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김완희 교수

WanHee Kim

서울대학교 Major Lab of Veterinary Surgery · 의학

연구실 소개

김완희 교수의 연구실은 생체재료와 유전자 조절 기반의 조직 공학을 핵심으로 하여, 특히 피부 및 뼈 조직의 재생을 위한 혁신적 치료 전략을 개발하고 있습니다. 어린이 및 노령 동물 모델을 활용한 실험을 통해 아드레날린 유래 줄기세포(ASCs)와 무세포 피부기저막(ADM)을 조합한 치료법의 유효성을 입증하고 있으며, 저강도 레이저 치료(Low-Level Laser Therapy, LLLT)와의 병용 효과도 규명하고 있습니다. 또한 식물의 면역 반응 기전과 동물의 대사질환 관련 분자 메커니즘에 대한 기초 연구를 병행하여, 다양한 생물학적 문제에 대한 통합적 접근을 선도하고 있습니다.

조직공학줄기세포뼈재생무세포기저막면역반응

연구 현황

논문 수
306
총 인용 수
2,940
최근 5년 논문
27
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
27총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
132총합
20212022202320242025

주요 논문

15
1
book|인용수 72·1962
Topological Analysis and Synthesis of Communication Networks
Wan Hee Kim, R. T. Chien
FWCI 6.1Columbia University Press eBooks

Presents a uniform approach to various engineering problems, such as analysis and synthesis of electrical networks, sampled-data feedback, control systems, switching networks, and communications nets

Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
논문|인용수 72·2012
Enhanced wound healing effect of canine adipose-derived mesenchymal stem cells with low-level laser therapy in athymic mice
Hyoju Kim, Kyuseok Choi, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q1FWCI 4.7Journal of Dermatological Science
Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 64·2013
Low‐level laser therapy promotes the osteogenic potential of adipose‐derived mesenchymal stem cells seeded on an acellular dermal matrix
Kyuseok Choi, Byung‐Jae Kang, Hyoju Kim, Seungmin Lee, Sohee Bae, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q2FWCI 5.6Journal of Biomedical Materials Research Part B Applied BiomaterialsOA

This study investigates the feasibility of using an adipose-derived mesenchymal stem cell (ASC)-seeded acellular dermal matrix (ADM) along with low-level laser therapy (LLLT) to repair bone defect in athymic nude mice. Critical-sized calvarial defects were treated either with ADM, ADM/LLLT, ADM/ASCs, or ADM/ASCs/LLLT. In micro-computed tomography scans, the ADM/ASCs and the ADM/ASCs/LLLT groups showed remarkable bone formation after 14 days. Additionally, bone regeneration in the ADM/ASCs/LLLT g

Radiology, Nuclear Medicine and ImagingMedicine
4
논문|인용수 43·2017
Associations between serum leptin levels, hyperlipidemia, and cholelithiasis in dogs
Sungin Lee, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q1FWCI 2.9PLoS ONEOA

Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele. Previous studies revealed a positive association between hyperlipidemia and gallstones in humans. However, the latter is still unclear in dogs with cholelithiasis. In this study, we examined the differences in leptin, leptin receptor, total cholesterol, and triglyceride levels between health

Endocrine and Autonomic SystemsNeuroscience
5
논문|인용수 21·2018
Feasibility of single‐port retroperitoneoscopic adrenalectomy in dogs
Jonghyeok Ko, Junemoe Jeong, Sungin Lee, Hyunglak Son, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q1FWCI 3.4Veterinary SurgeryOA

This study suggests that SPRA is feasible and can be used to resect small adrenal tumors with minimal complications.

Small AnimalsVeterinary
6
논문|인용수 20·2012
Effect of acellular dermal matrix as a delivery carrier of adipose‐derived mesenchymal stem cells on bone regeneration
Hee Jung Kim, Sung Su Park, Sun Young Oh, Hyoju Kim, Oh‐Kyeong Kweon, Heung‐Myong Woo, Wan Hee Kim
SJR Q2FWCI 0.9Journal of Biomedical Materials Research Part B Applied Biomaterials

The purpose of this study is to evaluate the effect of acellular dermal matrix (ADM) as a delivery carrier of adipose-derived mesenchymal stem cells (ASCs) on bone regeneration in athymic murine calvarial bone defect. Paired-critical size defects in nude rat skull were made. The right-side defects received ASCs/ADM or only ADM, whereas the left-side defect was not treated. In 3D images, new bone formation in the ASCs/ADM group was apparent at 4 wk, but in the ADM group at 8 wk. At 4 and 8 wk, bo

GeneticsMedicine
7
논문|인용수 12·2016
Retroperitoneal Laparoscopy in Dogs: Access Technique, Working Space, and Surgical Anatomy
Junemoe Jeong, Jonghyeok Ko, Hyunjoo Lim, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q1FWCI 0.9Veterinary SurgeryOA

The retroperitoneal access technique and working space establishment with CO<sub>2</sub> insufflation starting with 5 mmHg and increasing to 10 mmHg provided adequate working space and visualization of retroperitoneal organs, which may allow direct access for retroperitoneal laparoscopy in dogs.

SurgeryMedicine
8
논문|인용수 12·2020
Perception of unrelated microbe-associated molecular patterns triggers conserved yet variable physiological and transcriptional changes in Brassica rapa ssp. pekinensis
Wanhui Kim, Maxim Prokchorchik, Yonghua Tian, Seulgi Kim, Hyelim Jeon, Cécile Segonzac
SJR Q1FWCI 1.4Horticulture ResearchOA

Pattern-triggered immunity (PTI) includes the different transcriptional and physiological responses that enable plants to ward off microbial invasion. Surface-localized pattern-recognition receptors (PRRs) recognize conserved microbe-associated molecular patterns (MAMPs) and initiate a branched signaling cascade that culminate in an effective restriction of pathogen growth. In the model species Arabidopsis thaliana, early PTI events triggered by different PRRs are broadly conserved although thei

Plant ScienceAgricultural and Biological Sciences
9
논문|인용수 11·2020
Ectopic Cushing’s syndrome associated with a pheochromocytoma in a dog: a case report
Sungin Lee, Aeri Lee, Suh-Hyun Chai, Seulji Lee, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q1FWCI 1.3BMC Veterinary ResearchOA

Pheochromocytoma should be considered a differential diagnosis for dogs with Cushing's syndrome with an adrenal tumor. A good prognosis can be expected with prompt diagnosis and surgical intervention.

Endocrinology, Diabetes and MetabolismMedicine
10
논문|인용수 9·2025
State of health prediction of lithium-ion batteries with adaptive loss-based graph neural network
Wan Hee Kim, Yongmann M. Chung, Björn Stinner
SJR Q1FWCI 6.1Journal of Energy StorageOA

Accurate state-of-health (SoH) prediction of lithium-ion batteries (LiBs) is a critical step in LiBs health prognostics to ensure its reliable operation and safety. Recently, there has been an increase in graph neural network (GNN) adaptation across many fields including LiBs health prognostics, which have shown benefits of spatio-temporal-based neural networks over the traditional counterparts. However, many of these studies have been shown to rely on discharge profiles as part of their input f

Automotive EngineeringEngineering
11
논문|인용수 9·2023
The Ralstonia pseudosolanacearum Type III Effector RipL Delays Flowering and Promotes Susceptibility to Pseudomonas syringae in Arabidopsis thaliana
Wanhui Kim, Hyelim Jeon, Hyeonjung Lee, Kee Hoon Sohn, Cécile Segonzac
SJR Q1FWCI 3.6Molecules and CellsOA

The plant defense responses to microbial infection are tightly regulated and integrated with the developmental program for optimal resources allocation. Notably, the defense- associated hormone salicylic acid (SA) acts as a promoter of flowering while several plant pathogens actively target the flowering signaling pathway to promote their virulence or dissemination. <i>Ralstonia pseudosolanacearum</i> inject tens of effectors in the host cells that collectively promote bacterial proliferation in

Plant ScienceAgricultural and Biological Sciences
12
논문|인용수 9·2012
Effects of shadow fading in indoor RSSI ranging
Wan Hee Kim, Manho Park, Sook-Jin Lee
FWCI 0.7

Received signal strength indication method enables flexible positioning without additional hardware installation and modification from communication resources. The expectation value of distance is changed due to the shadow fading. The effects of shadow fading in indoor RSSI ranging and convergence with pedestrian dead reckoning by using Extended Kalman Filter are presented. The fusion of pedestrian dead reckoning and RSSI ranging simulation shows that the compensation Shadow Fading effect has sl

Electrical and Electronic EngineeringEngineering
13
논문|인용수 7·2022
Down-expression of klotho in canine mammary gland tumors and its prognostic significance
Heaji Chung, Sungin Lee, Geon A Kim, Wan Hee Kim
SJR Q1FWCI 1.1PLoS ONEOA

Since the discovery of klotho as an anti-aging gene, its association with tumors has been studied. Several previous studies have reported the down-expression of klotho in various human cancers, and much of its mechanism has been revealed. Nonetheless, the significance of klotho in canine mammary gland tumors is not yet known. This study aimed to determine whether klotho is expressed within normal canine mammary glands and whether the expression changes in benign and malignant tumors. Using immun

GeneticsBiochemistry, Genetics and Molecular Biology
14
논문|인용수 7·1961
Application of graph theory to the analysis of active and mutually coupled networks
Wan Hee Kim
SJR Q1FWCI 1.1Journal of the Franklin Institute
Atomic and Molecular Physics, and OpticsPhysics and Astronomy
15
논문|인용수 7·2016
Presence and distribution of leptin and leptin receptor in the canine gallbladder
Sungin Lee, Aeri Lee, Oh‐Kyeong Kweon, Wan Hee Kim
SJR Q2FWCI 0.8Acta HistochemicaOA

The hormone leptin is produced by mature adipocytes and plays an important role in regulating food intake and energy metabolism through its interaction with the leptin receptor. In addition to roles in obesity and obesity-related diseases, leptin has been reported to affect the components and secretion of bile in leptin-deficient mice. Furthermore, gallbladder diseases such as cholelithiasis are known to be associated with serum leptin concentrations in humans. We hypothesized that the canine ga

Endocrine and Autonomic SystemsNeuroscience

대표 연구 분야

Small AnimalsGeneticsPulmonary and Respiratory MedicineSurgeryAerospace EngineeringPathology and Forensic Medicine

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