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양태진 교수

Taehun Yang

서울대학교 · 생화학·유전·분자생물학

연구실 소개

양태진 교수의 연구실은 식물 유전체학과 진화 생물학을 중심으로, 특히 고산식물인 인삼과 관련된 복합 유전체 구조와 진화를 밝히는 데 초점을 맞추고 있습니다. 대표적으로 편도균류(Epimedium)와 인삼속(Panax) 식물의 엽록체 게놈 및 핵 린프리어 DNA를 고차원적으로 분석하여 유전자 구조의 보존성과 변동성을 규명하고 있으며, 전장 게놈 복제와 다형성의 진화적 의미를 탐구하고 있습니다. 특히 인삼의 장기적 생장과 복잡한 유전체 구조를 해소하기 위한 고해상도 유전체 분석과 바코드 기반 식별 기술 개발도 핵심 과제입니다.

인삼 유전체엽록체 게놈전장 게놈 복제유전자 진화바코드 분석

연구 현황

논문 수
366
총 인용 수
11,354
최근 5년 논문
72
주요 분야
생화학·유전·분자생물학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
72총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
277총합
20222023202420252026

주요 논문

15
1
논문|인용수 243·2006
Sequence-Level Analysis of the Diploidization Process in the Triplicated<i>FLOWERING LOCUS C</i>Region of<i>Brassica rapa</i>
Tae‐Jin Yang, Jung Sun Kim, Soo-Jin Kwon, Ki‐Byung Lim, Beom‐Soon Choi, Jin‐A Kim, Mina Jin, Jee Young Park, Myung-Ho Lim, Ho-Il Kim, Yong Pyo Lim, Jason Kang
SJR Q1FWCI 23.6The Plant CellOA

Strong evidence exists for polyploidy having occurred during the evolution of the tribe Brassiceae. We show evidence for the dynamic and ongoing diploidization process by comparative analysis of the sequences of four paralogous Brassica rapa BAC clones and the homologous 124-kb segment of Arabidopsis thaliana chromosome 5. We estimated the times since divergence of the paralogous and homologous lineages. The three paralogous subgenomes of B. rapa triplicated 13 to 17 million years ago (MYA), ver

Plant ScienceAgricultural and Biological Sciences
2
논문|인용수 224·2016
The Complete Chloroplast Genome Sequences of Five Epimedium Species: Lights into Phylogenetic and Taxonomic Analyses
Yanjun Zhang, Liuwen Du, Ao Liu, Jianjun Chen, Li-Wei Wu, Weiming Hu, Wei Zhang, Kyung‐Hee Kim, Dong‐Kyu Lee, Tae‐Jin Yang, Ying Wang
SJR Q1FWCI 31.1Frontiers in Plant ScienceOA

Epimedium L. is a phylogenetically and economically important genus in the family Berberidaceae. We here sequenced the complete chloroplast (cp) genomes of four Epimedium species using Illumina sequencing technology via a combination of de novo and reference-guided assembly, which was also the first comprehensive cp genome analysis on Epimedium combining the cp genome sequence of E. koreanum previously reported. The five Epimedium cp genomes exhibited typical quadripartite and circular structure

PharmacologyPharmacology, Toxicology and Pharmaceutics
3
논문|인용수 219·2018
Genome and evolution of the shade‐requiring medicinal herb <i>Panax ginseng</i>
Nam‐Hoon Kim, Murukarthick Jayakodi, Sang‐Choon Lee, Beom‐Soon Choi, Woojong Jang, Junki Lee, Hyun Hee Kim, Nomar Espinosa Waminal, Meiyappan Lakshmanan, Binh van Nguyen, Yun Sun Lee, Hyun‐Seung Park
SJR Q1FWCI 9.5Plant Biotechnology JournalOA

Panax ginseng C. A. Meyer, reputed as the king of medicinal herbs, has slow growth, long generation time, low seed production and complicated genome structure that hamper its study. Here, we unveil the genomic architecture of tetraploid P. ginseng by de novo genome assembly, representing 2.98 Gbp with 59 352 annotated genes. Resequencing data indicated that diploid Panax species diverged in association with global warming in Southern Asia, and two North American species evolved via two intercont

Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
논문|인용수 188·2015
Comprehensive Survey of Genetic Diversity in Chloroplast Genomes and 45S nrDNAs within Panax ginseng Species
Kyung‐Hee Kim, Sang‐Choon Lee, Junki Lee, Hyun Oh Lee, Ho Jun Joh, Nam‐Hoon Kim, Hyun-Seung Park, Tae‐Jin Yang
SJR Q1FWCI 11.8PLoS ONEOA

We report complete sequences of chloroplast (cp) genome and 45S nuclear ribosomal DNA (45S nrDNA) for 11 Panax ginseng cultivars. We have obtained complete sequences of cp and 45S nrDNA, the representative barcoding target sequences for cytoplasm and nuclear genome, respectively, based on low coverage NGS sequence of each cultivar. The cp genomes sizes ranged from 156,241 to 156,425 bp and the major size variation was derived from differences in copy number of tandem repeats in the ycf1 gene and

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
논문|인용수 158·2018
Comprehensive comparative analysis of chloroplast genomes from seven Panax species and development of an authentication system based on species-unique single nucleotide polymorphism markers
Van Binh Nguyen, Giang N. L. Vo, Nomar Espinosa Waminal, Hyun-Seung Park, Nam‐Hoon Kim, Woojong Jang, Junki Lee, Tae‐Jin Yang
SJR Q1FWCI 4.5Journal of Ginseng ResearchOA

The comparative analysis of chloroplast genomes from seven <i>Panax</i> species elucidated their genetic diversity and evolutionary relationships, and 18 species-specific markers were able to discriminate among these species, thereby furthering efforts to protect the ginseng industry from economically motivated adulteration.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 119·2018
Ginseng Genome Database: an open-access platform for genomics of Panax ginseng
Murukarthick Jayakodi, Beom‐Soon Choi, Sang‐Choon Lee, Nam‐Hoon Kim, Jee Young Park, Woojong Jang, Meiyappan Lakshmanan, Shobhana V. Gnanapanditha Mohan, Dong‐Yup Lee, Tae‐Jin Yang
SJR Q1FWCI 6.8BMC Plant BiologyOA

This database provides valuable resources for a range of research fields related to P. ginseng and other species belonging to the Apiales order as well as for plant research communities in general. Ginseng genome database can be accessed at http://ginsengdb.snu.ac.kr /.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 90·2011
Development of Reproducible EST-derived SSR Markers and Assessment of Genetic Diversity in Panax ginseng Cultivars and Related Species
Hong‐Il Choi, Nam‐Hoon Kim, Jun-Ha Kim, Beom-Soon Choi, In-Ok Ahn, Joon Soo Lee, Tae‐Jin Yang
SJR Q1FWCI 1.5Journal of Ginseng ResearchOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 90·2015
Genotyping-by-sequencing map permits identification of clubroot resistance QTLs and revision of the reference genome assembly in cabbage (<i>Brassica oleracea</i>L.)
Jonghoon Lee, Nur Izzah, Beom-Soon Choi, Ho Jun Joh, Dong‐Kyu Lee, Sampath Perumal, Joodeok Seo, Kyounggu Ahn, Eun Ju Jo, Gyung Ja Choi, Ill‐Sup Nou, Yeisoo Yu
SJR Q1FWCI 14.0DNA ResearchOA

Clubroot is a devastating disease caused by Plasmodiophora brassicae and results in severe losses of yield and quality in Brassica crops. Many clubroot resistance genes and markers are available in Brassica rapa but less is known in Brassica oleracea. Here, we applied the genotyping-by-sequencing (GBS) technique to construct a high-resolution genetic map and identify clubroot resistance (CR) genes. A total of 43,821 SNPs were identified using GBS data for two parental lines, one resistant and on

Plant ScienceAgricultural and Biological Sciences
9
논문|인용수 89·2015
Comprehensive analysis of Panax ginseng root transcriptomes
Murukarthick Jayakodi, Sang‐Choon Lee, Yun Sun Lee, Hyun-Seung Park, Nam‐Hoon Kim, Woojong Jang, Hyun Oh Lee, Ho Jun Joh, Tae‐Jin Yang
SJR Q1FWCI 3.5BMC Plant BiologyOA

Our analysis provides new insights into the role of the root transcriptome in development and secondary metabolite biosynthesis in P. ginseng.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
논문|인용수 78·2017
Evolution of the Araliaceae family inferred from complete chloroplast genomes and 45S nrDNAs of 10 Panax-related species
Kyung‐Hee Kim, Van Binh Nguyen, Jingzhou Dong, Ying Wang, Jee Young Park, Sang‐Choon Lee, Tae‐Jin Yang
SJR Q1FWCI 2.4Scientific ReportsOA

We produced complete sequences and conducted comparative analysis of the maternally inherited chloroplast (cp) genomes and bi-parentally inherited 45S nuclear ribosomal RNA genes (nrDNA) from ten Araliaceae species to elucidate the genetic diversity and evolution in that family. The cp genomes ranged from 155,993 bp to 156,730 bp with 97.1-99.6% similarity. Complete 45S nrDNA units were about 11 kb including a 5.8-kb 45S cistron. Among 79 cp protein-coding genes, 74 showed nucleotide variations

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
논문|인용수 76·2005
The Korea <i>Brassica</i> Genome Project: A glimpse of the <i>Brassica</i> genome based on comparative genome analysis with <i>Arabidopsis</i>
Tae‐Jin Yang, Jung‐Sun Kim, Ki‐Byung Lim, Soo‐Jin Kwon, Jin‐A Kim, Mina Jin, Jee Young Park, Myung‐Ho Lim, Ho‐Il Kim, Seog Hyung Kim, Yong Pyo Lim, Beom‐Seok Park
FWCI 8.7Comparative and Functional GenomicsOA

A complete genome sequence provides unlimited information in the sequenced organism as well as in related taxa. According to the guidance of the Multinational Brassica Genome Project (MBGP), the Korea Brassica Genome Project (KBGP) is sequencing chromosome 1 (cytogenetically oriented chromosome #1) of Brassica rapa. We have selected 48 seed BACs on chromosome 1 using EST genetic markers and FISH analyses. Among them, 30 BAC clones have been sequenced and 18 are on the way. Comparative genome ana

Plant ScienceAgricultural and Biological Sciences
12
논문|인용수 68·2013
Enhancement of Anti-Inflammatory Activity of Aloe vera Adventitious Root Extracts through the Alteration of Primary and Secondary Metabolites via Salicylic Acid Elicitation
Yun Sun Lee, Hyun Kyoung Ju, Yeon Jeong Kim, Tae‐Gyu Lim, Md. Romij Uddin, Yeon Bok Kim, Jin Hong Baek, Sung Won Kwon, Ki Won Lee, Hak Soo Seo, Sang Un Park, Tae‐Jin Yang
SJR Q1FWCI 4.2PLoS ONEOA

Aloe vera (Asphodeloideae) is a medicinal plant in which useful secondary metabolites are plentiful. Among the representative secondary metabolites of Aloe vera are the anthraquinones including aloe emodin and chrysophanol, which are tricyclic aromatic quinones synthesized via a plant-specific type III polyketide biosynthesis pathway. However, it is not yet clear which cellular responses can induce the pathway, leading to production of tricyclic aromatic quinones. In this study, we examined the

Plant ScienceAgricultural and Biological Sciences
13
논문|인용수 65·2014
Major repeat components covering one‐third of the ginseng (<i><scp>P</scp>anax ginseng</i> C.A. Meyer) genome and evidence for allotetraploidy
Hong‐Il Choi, Nomar Espinosa Waminal, Hye Mi Park, Nam‐Hoon Kim, Beom Soon Choi, Minkyu Park, Doil Choi, Yong Pyo Lim, Soo‐Jin Kwon, Beom‐Seok Park, Hyun Hee Kim, Tae‐Jin Yang
SJR Q1FWCI 10.3The Plant Journal

Ginseng (Panax ginseng) is a famous medicinal herb, but the composition and structure of its genome are largely unknown. Here we characterized the major repeat components and inspected their distribution in the ginseng genome. By analyzing three repeat-rich bacterial artificial chromosome (BAC) sequences from ginseng, we identified complex insertion patterns of 34 long terminal repeat retrotransposons (LTR-RTs) and 11 LTR-RT derivatives accounting for more than 80% of the BAC sequences. The LTR-

Plant ScienceAgricultural and Biological Sciences
14
논문|인용수 64·2014
Practical application of DNA markers for high-throughput authentication of Panax ginseng and Panax quinquefolius from commercial ginseng products
Juyeon Jung, Kyung‐Hee Kim, Kiwoung Yang, Kyong-Hwan Bang, Tae‐Jin Yang
SJR Q1FWCI 3.3Journal of Ginseng ResearchOA

Korean ginseng (Panax ginseng) and American ginseng (Panax quinquefolius) are widely used medicinal plants with similar morphology but different medicinal efficacy. Roots, flowers, and processed products of Korean and American ginseng can be difficult to differentiate from each other, leading to illegal trade in which one species is sold as the other. This study was carried out to develop convenient and reliable chloroplast genome-derived DNA markers for authentication of Korean and American gin

Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
논문|인용수 61·2014
Transcriptome profiling and comparative analysis of Panax ginseng adventitious roots
Murukarthick Jayakodi, Sang‐Choon Lee, Hyun-Seung Park, Woojong Jang, Yun Sun Lee, Beom‐Soon Choi, Gyoung Ju Nah, Do‐Soon Kim, N. Senthil, Chao Sun, Tae‐Jin Yang
SJR Q1FWCI 3.0Journal of Ginseng ResearchOA

This study will provide a comprehensive insight into the transcriptome of ginseng adventitious roots, and a way for successful transcriptome analysis and profiling of resource plants with less genomic information. The transcriptome profiling data generated in this study are available in our newly created adventitious root transcriptome database (http://im-crop.snu.ac.kr/transdb/index.php) for public use.

Molecular BiologyBiochemistry, Genetics and Molecular Biology

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Molecular BiologyPlant ScienceGeneticsPharmacologyEcology, Evolution, Behavior and SystematicsComplementary and alternative medicine

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