신경차단 및 마취 방법의 최적화에 초점을 맞추고 있습니다. 최근에는 머신러닝 기반의 만성 요추통 예측 모델 개발을 통해 조기 진단과 예방 전략 수립에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Although there are many analytical and empirical models for orifice impedance, the predicted acoustical performance when adopting any one of them sometimes shows a large discrepancy with the measured result in some cases. In order to obtain a new practical and precise empirical impedance model under grazing flow conditions, the acoustic impedance of circular orifices has been measured with a variation of the involved parameters under very carefully tested and controlled measurement conditions. T
A single preoperative injection of ESPB with ropivacaine may improve acute postoperative analgesia and emergence agitation in patients undergoing VATS.
The antioxidant activity and hepatoprotective potential of Cirsium setidens Nakai, a widely used medicinal plant, were investigated. The n-butanol (n-BuOH) fraction of leaves and roots of C. setidens had a higher 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity than the other soluble fractions. The n-BuOH fraction of roots of C. setidens had a significant hepatoprotective activity at a dose of 500 mg/kg compared to that of a standard agent. The biochemical results were confirmed
<i>Background and Objectives</i>: Chronic lower back pain (LBP) is a common clinical disorder. The early identification of patients who will develop chronic LBP would help develop preventive measures and treatment. We aimed to develop machine learning models that can accurately predict the risk of chronic LBP. <i>Materials and Methods</i>: Data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014 and 2015 (KNHANES VI-2, 3) were screened for selecting patients w
PDRN prolotherapy may improve the conservative treatment of painful rotator cuff tendinopathy for a specific subset of patients.
In this study, the survival fraction (SF) and relative biological effectiveness (RBE) of pancreatic cancer cells exposed to spread-out Bragg peak helium, carbon, oxygen, and neon ion beams are estimated from the measured microdosimetric spectra using a microdosimeter and the application of the microdosimetric kinetic (MK) model. To measure the microdosimetric spectra, a 3D mushroom silicon-on-insulator microdosimeter connected to low noise readout electronics (MicroPlus probe) was used. The para
The CdTe-ZnTe or CdTe–MnTe alloy system is evaluated for application in high efficiency polycrystalline thin film multijunction solar cells. CdZnTe alloy films with 1.6 and 1.7 eV band gap and CdMnTe with 1.6 and 1.8 eV were deposited by RF magnetron sputtering from targets made of mixed powders of CdTe and ZnTe (25% and 40%) or MnTe (13% and 25%), respectively. Without postdeposition treatment, however, both of these alloy films exhibit quite low photovoltaic performance when used to make cells
We developed and validated machine learning models for predicting PONV in the first 24 h. The machine learning model showed better performance than the Apfel model in predicting PONV.
The effects of gamma irradiation on the survival and development of C. sinensis metacercariae were studied to evaluate the feasibility of irradiation as a control measure for clonorchiasis. Pseudorasbora parva were collected at an endemic river of clonorchiasis and were used for irradiation of the fluke in three schemes. The first (Scheme 1) was irradiation of the isolated metacercariae from the fish followed by infection to experimental rats. The second (Scheme 2) was irradiation of the fish, a
SC administration of PDRN results in the attenuation of allodynia and activation of astrocytes in neuropathic pain or CRPS models. We propose that PDRN can have significant potential advantages in neuropathic pain treatment.
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