김수정 교수

Authentic intangible cultural heritage (ICH) provides a community with a unique selling point in the globally competitive tourism industry. The process of commodification of ICH, however, has threatened its authenticity and thus sustainable tourism approaches are required to achieve successful transmission and promotion of ICH as a sustainable tourism resource. This paper explores the priorities of ICH practitioners in relation to the development of ICH as a sustainable tourism resource, by util

In cells, biosynthetic machinery coordinates protein synthesis and folding to optimize efficiency and minimize off-pathway outcomes. However, it has been difficult to delineate experimentally the mechanisms responsible. Using fluorescence resonance energy transfer, we studied cotranslational folding of the first nucleotide-binding domain from the cystic fibrosis transmembrane conductance regulator. During synthesis, folding occurred discretely via sequential compaction of N-terminal, α-helical,

This study employs the theory of reasoned action and protection motivation theory to predict American and Korean students’ intentions to engage in behaviors that can help mitigate climate change. The results indicate that one’s attitudes toward the prevention of climate change, perceived severity of climate change, response efficacy, and self-efficacy regarding climate change prevention were significant predictors of one’s intentions to engage in a series of pro-environmental behaviors. In addit

Despite the increasing popularity and advantage of native advertising on social media, advertisers are concerned about the possibility of native ads misleading consumers, resulting in boomerang effects. This study attempts to address this concern by comparing the predictive role of native ad nonintrusiveness with that of native ad manipulativeness in consumers’ attitude toward and sharing intention of native advertising. Findings from an online survey of 550 U.S. adult consumers showed that nati

Dapagliflozin treatment showed beneficial effects on diabetic nephropathy, which might be via suppression of renal RAS component expression, oxidative stress and interstitial fibrosis in OLETF rats. We suggest that, in addition to control of hyperglycemia, partial suppression of renal RAS with an SGLT2 inhibitor would be a promising strategy for the prevention of treatment of diabetic nephropathy.

Abstract This study examines the criteria questioners use to select the best answers in a social Q&A site (Yahoo! Answers) within the theoretical framework of relevance research. A social Q&A site is a novel environment where people voluntarily ask and answer questions. In Yahoo! Answers, the questioner selects the answer that best satisfies his or her question and leaves comments on it. Under the assumption that the comments reflect the reasons why questioners select particular answers

The purpose of this study was to identify the key success factors of medical tourism using the case of South Korea. Medical tourism refers to the phenomenon of travelling across national borders intentionally to access a variety of medical treatments, especially modern medical treatment. Through conducting semi-structure face-to-face in-depth interviews with the service suppliers of Korean medical tourism, it was discovered that Korean medical tourism has been facilitated by the effect of Hallyu

In improving energy efficiency of buildings, windows play a significant role as they largely influence the energy load. Although there are many studies about the energy efficient window design, a rigorous study is missing which analyzes the mutual impact of windows’ size, position and orientation on the energy load. This study aims to address this gap through a case study on a single family house. For this aim, 65 different design scenarios are created which vary by window size, position and ori

Abstract As an attempt to better understand how people seek, share, and evaluate information in a social Q&A environment, this study identifies the selection criteria people employ when they select best answers in Yahoo! Answers in the context of relevance research. Using content analysis, we analyzed the comments people left upon the selection of best answers to their own questions. From 1,200 samples of comments, only 465 mentioned the specific reasons for their selection, thus becoming el

In the past decade much has been learned about how Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) folds and misfolds as the etiologic cause of cystic fibrosis (CF). CFTR folding is complex and hierarchical, takes place in multiple cellular compartments and physical environments, and involves several large networks of folding machineries. Insertion of transmembrane (TM) segments into the endoplasmic reticulum (ER) membrane and tertiary folding of cytosolic domains begin cotranslationa

The prion protein (PrP) is synthesized in three topologic forms at the endoplasmic reticulum. (sec)PrP is fully translocated into the endoplasmic reticulum lumen, whereas (Ntm)PrP and (Ctm)PrP are single-spanning membrane proteins of opposite orientation. Increased generation of (Ctm)PrP in either transgenic mice or humans is associated with the development of neurodegenerative disease. To study the mechanisms by which PrP can achieve three topologic outcomes, we analyzed the translocation of pr

본 연구의 목적은 과부담의료비 지출 가구와 미충족 의료 경험 가구의 현황을 사회경제적 상태의 차이를 중심으로 파악하는 것이며 2006년 차상위계층조사자료를 분석하였다. 연구 결과, 과부담의료비 지출 가구 비율은 전체 가구의 약 2% 수준이었고 소득수준이 낮은 가구일수록 이 비중은 높아졌으며 특히 건강보험빈곤, 건강보험차상위 가구의 과부담의료비 비율이 높았다. 과부담의료비 지출 가구를 결정하는 주요 요인은 가구주의 경제 활동 상태, 교육수준, 가구원 수 및 장애/만성질환자/노인 가구원 유무 등이었다. 한편 조사대상 가구의 약 12%가 미충족 의료 경험이 있음을 보고하였는데, 과부담의료비 지출 가구와는 달리 의료급여빈곤 및 의료급여차상위 가구에서 필요한 보건의료서비스 이용을 포기하거나 지연한 경험이 더 많은 것으로 나타났다. 미충족 의료 경험과 관련된 요인은 가구주 성별, 연령 및 가구 내 만성질환자 유무 등이었다. 본 연구 결과를 바탕으로 건강보험의 보장성정책과 관련하여 저소득층에서

The decisive events that direct a single polypeptide such as the prion protein (PrP) to be synthesized at the endoplasmic reticulum in both fully translocated and transmembrane forms are poorly understood. In this study, we demonstrate that the topological heterogeneity of PrP is determined cotranslationally, while at the translocation channel. By evaluating sequential intermediates during PrP topogenesis, we find that signal sequence-mediated initiation of translocation results in an interactio